Zinc in PDB 1u2n: Structure Cbp TAZ1 Domain
Enzymatic activity of Structure Cbp TAZ1 Domain
All present enzymatic activity of Structure Cbp TAZ1 Domain:
2.3.1.48;
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure Cbp TAZ1 Domain
(pdb code 1u2n). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the
Structure Cbp TAZ1 Domain, PDB code: 1u2n:
Jump to Zinc binding site number:
1;
2;
3;
Zinc binding site 1 out
of 3 in 1u2n
Go back to
Zinc Binding Sites List in 1u2n
Zinc binding site 1 out
of 3 in the Structure Cbp TAZ1 Domain
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Structure Cbp TAZ1 Domain within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn440
b:0.0
occ:1.00
|
NE2
|
A:HIS362
|
2.1
|
0.0
|
1.0
|
SG
|
A:CYS384
|
2.3
|
0.0
|
1.0
|
SG
|
A:CYS379
|
2.3
|
0.0
|
1.0
|
SG
|
A:CYS366
|
2.3
|
0.0
|
1.0
|
CD2
|
A:HIS362
|
2.8
|
0.0
|
1.0
|
HD2
|
A:HIS362
|
2.8
|
0.0
|
1.0
|
HB2
|
A:CYS366
|
3.1
|
0.0
|
1.0
|
HB2
|
A:CYS379
|
3.1
|
0.0
|
1.0
|
CB
|
A:CYS366
|
3.2
|
0.0
|
1.0
|
CB
|
A:CYS379
|
3.2
|
0.0
|
1.0
|
HB3
|
A:CYS366
|
3.3
|
0.0
|
1.0
|
HE2
|
A:LYS388
|
3.3
|
0.0
|
1.0
|
HB3
|
A:CYS379
|
3.3
|
0.0
|
1.0
|
CE1
|
A:HIS362
|
3.3
|
0.0
|
1.0
|
HH11
|
A:ARG369
|
3.4
|
0.0
|
1.0
|
HH12
|
A:ARG369
|
3.5
|
0.0
|
1.0
|
CB
|
A:CYS384
|
3.5
|
0.0
|
1.0
|
HB2
|
A:CYS384
|
3.5
|
0.0
|
1.0
|
HE3
|
A:LYS388
|
3.6
|
0.0
|
1.0
|
HB3
|
A:CYS384
|
3.7
|
0.0
|
1.0
|
HE1
|
A:HIS362
|
3.8
|
0.0
|
1.0
|
NH1
|
A:ARG369
|
3.8
|
0.0
|
1.0
|
CE
|
A:LYS388
|
4.0
|
0.0
|
1.0
|
CG
|
A:HIS362
|
4.1
|
0.0
|
1.0
|
HB3
|
A:LEU381
|
4.2
|
0.0
|
1.0
|
ND1
|
A:HIS362
|
4.3
|
0.0
|
1.0
|
HZ2
|
A:LYS388
|
4.5
|
0.0
|
1.0
|
CA
|
A:CYS379
|
4.6
|
0.0
|
1.0
|
CA
|
A:CYS366
|
4.6
|
0.0
|
1.0
|
H
|
A:LEU381
|
4.7
|
0.0
|
1.0
|
O
|
A:HIS362
|
4.8
|
0.0
|
1.0
|
HA
|
A:CYS379
|
4.8
|
0.0
|
1.0
|
HD2
|
A:LYS388
|
4.8
|
0.0
|
1.0
|
HB2
|
A:LEU381
|
4.8
|
0.0
|
1.0
|
HA
|
A:ALA363
|
4.8
|
0.0
|
1.0
|
HA
|
A:CYS366
|
4.8
|
0.0
|
1.0
|
CA
|
A:CYS384
|
4.9
|
0.0
|
1.0
|
NZ
|
A:LYS388
|
4.9
|
0.0
|
1.0
|
HD11
|
A:LEU381
|
4.9
|
0.0
|
1.0
|
|
Zinc binding site 2 out
of 3 in 1u2n
Go back to
Zinc Binding Sites List in 1u2n
Zinc binding site 2 out
of 3 in the Structure Cbp TAZ1 Domain
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Structure Cbp TAZ1 Domain within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn441
b:0.0
occ:1.00
|
NE2
|
A:HIS393
|
2.1
|
0.0
|
1.0
|
SG
|
A:CYS403
|
2.3
|
0.0
|
1.0
|
SG
|
A:CYS408
|
2.3
|
0.0
|
1.0
|
SG
|
A:CYS397
|
2.3
|
0.0
|
1.0
|
CD2
|
A:HIS393
|
2.8
|
0.0
|
1.0
|
HD2
|
A:HIS393
|
2.8
|
0.0
|
1.0
|
HB2
|
A:CYS397
|
3.0
|
0.0
|
1.0
|
HB3
|
A:CYS403
|
3.0
|
0.0
|
1.0
|
CB
|
A:CYS403
|
3.1
|
0.0
|
1.0
|
CB
|
A:CYS397
|
3.3
|
0.0
|
1.0
|
CE1
|
A:HIS393
|
3.3
|
0.0
|
1.0
|
HB2
|
A:CYS403
|
3.4
|
0.0
|
1.0
|
CB
