Zinc in PDB 2gc2: The Crystal Structure of Phosphoglucose Isomerase From Pyrococcus Furiosus in Complex with Fructose 6-Phosphate and Zinc

All present enzymatic activity of The Crystal Structure of Phosphoglucose Isomerase From Pyrococcus Furiosus in Complex with Fructose 6-Phosphate and Zinc:
5.3.1.9;

The structure of The Crystal Structure of Phosphoglucose Isomerase From Pyrococcus Furiosus in Complex with Fructose 6-Phosphate and Zinc, PDB code: 2gc2 was solved by J.M.Berrisford, D.W.Rice, P.J.Baker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.76 / 2.10
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	70.067, 73.945, 74.392, 90.00, 90.00, 90.00
R / Rfree (%)	17.2 / 24.6

The binding sites of Zinc atom in the The Crystal Structure of Phosphoglucose Isomerase From Pyrococcus Furiosus in Complex with Fructose 6-Phosphate and Zinc (pdb code 2gc2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the The Crystal Structure of Phosphoglucose Isomerase From Pyrococcus Furiosus in Complex with Fructose 6-Phosphate and Zinc, PDB code: 2gc2:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the The Crystal Structure of Phosphoglucose Isomerase From Pyrococcus Furiosus in Complex with Fructose 6-Phosphate and Zinc


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Crystal Structure of Phosphoglucose Isomerase From Pyrococcus Furiosus in Complex with Fructose 6-Phosphate and Zinc within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:22.2 occ:1.00 OE2 A:GLU97 2.1 23.2 1.0 NE2 A:HIS136 2.2 17.1 1.0 NE2 A:HIS88 2.2 21.9 1.0 O1 A:F6R501 2.3 11.6 0.5 NE2 A:HIS90 2.3 16.3 1.0 O2 A:F6R501 2.6 21.8 1.0 CE1 A:HIS88 3.1 22.6 1.0 CD2 A:HIS90 3.1 15.3 1.0 CD A:GLU97 3.1 24.8 1.0 CE1 A:HIS136 3.1 16.2 1.0 CD2 A:HIS136 3.2 16.1 1.0 C1 A:F6R501 3.2 21.9 0.5 CD2 A:HIS88 3.3 20.9 1.0 C1 A:F6R501 3.3 25.9 0.5 CE1 A:HIS90 3.3 18.3 1.0 C2 A:F6R501 3.4 26.6 1.0 OE1 A:GLU97 3.4 26.9 1.0 ND1 A:HIS88 4.2 23.1 1.0 ND1 A:HIS136 4.2 15.4 1.0 CG A:HIS90 4.3 18.3 1.0 CG A:HIS136 4.3 13.8 1.0 CG A:HIS88 4.3 21.9 1.0 ND1 A:HIS90 4.4 17.6 1.0 O A:HOH522 4.4 19.2 1.0 CG A:GLU97 4.4 18.4 1.0 O1 A:F6R501 4.5 24.1 0.5 CB A:GLU97 4.7 16.3 1.0 OH A:TYR99 4.8 20.1 1.0 C3 A:F6R501 4.8 30.3 1.0 CD2 A:HIS158 4.9 30.8 1.0 NE2 A:HIS158 5.0 32.2 1.0

Zinc binding site 2 out of 2 in the The Crystal Structure of Phosphoglucose Isomerase From Pyrococcus Furiosus in Complex with Fructose 6-Phosphate and Zinc


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Crystal Structure of Phosphoglucose Isomerase From Pyrococcus Furiosus in Complex with Fructose 6-Phosphate and Zinc within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn402 b:32.1 occ:1.00 NE2 B:HIS90 2.2 30.5 1.0 OE2 B:GLU97 2.3 26.9 1.0 NE2 B:HIS136 2.3 25.0 1.0 O1 B:F6R502 2.3 21.8 0.5 NE2 B:HIS88 2.5 32.4 1.0 O2 B:F6R502 2.7 34.0 1.0 CE1 B:HIS136 3.0 21.3 1.0 CD2 B:HIS90 3.0 27.7 1.0 CD2 B:HIS88 3.3 32.0 1.0 CE1 B:HIS90 3.4 30.3 1.0 C1 B:F6R502 3.4 34.1 0.5 CD B:GLU97 3.4 28.9 1.0 CE1 B:HIS88 3.5 31.7 1.0 CD2 B:HIS136 3.5 23.1 1.0 C2 B:F6R502 3.6 36.0 1.0 C1 B:F6R502 3.7 36.4 0.5 OE1 B:GLU97 3.9 34.0 1.0 O B:HOH584 4.2 28.4 1.0 ND1 B:HIS136 4.2 21.4 1.0 CG B:HIS90 4.2 27.5 1.0 O1 B:F6R502 4.3 31.8 0.5 ND1 B:HIS90 4.3 31.2 1.0 CG B:HIS88 4.5 29.3 1.0 CG B:HIS136 4.5 21.6 1.0 ND1 B:HIS88 4.5 31.9 1.0 CG B:GLU97 4.7 24.3 1.0 OH B:TYR99 4.7 22.5 1.0 CB B:GLU97 4.8 18.0 1.0 CD2 B:HIS158 4.9 41.8 1.0 C3 B:F6R502 5.0 38.2 1.0 NE2 B:HIS158 5.0 42.2 1.0

J.M.Berrisford, A.M.Hounslow, J.Akerboom, W.R.Hagen, S.J.Brouns, J.Van Der Oost, I.A.Murray, G.Michael Blackburn, J.P.Waltho, D.W.Rice, P.J.Baker. Evidence Supporting A Cis-Enediol-Based Mechanism For Pyrococcus Furiosus Phosphoglucose Isomerase J.Mol.Biol. V. 358 1353 2006.
ISSN: ISSN 0022-2836
PubMed: 16580686
DOI: 10.1016/J.JMB.2006.03.015