Zinc in PDB 2z7w: Crystal Structure of H2O2 Treated Cu,Zn-Sod

All present enzymatic activity of Crystal Structure of H2O2 Treated Cu,Zn-Sod:
1.15.1.1;

The structure of Crystal Structure of H2O2 Treated Cu,Zn-Sod, PDB code: 2z7w was solved by S.Ito, T.Ishii, K.Uchida, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.07 / 1.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	45.085, 50.714, 149.341, 90.00, 90.00, 90.00
R / Rfree (%)	21 / 23.4

The structure of Crystal Structure of H2O2 Treated Cu,Zn-Sod also contains other interesting chemical elements:

Copper

(Cu)

2 atoms

The binding sites of Zinc atom in the Crystal Structure of H2O2 Treated Cu,Zn-Sod (pdb code 2z7w). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of H2O2 Treated Cu,Zn-Sod, PDB code: 2z7w:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of H2O2 Treated Cu,Zn-Sod


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of H2O2 Treated Cu,Zn-Sod within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn300 b:45.1 occ:1.00 ND1 A:HIS61 2.1 45.7 1.0 OD1 A:ASP81 2.1 36.9 1.0 ND1 A:HIS78 2.3 41.1 1.0 ND1 A:HIS69 2.4 50.1 1.0 CG A:ASP81 3.0 38.0 1.0 CE1 A:HIS61 3.0 45.8 1.0 CG A:HIS61 3.1 44.7 1.0 CE1 A:HIS78 3.1 41.1 1.0 OD2 A:ASP81 3.3 38.7 1.0 CE1 A:HIS69 3.3 51.2 1.0 CG A:HIS78 3.3 40.6 1.0 CG A:HIS69 3.4 50.0 1.0 CB A:HIS61 3.4 43.5 1.0 CB A:HIS78 3.7 39.5 1.0 CB A:HIS69 3.7 49.1 1.0 O A:LYS134 4.0 75.6 1.0 CA A:HIS69 4.1 47.9 1.0 NE2 A:HIS61 4.2 46.7 1.0 CD2 A:HIS61 4.2 45.7 1.0 NE2 A:HIS78 4.3 42.0 1.0 CD2 A:HIS78 4.4 41.3 1.0 CB A:ASP81 4.4 37.7 1.0 NE2 A:HIS69 4.4 50.9 1.0 CD2 A:HIS69 4.5 50.1 1.0 O A:HOH312 4.7 56.4 1.0 CA A:ASP81 4.8 37.1 1.0 C A:LYS134 4.8 75.7 1.0 N A:GLY70 4.9 48.2 1.0 N A:ASP81 4.9 36.9 1.0 N A:HIS78 4.9 40.4 1.0 CD2 A:HIS44 4.9 44.6 1.0 CA A:HIS78 4.9 39.8 1.0 CA A:HIS61 5.0 41.1 1.0 CA A:THR135 5.0 72.1 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of H2O2 Treated Cu,Zn-Sod


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of H2O2 Treated Cu,Zn-Sod within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn300 b:21.0 occ:1.00 OD1 B:ASP81 2.0 16.4 1.0 ND1 B:HIS61 2.1 20.6 1.0 ND1 B:HIS69 2.1 18.2 1.0 ND1 B:HIS78 2.1 19.3 1.0 CG B:ASP81 2.8 17.3 1.0 OD2 B:ASP81 2.9 19.4 1.0 CE1 B:HIS69 3.0 18.2 1.0 CE1 B:HIS61 3.0 23.9 1.0 CE1 B:HIS78 3.0 18.9 1.0 CG B:HIS61 3.1 21.9 1.0 CG B:HIS78 3.2 18.6 1.0 CG B:HIS69 3.3 18.3 1.0 CB B:HIS61 3.4 21.3 1.0 CB B:HIS78 3.5 16.2 1.0 CB B:HIS69 3.7 18.6 1.0 O B:LYS134 3.7 20.6 1.0 CA B:HIS69 4.0 18.9 1.0 NE2 B:HIS61 4.1 26.6 1.0 NE2 B:HIS69 4.2 17.7 1.0 NE2 B:HIS78 4.2 17.6 1.0 CB B:ASP81 4.2 17.9 1.0 CD2 B:HIS61 4.2 25.1 1.0 CD2 B:HIS78 4.2 18.1 1.0 CD2 B:HIS69 4.3 19.3 1.0 C B:LYS134 4.7 21.2 1.0 CA B:ASP81 4.7 18.6 1.0 N B:HIS78 4.7 19.8 1.0 O B:HOH322 4.7 29.5 1.0 CA B:HIS78 4.8 18.2 1.0 N B:GLY70 4.8 19.4 1.0 N B:ASP81 4.9 20.1 1.0 N B:HIS69 5.0 20.0 1.0 CA B:HIS61 5.0 21.3 1.0 C B:HIS69 5.0 19.1 1.0

S.Ito, T.Ishii, K.Uchida. Crystal Structures of H2O2-Treated Cu,Zn-Superoxide Dismutase To Be Published.