Zinc in PDB 2a0s: Crystal Structure of 6-Pyruvoyl Tetrahydropterin Synthase (Ptps) From Plasmodium Vivax at 2.2 A Resolution

All present enzymatic activity of Crystal Structure of 6-Pyruvoyl Tetrahydropterin Synthase (Ptps) From Plasmodium Vivax at 2.2 A Resolution:
4.2.3.12;

The structure of Crystal Structure of 6-Pyruvoyl Tetrahydropterin Synthase (Ptps) From Plasmodium Vivax at 2.2 A Resolution, PDB code: 2a0s was solved by J.Bosch, W.G.J.Hol, Structural Genomics Of Pathogenic Protozoaconsortium (Sgpp), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.20
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	132.095, 132.095, 74.126, 90.00, 90.00, 120.00
R / Rfree (%)	20.8 / 24.6

The binding sites of Zinc atom in the Crystal Structure of 6-Pyruvoyl Tetrahydropterin Synthase (Ptps) From Plasmodium Vivax at 2.2 A Resolution (pdb code 2a0s). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of 6-Pyruvoyl Tetrahydropterin Synthase (Ptps) From Plasmodium Vivax at 2.2 A Resolution, PDB code: 2a0s:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of 6-Pyruvoyl Tetrahydropterin Synthase (Ptps) From Plasmodium Vivax at 2.2 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of 6-Pyruvoyl Tetrahydropterin Synthase (Ptps) From Plasmodium Vivax at 2.2 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn281 b:35.4 occ:1.00 NE2 A:HIS50 2.1 24.4 1.0 NE2 A:HIS48 2.2 21.6 1.0 CE1 A:HIS36 2.4 20.0 1.0 O9 A:BIO282 2.5 57.3 1.0 OE2 A:GLU168 2.7 37.2 1.0 CD2 A:HIS50 2.9 23.8 1.0 NE2 A:HIS36 3.1 19.9 1.0 CD2 A:HIS48 3.1 21.5 1.0 CE1 A:HIS48 3.1 22.6 1.0 CE1 A:HIS50 3.2 22.8 1.0 C10 A:BIO282 3.3 58.9 1.0 C9 A:BIO282 3.4 57.8 1.0 CD A:GLU168 3.5 39.0 1.0 ND1 A:HIS36 3.5 22.0 1.0 O10 A:BIO282 3.6 60.1 1.0 OE2 A:GLU45 4.0 34.8 1.0 OE1 A:GLU168 4.1 40.4 1.0 CG A:HIS50 4.1 22.8 1.0 CG A:GLU168 4.2 38.2 1.0 ND1 A:HIS50 4.2 23.1 1.0 ND1 A:HIS48 4.2 22.6 1.0 CG A:HIS48 4.3 22.0 1.0 CD2 A:HIS36 4.3 20.1 1.0 CG A:HIS36 4.5 20.6 1.0 C6 A:BIO282 4.6 57.3 1.0 NE2 B:HIS87 4.7 34.4 1.0 N5 A:BIO282 4.7 57.0 1.0 C11 A:BIO282 4.7 59.7 1.0 O A:HOH294 4.8 18.1 1.0 OH A:TYR52 4.8 24.3 1.0 CE1 B:HIS87 4.8 34.0 1.0 CD A:GLU45 4.9 33.2 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of 6-Pyruvoyl Tetrahydropterin Synthase (Ptps) From Plasmodium Vivax at 2.2 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of 6-Pyruvoyl Tetrahydropterin Synthase (Ptps) From Plasmodium Vivax at 2.2 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn381 b:31.5 occ:1.00 O10 B:BIO382 2.8 69.5 0.8 C9 B:BIO382 3.8 67.8 0.8 C10 B:BIO382 3.9 68.9 0.8 O9 B:BIO382 4.4 68.5 0.8 C6 B:BIO382 4.9 67.5 0.8 N5 B:BIO382 4.9 67.3 0.8

J.Bosch, W.G.J.Hol, Structural Genomics Of Pathogenic Protozoa Consortium (Sgpp). Crystal Structure of 6-Pyruvoyl Tetrahydropterin Synthase (Ptps) From Plasmodium Vivax at 2.2 A Resolution To Be Published.