|
A:CYS408
|
3.4
|
0.0
|
1.0
|
HB3
|
A:CYS408
|
3.5
|
0.0
|
1.0
|
HB2
|
A:CYS408
|
3.6
|
0.0
|
1.0
|
HE1
|
A:HIS393
|
3.8
|
0.0
|
1.0
|
HB3
|
A:CYS397
|
4.0
|
0.0
|
1.0
|
HB2
|
A:PRO400
|
4.1
|
0.0
|
1.0
|
CG
|
A:HIS393
|
4.1
|
0.0
|
1.0
|
H
|
A:PRO400
|
4.1
|
0.0
|
1.0
|
HA
|
A:MET394
|
4.2
|
0.0
|
1.0
|
HA
|
A:CYS397
|
4.2
|
0.0
|
1.0
|
ND1
|
A:HIS393
|
4.3
|
0.0
|
1.0
|
O
|
A:CYS403
|
4.4
|
0.0
|
1.0
|
CA
|
A:CYS397
|
4.4
|
0.0
|
1.0
|
CA
|
A:CYS403
|
4.5
|
0.0
|
1.0
|
O
|
A:PRO400
|
4.8
|
0.0
|
1.0
|
O
|
A:HIS393
|
4.8
|
0.0
|
1.0
|
CA
|
A:CYS408
|
4.8
|
0.0
|
1.0
|
H
|
A:GLN398
|
4.8
|
0.0
|
1.0
|
N
|
A:PRO400
|
4.9
|
0.0
|
1.0
|
CA
|
A:PRO400
|
4.9
|
0.0
|
1.0
|
C
|
A:CYS403
|
4.9
|
0.0
|
1.0
|
H
|
A:ALA399
|
5.0
|
0.0
|
1.0
|
HA
|
A:CYS403
|
5.0
|
0.0
|
1.0
|
HB
|
A:VAL405
|
5.0
|
0.0
|
1.0
|
|
Zinc binding site 3 out
of 3 in 1u2n
Go back to
Zinc Binding Sites List in 1u2n
Zinc binding site 3 out
of 3 in the Structure Cbp TAZ1 Domain
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Structure Cbp TAZ1 Domain within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn442
b:0.0
occ:1.00
|
NE2
|
A:HIS417
|
2.1
|
0.0
|
1.0
|
SG
|
A:CYS426
|
2.3
|
0.0
|
1.0
|
SG
|
A:CYS429
|
2.3
|
0.0
|
1.0
|
SG
|
A:CYS421
|
2.3
|
0.0
|
1.0
|
HE1
|
A:HIS417
|
2.4
|
0.0
|
1.0
|
CE1
|
A:HIS417
|
2.6
|
0.0
|
1.0
|
HB3
|
A:CYS426
|
2.9
|
0.0
|
1.0
|
CB
|
A:CYS426
|
3.1
|
0.0
|
1.0
|
HB2
|
A:CYS429
|
3.3
|
0.0
|
1.0
|
HB2
|
A:CYS426
|
3.4
|
0.0
|
1.0
|
CD2
|
A:HIS417
|
3.4
|
0.0
|
1.0
|
CB
|
A:CYS429
|
3.4
|
0.0
|
1.0
|
HB3
|
A:CYS421
|
3.7
|
0.0
|
1.0
|
CB
|
A:CYS421
|
3.7
|
0.0
|
1.0
|
HA
|
A:ARG423
|
3.8
|
0.0
|
1.0
|
ND1
|
A:HIS417
|
3.9
|
0.0
|
1.0
|
HA
|
A:CYS421
|
3.9
|
0.0
|
1.0
|
HG2
|
A:ARG423
|
3.9
|
0.0
|
1.0
|
H
|
A:CYS429
|
4.0
|
0.0
|
1.0
|
HD2
|
A:HIS417
|
4.0
|
0.0
|
1.0
|
HB3
|
A:CYS429
|
4.0
|
0.0
|
1.0
|
CG
|
A:HIS417
|
4.3
|
0.0
|
1.0
|
H
|
A:THR422
|
4.4
|
0.0
|
1.0
|
CA
|
A:CYS421
|
4.4
|
0.0
|
1.0
|
H
|
A:ARG423
|
4.5
|
0.0
|
1.0
|
CA
|
A:CYS426
|
4.5
|
0.0
|
1.0
|
HA
|
A:TRP418
|
4.5
|
0.0
|
1.0
|
HB2
|
A:CYS421
|
4.5
|
0.0
|
1.0
|
CA
|
A:CYS429
|
4.6
|
0.0
|
1.0
|
N
|
A:CYS429
|
4.6
|
0.0
|
1.0
|
HD1
|
A:HIS417
|
4.6
|
0.0
|
1.0
|
HA
|
A:CYS429
|
4.7
|
0.0
|
1.0
|
CA
|
A:ARG423
|
4.8
|
0.0
|
1.0
|
H
|
A:VAL428
|
4.8
|
0.0
|
1.0
|
HB
|
A:VAL428
|
4.9
|
0.0
|
1.0
|
HD2
|
A:PRO427
|
4.9
|
0.0
|
1.0
|
CG
|
A:ARG423
|
4.9
|
0.0
|
1.0
|
O
|
A:HIS417
|
5.0
|
0.0
|
1.0
|
N
|
A:ARG423
|
5.0
|
0.0
|
1.0
|
HD1
|
A:TRP418
|
5.0
|
0.0
|
1.0
|
|
Reference:
R.N.De Guzman,
J.M.Wojciak,
M.A.Martinez-Yamout,
H.J.Dyson,
P.E.Wright.
Cbp/P300 TAZ1 Domain Forms A Structured Scaffold For Ligand Binding Biochemistry V. 44 490 2005.
ISSN: ISSN 0006-2960
PubMed: 15641773
DOI: 10.1021/BI048161T
Page generated: Wed Oct 16 19:25:08 2024
|