Zinc in PDB 1ums: Stromelysin-1 Catalytic Domain with Hydrophobic Inhibitor Bound, pH 7.0, 32OC, 20 Mm CACL2, 15% Acetonitrile; uc(Nmr) Ensemble of 20 Structures

Enzymatic activity of Stromelysin-1 Catalytic Domain with Hydrophobic Inhibitor Bound, pH 7.0, 32OC, 20 Mm CACL2, 15% Acetonitrile; uc(Nmr) Ensemble of 20 Structures

Other elements in 1ums:

Zinc Binding Sites:

Zinc binding site 1 out of 2 in 1ums

Zinc Binding Sites List in 1ums

Zinc binding site 1 out of 2 in the Stromelysin-1 Catalytic Domain with Hydrophobic Inhibitor Bound, pH 7.0, 32OC, 20 Mm CACL2, 15% Acetonitrile; uc(Nmr) Ensemble of 20 Structures


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Stromelysin-1 Catalytic Domain with Hydrophobic Inhibitor Bound, pH 7.0, 32OC, 20 Mm CACL2, 15% Acetonitrile; uc(Nmr) Ensemble of 20 Structures within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1 b:0.0 occ:1.00 O2 A:HAE261 2.3 0.0 1.0 O A:HAE261 2.3 0.0 1.0 NE2 A:HIS201 2.3 0.0 1.0 NE2 A:HIS211 2.3 0.0 1.0 NE2 A:HIS205 2.3 0.0 1.0 HH A:TYR155 2.4 0.0 1.0 HE1 A:HIS205 2.8 0.0 1.0 CE1 A:HIS205 2.9 0.0 1.0 CD2 A:HIS211 2.9 0.0 1.0 CD2 A:HIS201 3.0 0.0 1.0 HD2 A:HIS201 3.0 0.0 1.0 HO A:HAE261 3.0 0.0 1.0 C2 A:HAE261 3.0 0.0 1.0 N A:HAE261 3.1 0.0 1.0 HD2 A:HIS211 3.1 0.0 1.0 OH A:TYR155 3.1 0.0 1.0 CE1 A:HIS211 3.3 0.0 1.0 CE1 A:HIS201 3.5 0.0 1.0 CD2 A:HIS205 3.5 0.0 1.0 HE1 A:HIS211 3.7 0.0 1.0 HE2 A:TYR155 3.8 0.0 1.0 HE1 A:HIS201 3.9 0.0 1.0 HN A:HAE261 4.0 0.0 1.0 CG A:HIS211 4.0 0.0 1.0 HD2 A:HIS205 4.1 0.0 1.0 ND1 A:HIS205 4.1 0.0 1.0 CZ A:TYR155 4.2 0.0 1.0 CG A:HIS201 4.2 0.0 1.0 H31 A:MOP257 4.2 0.0 1.0 ND1 A:HIS211 4.3 0.0 1.0 CG A:HIS205 4.4 0.0 1.0 CE2 A:TYR155 4.4 0.0 1.0 C1 A:HAE261 4.5 0.0 1.0 ND1 A:HIS201 4.5 0.0 1.0 H A:HIS211 4.7 0.0 1.0 HA A:HIS211 4.7 0.0 1.0 H12 A:HAE261 4.7 0.0 1.0 HE3 A:MET219 4.8 0.0 1.0 HE1 A:MET219 4.8 0.0 1.0

Zinc binding site 2 out of 2 in 1ums

Zinc Binding Sites List in 1ums

Zinc binding site 2 out of 2 in the Stromelysin-1 Catalytic Domain with Hydrophobic Inhibitor Bound, pH 7.0, 32OC, 20 Mm CACL2, 15% Acetonitrile; uc(Nmr) Ensemble of 20 Structures


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Stromelysin-1 Catalytic Domain with Hydrophobic Inhibitor Bound, pH 7.0, 32OC, 20 Mm CACL2, 15% Acetonitrile; uc(Nmr) Ensemble of 20 Structures within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2 b:0.0 occ:1.00 OD2 A:ASP153 2.3 0.0 1.0 ND1 A:HIS179 2.3 0.0 1.0 NE2 A:HIS151 2.3 0.0 1.0 NE2 A:HIS166 2.3 0.0 1.0 HB2 A:ASP153 2.4 0.0 1.0 CD2 A:HIS151 2.7 0.0 1.0 CG A:HIS179 2.7 0.0 1.0 CE1 A:HIS151 2.8 0.0 1.0 CE1 A:HIS179 2.9 0.0 1.0 CE1 A:HIS166 2.9 0.0 1.0 HB2 A:HIS179 3.0 0.0 1.0 HD2 A:HIS151 3.1 0.0 1.0 CG A:ASP153 3.1 0.0 1.0 CG A:HIS151 3.2 0.0 1.0 HE1 A:HIS166 3.2 0.0 1.0 CB A:ASP153 3.2 0.0 1.0 CD2 A:HIS179 3.2 0.0 1.0 CB A:HIS179 3.2 0.0 1.0 CD2 A:HIS166 3.3 0.0 1.0 HE1 A:HIS151 3.4 0.0 1.0 ND1 A:HIS151 3.4 0.0 1.0 HB3 A:HIS179 3.4 0.0 1.0 NE2 A:HIS179 3.4 0.0 1.0 HB3 A:ASP153 3.4 0.0 1.0 HE1 A:HIS179 3.4 0.0 1.0 HB3 A:HIS151 3.8 0.0 1.0 ND1 A:HIS166 3.8 0.0 1.0 CG A:HIS166 3.9 0.0 1.0 HB A:VAL148 3.9 0.0 1.0 HD2 A:HIS179 3.9 0.0 1.0 HD2 A:HIS166 4.0 0.0 1.0 CB A:HIS151 4.1 0.0 1.0 HE2 A:HIS179 4.2 0.0 1.0 O A:HIS166 4.2 0.0 1.0 HE1 A:TYR168 4.3 0.0 1.0 HB1 A:ALA147 4.3 0.0 1.0 OD1 A:ASP153 4.4 0.0 1.0 HH A:TYR168 4.4 0.0 1.0 CA A:ASP153 4.5 0.0 1.0 H A:ASP153 4.5 0.0 1.0 HB2 A:HIS151 4.6 0.0 1.0 N A:ASP153 4.7 0.0 1.0 CA A:HIS179 4.7 0.0 1.0 HA A:ASP153 4.8 0.0 1.0 CB A:VAL148 4.9 0.0 1.0 HG22 A:VAL148 4.9 0.0 1.0 H A:HIS179 4.9 0.0 1.0 HG21 A:VAL148 4.9 0.0 1.0 HB2 A:ALA147 5.0 0.0 1.0

Reference: