|
Atomistry » Zinc » PDB 1xm6-1xug » 1xot | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 1xm6-1xug » 1xot » |
Zinc in PDB 1xot: Catalytic Domain of Human Phosphodiesterase 4B in Complex with VardenafilEnzymatic activity of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Vardenafil
All present enzymatic activity of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Vardenafil:
3.1.4.17; Protein crystallography data
The structure of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Vardenafil, PDB code: 1xot
was solved by
G.L.Card,
B.P.England,
Y.Suzuki,
D.Fong,
B.Powell,
B.Lee,
C.Luu,
M.Tabrizizad,
S.Gillette,
P.N.Ibrahim,
D.R.Artis,
G.Bollag,
M.V.Milburn,
S.-H.Kim,
J.Schlessinger,
K.Y.J.Zhang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1xot:
The structure of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Vardenafil also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Vardenafil
(pdb code 1xot). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Vardenafil, PDB code: 1xot: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 1xotGo back to Zinc Binding Sites List in 1xot
Zinc binding site 1 out
of 2 in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Vardenafil
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 1xotGo back to Zinc Binding Sites List in 1xot
Zinc binding site 2 out
of 2 in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Vardenafil
Mono view Stereo pair view
Reference:
G.L.Card,
B.P.England,
Y.Suzuki,
D.Fong,
B.Powell,
B.Lee,
C.Luu,
M.Tabrizizad,
S.Gillette,
P.N.Ibrahim,
D.R.Artis,
G.Bollag,
M.V.Milburn,
S.-H.Kim,
J.Schlessinger,
K.Y.J.Zhang.
Structural Basis For the Activity of Drugs That Inhibit Phosphodiesterases. Structure V. 12 2233 2004.
Page generated: Wed Dec 16 03:12:54 2020
ISSN: ISSN 0969-2126 PubMed: 15576036 DOI: 10.1016/J.STR.2004.10.004 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |