Zinc in PDB 1umt: Stromelysin-1 Catalytic Domain with Hydrophobic Inhibitor Bound, pH 7.0, 32OC, 20 Mm CACL2, 15% Acetonitrile; uc(Nmr) Average of 20 Structures Minimized with Restraints

Enzymatic activity of Stromelysin-1 Catalytic Domain with Hydrophobic Inhibitor Bound, pH 7.0, 32OC, 20 Mm CACL2, 15% Acetonitrile; uc(Nmr) Average of 20 Structures Minimized with Restraints

Other elements in 1umt:

Zinc Binding Sites:

Zinc binding site 1 out of 2 in 1umt

Zinc Binding Sites List in 1umt

Zinc binding site 1 out of 2 in the Stromelysin-1 Catalytic Domain with Hydrophobic Inhibitor Bound, pH 7.0, 32OC, 20 Mm CACL2, 15% Acetonitrile; uc(Nmr) Average of 20 Structures Minimized with Restraints


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Stromelysin-1 Catalytic Domain with Hydrophobic Inhibitor Bound, pH 7.0, 32OC, 20 Mm CACL2, 15% Acetonitrile; uc(Nmr) Average of 20 Structures Minimized with Restraints within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1 b:0.0 occ:1.00 O21 A:0DS261 2.3 0.0 1.0 O3 A:0DS261 2.3 0.0 1.0 NE2 A:HIS201 2.3 0.0 1.0 NE2 A:HIS205 2.3 0.0 1.0 NE2 A:HIS211 2.3 0.0 1.0 HO A:0DS261 2.6 0.0 1.0 HE1 A:HIS205 2.7 0.0 1.0 CE1 A:HIS205 2.9 0.0 1.0 CD2 A:HIS211 2.9 0.0 1.0 C21 A:0DS261 2.9 0.0 1.0 N3 A:0DS261 3.0 0.0 1.0 HH A:TYR155 3.0 0.0 1.0 CE1 A:HIS211 3.1 0.0 1.0 HE2 A:TYR155 3.1 0.0 1.0 CD2 A:HIS201 3.1 0.0 1.0 HD2 A:HIS211 3.2 0.0 1.0 HD2 A:HIS201 3.3 0.0 1.0 CE1 A:HIS201 3.4 0.0 1.0 HE1 A:HIS211 3.4 0.0 1.0 CD2 A:HIS205 3.6 0.0 1.0 HE1 A:HIS201 3.7 0.0 1.0 CG A:HIS211 3.8 0.0 1.0 ND1 A:HIS211 3.9 0.0 1.0 HN A:0DS261 3.9 0.0 1.0 OH A:TYR155 4.0 0.0 1.0 HD2 A:HIS205 4.1 0.0 1.0 CE2 A:TYR155 4.1 0.0 1.0 ND1 A:HIS205 4.2 0.0 1.0 CG A:HIS201 4.3 0.0 1.0 H A:HIS211 4.4 0.0 1.0 C11 A:0DS261 4.4 0.0 1.0 HA A:HIS211 4.4 0.0 1.0 CG A:HIS205 4.4 0.0 1.0 ND1 A:HIS201 4.5 0.0 1.0 CZ A:TYR155 4.5 0.0 1.0 HE2 A:PHE154 4.6 0.0 1.0 H13 A:0DS261 4.7 0.0 1.0 O1 A:0DS261 4.8 0.0 1.0 N A:HIS211 4.9 0.0 1.0 CB A:HIS211 5.0 0.0 1.0 H32 A:0DS261 5.0 0.0 1.0 HE1 A:MET219 5.0 0.0 1.0

Zinc binding site 2 out of 2 in 1umt

Zinc Binding Sites List in 1umt

Zinc binding site 2 out of 2 in the Stromelysin-1 Catalytic Domain with Hydrophobic Inhibitor Bound, pH 7.0, 32OC, 20 Mm CACL2, 15% Acetonitrile; uc(Nmr) Average of 20 Structures Minimized with Restraints


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Stromelysin-1 Catalytic Domain with Hydrophobic Inhibitor Bound, pH 7.0, 32OC, 20 Mm CACL2, 15% Acetonitrile; uc(Nmr) Average of 20 Structures Minimized with Restraints within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2 b:0.0 occ:1.00 OD2 A:ASP153 2.3 0.0 1.0 ND1 A:HIS179 2.3 0.0 1.0 NE2 A:HIS151 2.3 0.0 1.0 NE2 A:HIS166 2.3 0.0 1.0 HE1 A:HIS166 2.5 0.0 1.0 CE1 A:HIS166 2.6 0.0 1.0 CD2 A:HIS151 2.7 0.0 1.0 CG A:HIS179 2.7 0.0 1.0 CE1 A:HIS151 2.7 0.0 1.0 CE1 A:HIS179 2.9 0.0 1.0 HB2 A:ALA147 2.9 0.0 1.0 HB2 A:HIS179 2.9 0.0 1.0 CG A:HIS151 3.1 0.0 1.0 CB A:HIS179 3.2 0.0 1.0 HD2 A:HIS151 3.2 0.0 1.0 HE1 A:HIS151 3.3 0.0 1.0 ND1 A:HIS151 3.3 0.0 1.0 HB3 A:HIS179 3.3 0.0 1.0 CD2 A:HIS179 3.3 0.0 1.0 HE1 A:HIS179 3.4 0.0 1.0 CG A:ASP153 3.4 0.0 1.0 NE2 A:HIS179 3.4 0.0 1.0 CD2 A:HIS166 3.5 0.0 1.0 ND1 A:HIS166 3.6 0.0 1.0 HB2 A:ASP153 3.9 0.0 1.0 HB3 A:HIS151 3.9 0.0 1.0 CB A:ALA147 3.9 0.0 1.0 CG A:HIS166 4.0 0.0 1.0 CB A:HIS151 4.1 0.0 1.0 HD2 A:HIS179 4.1 0.0 1.0 HB3 A:ALA147 4.1 0.0 1.0 CB A:ASP153 4.2 0.0 1.0 HE2 A:HIS179 4.2 0.0 1.0 HD2 A:HIS166 4.2 0.0 1.0 HB3 A:ASP153 4.3 0.0 1.0 OD1 A:ASP153 4.3 0.0 1.0 HB2 A:HIS151 4.3 0.0 1.0 HB1 A:ALA147 4.4 0.0 1.0 O A:HIS166 4.4 0.0 1.0 HA A:VAL148 4.6 0.0 1.0 CA A:HIS179 4.7 0.0 1.0 C A:ALA147 4.8 0.0 1.0 CA A:ALA147 4.9 0.0 1.0 O A:ALA147 5.0 0.0 1.0

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