Zinc in PDB 1tqx: Crystal Structure of PFAL009167 A Putative D-Ribulose 5-Phosphate 3- Epimerase From P.Falciparum

The structure of Crystal Structure of PFAL009167 A Putative D-Ribulose 5-Phosphate 3- Epimerase From P.Falciparum, PDB code: 1tqx was solved by J.Caruthers, J.Bosch, W.G.J.Hol, Structural Genomics Of Pathogenicprotozoa Consortium (Sgpp), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	52.17 / 2.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	79.415, 84.454, 120.717, 90.00, 90.00, 90.00
R / Rfree (%)	21.2 / 23.3

The binding sites of Zinc atom in the Crystal Structure of PFAL009167 A Putative D-Ribulose 5-Phosphate 3- Epimerase From P.Falciparum (pdb code 1tqx). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of PFAL009167 A Putative D-Ribulose 5-Phosphate 3- Epimerase From P.Falciparum, PDB code: 1tqx:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of PFAL009167 A Putative D-Ribulose 5-Phosphate 3- Epimerase From P.Falciparum


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of PFAL009167 A Putative D-Ribulose 5-Phosphate 3- Epimerase From P.Falciparum within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn900 b:23.8 occ:1.00 OD1 A:ASP38 2.1 16.8 1.0 NE2 A:HIS36 2.2 18.4 1.0 OD1 A:ASP179 2.3 26.8 1.0 ND1 A:HIS70 2.3 21.7 1.0 CD2 A:HIS36 3.0 15.6 1.0 CG A:ASP38 3.1 18.3 1.0 CG A:HIS70 3.2 21.7 1.0 CE1 A:HIS70 3.3 21.2 1.0 CE1 A:HIS36 3.4 17.4 1.0 CB A:HIS70 3.4 19.8 1.0 CG A:ASP179 3.4 27.8 1.0 OD2 A:ASP38 3.4 22.5 1.0 CE A:MET72 3.9 29.5 1.0 OD2 A:ASP179 4.0 26.7 1.0 CG A:HIS36 4.2 17.2 1.0 CD1 A:LEU143 4.3 22.5 1.0 ND1 A:HIS36 4.4 18.0 1.0 CD2 A:HIS70 4.4 21.5 1.0 NE2 A:HIS70 4.4 23.7 1.0 CB A:ASP38 4.5 17.8 1.0 CB A:ASP179 4.6 23.6 1.0 CG1 A:VAL199 4.8 18.6 1.0 CA A:HIS70 4.9 18.5 1.0 CA A:ASP38 4.9 19.6 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of PFAL009167 A Putative D-Ribulose 5-Phosphate 3- Epimerase From P.Falciparum


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of PFAL009167 A Putative D-Ribulose 5-Phosphate 3- Epimerase From P.Falciparum within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn902 b:28.8 occ:1.00 OD1 B:ASP38 2.2 22.5 1.0 OD1 B:ASP179 2.2 29.9 1.0 ND1 B:HIS70 2.3 23.8 1.0 NE2 B:HIS36 2.5 24.7 1.0 CD2 B:HIS36 3.1 22.6 1.0 CG B:ASP38 3.1 22.4 1.0 CG B:HIS70 3.3 25.6 1.0 CE1 B:HIS70 3.3 23.8 1.0 OD2 B:ASP38 3.3 25.3 1.0 CG B:ASP179 3.4 28.0 1.0 CB B:HIS70 3.5 21.4 1.0 CE1 B:HIS36 3.7 25.6 1.0 CE B:MET72 3.8 34.4 1.0 OD2 B:ASP179 4.0 30.7 1.0 CD1 B:LEU143 4.3 27.6 1.0 CG B:HIS36 4.4 23.4 1.0 NE2 B:HIS70 4.4 23.5 1.0 CD2 B:HIS70 4.4 23.9 1.0 CB B:ASP38 4.5 21.4 1.0 CB B:ASP179 4.5 26.4 1.0 ND1 B:HIS36 4.6 24.2 1.0 CG1 B:VAL199 4.8 21.7 1.0 CA B:ASP38 4.9 20.2 1.0

J.Caruthers, J.Bosch, F.Buckner, W.Van Voorhis, P.Myler, E.Worthey, C.Mehlin, E.Boni, G.Detitta, J.Luft, A.Lauricella, O.Kalyuzhniy, L.Anderson, F.Zucker, M.Soltis, W.G.Hol. Structure of A Ribulose 5-Phosphate 3-Epimerase From Plasmodium Falciparum. Proteins V. 62 338 2006.
ISSN: ISSN 0887-3585
PubMed: 16304640
DOI: 10.1002/PROT.20764