Atomistry » Zinc » PDB 2aqq-2b63 » 2ayk
Atomistry »
  Zinc »
    PDB 2aqq-2b63 »
      2ayk »

Zinc in PDB 2ayk: Inhibitor-Free Catalytic Fragment of Human Fibroblast Collagenase, uc(Nmr), Minimized Average Structure

Enzymatic activity of Inhibitor-Free Catalytic Fragment of Human Fibroblast Collagenase, uc(Nmr), Minimized Average Structure

All present enzymatic activity of Inhibitor-Free Catalytic Fragment of Human Fibroblast Collagenase, uc(Nmr), Minimized Average Structure:
3.4.24.7;

Other elements in 2ayk:

The structure of Inhibitor-Free Catalytic Fragment of Human Fibroblast Collagenase, uc(Nmr), Minimized Average Structure also contains other interesting chemical elements:

Calcium (Ca) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Inhibitor-Free Catalytic Fragment of Human Fibroblast Collagenase, uc(Nmr), Minimized Average Structure (pdb code 2ayk). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Inhibitor-Free Catalytic Fragment of Human Fibroblast Collagenase, uc(Nmr), Minimized Average Structure, PDB code: 2ayk:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 2ayk

Go back to Zinc Binding Sites List in 2ayk
Zinc binding site 1 out of 2 in the Inhibitor-Free Catalytic Fragment of Human Fibroblast Collagenase, uc(Nmr), Minimized Average Structure


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Inhibitor-Free Catalytic Fragment of Human Fibroblast Collagenase, uc(Nmr), Minimized Average Structure within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn170

b:0.4
occ:1.00
NE2 A:HIS122 2.0 0.4 1.0
NE2 A:HIS118 2.1 0.3 1.0
NE2 A:HIS128 2.1 0.5 1.0
CE1 A:HIS118 2.9 0.4 1.0
CE1 A:HIS122 2.9 0.5 1.0
CD2 A:HIS122 3.1 0.3 1.0
HE1 A:HIS118 3.1 0.5 1.0
CE1 A:HIS128 3.1 0.9 1.0
CD2 A:HIS128 3.2 0.6 1.0
HE1 A:HIS122 3.2 0.7 1.0
CD2 A:HIS118 3.2 0.3 1.0
HE1 A:HIS128 3.3 1.4 1.0
HD2 A:HIS122 3.3 0.4 1.0
HD2 A:HIS128 3.4 1.1 1.0
HD2 A:HIS118 3.5 0.5 1.0
ND1 A:HIS122 4.1 0.5 1.0
ND1 A:HIS118 4.1 0.4 1.0
CG A:HIS122 4.2 0.3 1.0
CG A:HIS118 4.2 0.3 1.0
ND1 A:HIS128 4.3 1.1 1.0
CG A:HIS128 4.3 0.5 1.0
HE2 A:MET136 4.4 1.2 1.0
HD1 A:HIS122 5.0 0.7 1.0
HD1 A:HIS118 5.0 0.6 1.0

Zinc binding site 2 out of 2 in 2ayk

Go back to Zinc Binding Sites List in 2ayk
Zinc binding site 2 out of 2 in the Inhibitor-Free Catalytic Fragment of Human Fibroblast Collagenase, uc(Nmr), Minimized Average Structure


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Inhibitor-Free Catalytic Fragment of Human Fibroblast Collagenase, uc(Nmr), Minimized Average Structure within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn171

b:0.5
occ:1.00
NE2 A:HIS68 2.0 0.7 1.0
NE2 A:HIS83 2.1 0.5 1.0
ND1 A:HIS96 2.1 0.3 1.0
OD2 A:ASP70 2.2 2.3 1.0
CE1 A:HIS83 2.9 0.8 1.0
CD2 A:HIS68 2.9 0.6 1.0
HE1 A:HIS83 3.0 1.3 1.0
CE1 A:HIS96 3.0 0.3 1.0
HB2 A:HIS96 3.0 0.4 1.0
HD2 A:HIS68 3.1 0.7 1.0
CE1 A:HIS68 3.1 0.6 1.0
HE1 A:HIS96 3.1 0.4 1.0
CG A:HIS96 3.2 0.3 1.0
CG A:ASP70 3.3 1.5 1.0
CD2 A:HIS83 3.3 0.8 1.0
HE1 A:HIS68 3.4 0.7 1.0
CB A:HIS96 3.4 0.3 1.0
HB3 A:HIS96 3.5 0.4 1.0
HD2 A:HIS83 3.7 1.5 1.0
HE1 A:PHE85 3.7 0.4 1.0
HB2 A:ASP70 3.8 1.1 1.0
HG23 A:VAL64 3.9 1.1 1.0
HZ A:PHE85 3.9 0.5 1.0
CB A:ASP70 4.0 0.6 1.0
HB3 A:ASP70 4.0 1.1 1.0
CG A:HIS68 4.1 0.5 1.0
NE2 A:HIS96 4.1 0.3 1.0
ND1 A:HIS83 4.1 0.9 1.0
OD1 A:ASP70 4.1 2.2 1.0
ND1 A:HIS68 4.2 0.5 1.0
CD2 A:HIS96 4.2 0.2 1.0
CG A:HIS83 4.3 0.3 1.0
CE1 A:PHE85 4.4 0.4 1.0
CZ A:PHE85 4.5 0.4 1.0
HE2 A:PHE74 4.6 0.6 1.0
HG12 A:VAL64 4.8 1.0 1.0
CG2 A:VAL64 4.9 0.3 1.0
HZ A:PHE74 4.9 0.5 1.0
CA A:HIS96 4.9 0.2 1.0
HG22 A:VAL64 5.0 1.0 1.0
HD1 A:HIS83 5.0 1.6 1.0
HE2 A:HIS96 5.0 0.3 1.0

Reference:

F.J.Moy, P.K.Chanda, S.Cosmi, M.R.Pisano, C.Urbano, J.Wilhelm, R.Powers. High-Resolution Solution Structure of the Inhibitor-Free Catalytic Fragment of Human Fibroblast Collagenase Determined By Multidimensional uc(Nmr). Biochemistry V. 37 1495 1998.
ISSN: ISSN 0006-2960
PubMed: 9484219
DOI: 10.1021/BI972181W
Page generated: Wed Dec 16 03:17:58 2020

Last articles

Zn in 7RE3
Zn in 7RDX
Zn in 7RDZ
Zn in 7RWM
Zn in 7PGU
Zn in 7PGR
Zn in 7PGT
Zn in 7PGS
Zn in 7SQE
Zn in 7RWK
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy