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Atomistry » Zinc » PDB 1x81-1xm4 » 1xlx | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 1x81-1xm4 » 1xlx » |
Zinc in PDB 1xlx: Catalytic Domain of Human Phosphodiesterase 4B in Complex with CilomilastEnzymatic activity of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Cilomilast
All present enzymatic activity of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Cilomilast:
3.1.4.17; Protein crystallography data
The structure of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Cilomilast, PDB code: 1xlx
was solved by
G.L.Card,
B.P.England,
Y.Suzuki,
D.Fong,
B.Powell,
B.Lee,
C.Luu,
M.Tabrizizad,
S.Gillette,
P.N.Ibrahim,
D.R.Artis,
G.Bollag,
M.V.Milburn,
S.-H.Kim,
J.Schlessinger,
K.Y.J.Zhang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1xlx:
The structure of Catalytic Domain of Human Phosphodiesterase 4B in Complex with Cilomilast also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Cilomilast
(pdb code 1xlx). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Cilomilast, PDB code: 1xlx: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 1xlxGo back to Zinc Binding Sites List in 1xlx
Zinc binding site 1 out
of 2 in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Cilomilast
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 1xlxGo back to Zinc Binding Sites List in 1xlx
Zinc binding site 2 out
of 2 in the Catalytic Domain of Human Phosphodiesterase 4B in Complex with Cilomilast
Mono view Stereo pair view
Reference:
G.L.Card,
B.P.England,
Y.Suzuki,
D.Fong,
B.Powell,
B.Lee,
C.Luu,
M.Tabrizizad,
S.Gillette,
P.N.Ibrahim,
D.R.Artis,
G.Bollag,
M.V.Milburn,
S.-H.Kim,
J.Schlessinger,
K.Y.J.Zhang.
Structural Basis For the Activity of Drugs That Inhibit Phosphodiesterases. Structure V. 12 2233 2004.
Page generated: Wed Dec 16 03:12:28 2020
ISSN: ISSN 0969-2126 PubMed: 15576036 DOI: 10.1016/J.STR.2004.10.004 |
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