|
Atomistry » Zinc » PDB 1zs0-2a21 » 1zxv | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 1zs0-2a21 » 1zxv » |
Zinc in PDB 1zxv: X-Ray Crystal Structure of the Anthrax Lethal Factor Bound to A Small Molecule Inhibitor, Bi-MFM3, 3-{5-[5-(4-Chloro- Phenyl)-Furan-2-Ylmethylene]-4-Oxo-2-Thioxo-Thiazolidin-3- Yl}-Propionic Acid.Enzymatic activity of X-Ray Crystal Structure of the Anthrax Lethal Factor Bound to A Small Molecule Inhibitor, Bi-MFM3, 3-{5-[5-(4-Chloro- Phenyl)-Furan-2-Ylmethylene]-4-Oxo-2-Thioxo-Thiazolidin-3- Yl}-Propionic Acid.
All present enzymatic activity of X-Ray Crystal Structure of the Anthrax Lethal Factor Bound to A Small Molecule Inhibitor, Bi-MFM3, 3-{5-[5-(4-Chloro- Phenyl)-Furan-2-Ylmethylene]-4-Oxo-2-Thioxo-Thiazolidin-3- Yl}-Propionic Acid.:
3.4.24.83; Protein crystallography data
The structure of X-Ray Crystal Structure of the Anthrax Lethal Factor Bound to A Small Molecule Inhibitor, Bi-MFM3, 3-{5-[5-(4-Chloro- Phenyl)-Furan-2-Ylmethylene]-4-Oxo-2-Thioxo-Thiazolidin-3- Yl}-Propionic Acid., PDB code: 1zxv
was solved by
T.Y.Wong,
R.C.Liddington,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1zxv:
The structure of X-Ray Crystal Structure of the Anthrax Lethal Factor Bound to A Small Molecule Inhibitor, Bi-MFM3, 3-{5-[5-(4-Chloro- Phenyl)-Furan-2-Ylmethylene]-4-Oxo-2-Thioxo-Thiazolidin-3- Yl}-Propionic Acid. also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the X-Ray Crystal Structure of the Anthrax Lethal Factor Bound to A Small Molecule Inhibitor, Bi-MFM3, 3-{5-[5-(4-Chloro- Phenyl)-Furan-2-Ylmethylene]-4-Oxo-2-Thioxo-Thiazolidin-3- Yl}-Propionic Acid.
(pdb code 1zxv). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the X-Ray Crystal Structure of the Anthrax Lethal Factor Bound to A Small Molecule Inhibitor, Bi-MFM3, 3-{5-[5-(4-Chloro- Phenyl)-Furan-2-Ylmethylene]-4-Oxo-2-Thioxo-Thiazolidin-3- Yl}-Propionic Acid., PDB code: 1zxv: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 1zxvGo back to Zinc Binding Sites List in 1zxv
Zinc binding site 1 out
of 2 in the X-Ray Crystal Structure of the Anthrax Lethal Factor Bound to A Small Molecule Inhibitor, Bi-MFM3, 3-{5-[5-(4-Chloro- Phenyl)-Furan-2-Ylmethylene]-4-Oxo-2-Thioxo-Thiazolidin-3- Yl}-Propionic Acid.
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 1zxvGo back to Zinc Binding Sites List in 1zxv
Zinc binding site 2 out
of 2 in the X-Ray Crystal Structure of the Anthrax Lethal Factor Bound to A Small Molecule Inhibitor, Bi-MFM3, 3-{5-[5-(4-Chloro- Phenyl)-Furan-2-Ylmethylene]-4-Oxo-2-Thioxo-Thiazolidin-3- Yl}-Propionic Acid.
Mono view Stereo pair view
Reference:
M.Forino,
S.Johnson,
T.Y.Wong,
D.V.Rozanov,
A.Y.Savinov,
W.Li,
R.Fattorusso,
B.Becattini,
A.J.Orry,
D.Jung,
R.A.Abagyan,
J.W.Smith,
K.Alibek,
R.C.Liddington,
A.Y.Strongin,
M.Pellecchia.
Efficient Synthetic Inhibitors of Anthrax Lethal Factor. Proc.Natl.Acad.Sci.Usa V. 102 9499 2005.
Page generated: Wed Oct 16 21:24:59 2024
ISSN: ISSN 0027-8424 PubMed: 15983377 DOI: 10.1073/PNAS.0502733102 |
Last articlesZn in 9JYWZn in 9IR4 Zn in 9IR3 Zn in 9GMX Zn in 9GMW Zn in 9JEJ Zn in 9ERF Zn in 9ERE Zn in 9EGV Zn in 9EGW |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |