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Atomistry » Zinc » PDB 2a25-2aer » 2a69 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 2a25-2aer » 2a69 » |
Zinc in PDB 2a69: Crystal Structure of the T. Thermophilus Rna Polymerase Holoenzyme in Complex with Antibiotic RifapentinEnzymatic activity of Crystal Structure of the T. Thermophilus Rna Polymerase Holoenzyme in Complex with Antibiotic Rifapentin
All present enzymatic activity of Crystal Structure of the T. Thermophilus Rna Polymerase Holoenzyme in Complex with Antibiotic Rifapentin:
2.7.7.6; Protein crystallography data
The structure of Crystal Structure of the T. Thermophilus Rna Polymerase Holoenzyme in Complex with Antibiotic Rifapentin, PDB code: 2a69
was solved by
I.Artsimovitch,
M.N.Vassylyeva,
D.Svetlov,
V.Svetlov,
A.Perederina,
N.Igarashi,
N.Matsugaki,
S.Wakatsuki,
T.H.Tahirov,
D.G.Vassylyev,
Riken Structural Genomics/Proteomicsinitiative (Rsgi),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2a69:
The structure of Crystal Structure of the T. Thermophilus Rna Polymerase Holoenzyme in Complex with Antibiotic Rifapentin also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of the T. Thermophilus Rna Polymerase Holoenzyme in Complex with Antibiotic Rifapentin
(pdb code 2a69). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of the T. Thermophilus Rna Polymerase Holoenzyme in Complex with Antibiotic Rifapentin, PDB code: 2a69: Jump to Zinc binding site number: 1; 2; 3; 4; Zinc binding site 1 out of 4 in 2a69Go back to Zinc Binding Sites List in 2a69
Zinc binding site 1 out
of 4 in the Crystal Structure of the T. Thermophilus Rna Polymerase Holoenzyme in Complex with Antibiotic Rifapentin
Mono view Stereo pair view
Zinc binding site 2 out of 4 in 2a69Go back to Zinc Binding Sites List in 2a69
Zinc binding site 2 out
of 4 in the Crystal Structure of the T. Thermophilus Rna Polymerase Holoenzyme in Complex with Antibiotic Rifapentin
Mono view Stereo pair view
Zinc binding site 3 out of 4 in 2a69Go back to Zinc Binding Sites List in 2a69
Zinc binding site 3 out
of 4 in the Crystal Structure of the T. Thermophilus Rna Polymerase Holoenzyme in Complex with Antibiotic Rifapentin
Mono view Stereo pair view
Zinc binding site 4 out of 4 in 2a69Go back to Zinc Binding Sites List in 2a69
Zinc binding site 4 out
of 4 in the Crystal Structure of the T. Thermophilus Rna Polymerase Holoenzyme in Complex with Antibiotic Rifapentin
Mono view Stereo pair view
Reference:
I.Artsimovitch,
M.N.Vassylyeva,
D.Svetlov,
V.Svetlov,
A.Perederina,
N.Igarashi,
N.Matsugaki,
S.Wakatsuki,
T.H.Tahirov,
D.G.Vassylyev.
Allosteric Modulation of the Rna Polymerase Catalytic Reaction Is An Essential Component of Transcription Control By Rifamycins. Cell(Cambridge,Mass.) V. 122 351 2005.
Page generated: Wed Dec 16 03:16:49 2020
ISSN: ISSN 0092-8674 PubMed: 16096056 DOI: 10.1016/J.CELL.2005.07.014 |
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