Zinc in PDB 1zud: Structure of This-Thif Protein Complex

The structure of Structure of This-Thif Protein Complex, PDB code: 1zud was solved by S.E.Ealick, C.Lehmann, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.23 / 1.98
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	49.505, 111.171, 114.153, 90.00, 90.00, 90.00
R / Rfree (%)	17.4 / 22.9

The structure of Structure of This-Thif Protein Complex also contains other interesting chemical elements:

Calcium	(Ca)	2 atoms
Sodium	(Na)	2 atoms

The binding sites of Zinc atom in the Structure of This-Thif Protein Complex (pdb code 1zud). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of This-Thif Protein Complex, PDB code: 1zud:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of This-Thif Protein Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of This-Thif Protein Complex within 5.0Å range: probe atom residue distance (Å) B Occ 1:Zn501 b:28.4 occ:1.00 SG 1:CYS172 2.3 24.5 1.0 SG 1:CYS169 2.3 25.5 1.0 SG 1:CYS240 2.3 26.1 1.0 SG 1:CYS243 2.4 26.8 1.0 CB 1:CYS240 3.2 24.7 1.0 CB 1:CYS169 3.4 23.8 1.0 N 1:CYS169 3.4 23.0 1.0 N 1:CYS172 3.5 27.8 1.0 CB 1:CYS172 3.5 28.2 1.0 CB 1:CYS243 3.6 24.6 1.0 N 1:CYS243 3.8 24.1 1.0 CA 1:CYS172 3.9 30.5 1.0 CA 1:CYS169 3.9 24.1 1.0 CA 1:CYS243 4.2 22.8 1.0 C 1:ARG171 4.3 30.8 1.0 C 1:GLY168 4.3 25.0 1.0 C 1:CYS169 4.4 23.3 1.0 CB 1:ARG171 4.5 30.3 0.5 CA 1:GLY168 4.5 18.4 1.0 O 1:HOH703 4.6 27.0 1.0 CB 1:ARG171 4.6 27.6 0.5 O 1:CYS169 4.6 22.5 1.0 CA 1:CYS240 4.6 29.4 1.0 CB 1:VAL242 4.7 27.3 1.0 N 1:ARG171 4.7 26.9 1.0 CA 1:ARG171 4.7 26.8 1.0 C 1:CYS243 4.7 22.3 1.0 C 1:VAL242 4.9 28.5 1.0 CG 1:ARG171 4.9 43.0 0.5 N 1:GLY244 4.9 27.0 1.0

Zinc binding site 2 out of 2 in the Structure of This-Thif Protein Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of This-Thif Protein Complex within 5.0Å range: probe atom residue distance (Å) B Occ 3:Zn502 b:28.1 occ:1.00 SG 3:CYS240 2.2 28.1 1.0 SG 3:CYS172 2.3 26.2 1.0 SG 3:CYS169 2.4 23.9 1.0 SG 3:CYS243 2.4 30.1 1.0 CB 3:CYS240 3.0 29.8 1.0 N 3:CYS169 3.4 25.8 1.0 CB 3:CYS169 3.5 18.5 1.0 CB 3:CYS243 3.5 20.5 1.0 N 3:CYS172 3.6 24.4 1.0 CB 3:CYS172 3.6 22.8 1.0 N 3:CYS243 3.8 24.0 1.0 CA 3:CYS172 3.9 23.3 1.0 CA 3:CYS169 4.0 24.6 1.0 CA 3:CYS243 4.2 29.0 1.0 C 3:GLY168 4.3 27.0 1.0 C 3:ARG171 4.3 26.3 1.0 C 3:CYS169 4.4 21.7 1.0 CA 3:GLY168 4.4 23.7 1.0 O 3:HOH812 4.5 34.0 1.0 CA 3:CYS240 4.5 29.9 1.0 O 3:CYS169 4.5 23.6 1.0 CB 3:ARG171 4.6 29.4 1.0 CB 3:VAL242 4.7 26.0 1.0 C 3:CYS243 4.8 30.8 1.0 CA 3:ARG171 4.8 27.2 1.0 N 3:ARG171 4.8 23.6 1.0 C 3:VAL242 4.9 23.8 1.0 N 3:GLY244 4.9 33.0 1.0 CG 3:ARG171 5.0 35.1 1.0

C.Lehmann, T.P.Begley, S.E.Ealick. Structure of the Escherichia Coli This-Thif Complex, A Key Component of the Sulfur Transfer System in Thiamin Biosynthesis. Biochemistry V. 45 11 2006.
ISSN: ISSN 0006-2960
PubMed: 16388576
DOI: 10.1021/BI051502Y