Atomistry » Zinc » PDB 1tnz-1u1j » 1tqu
Atomistry »
  Zinc »
    PDB 1tnz-1u1j »
      1tqu »

Zinc in PDB 1tqu: Golgi Alpha-Mannosidase II in Complex with the Salacinol Analog Ghavamiol

Enzymatic activity of Golgi Alpha-Mannosidase II in Complex with the Salacinol Analog Ghavamiol

All present enzymatic activity of Golgi Alpha-Mannosidase II in Complex with the Salacinol Analog Ghavamiol:
3.2.1.114;

Protein crystallography data

The structure of Golgi Alpha-Mannosidase II in Complex with the Salacinol Analog Ghavamiol, PDB code: 1tqu was solved by D.A.Kuntz, A.Ghavami, B.D.Johnston, B.M.Pinto, D.R.Rose, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.46 / 2.03
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 68.298, 108.957, 137.723, 90.00, 90.00, 90.00
R / Rfree (%) 13.2 / 18.2

Zinc Binding Sites:

The binding sites of Zinc atom in the Golgi Alpha-Mannosidase II in Complex with the Salacinol Analog Ghavamiol (pdb code 1tqu). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Golgi Alpha-Mannosidase II in Complex with the Salacinol Analog Ghavamiol, PDB code: 1tqu:

Zinc binding site 1 out of 1 in 1tqu

Go back to Zinc Binding Sites List in 1tqu
Zinc binding site 1 out of 1 in the Golgi Alpha-Mannosidase II in Complex with the Salacinol Analog Ghavamiol


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Golgi Alpha-Mannosidase II in Complex with the Salacinol Analog Ghavamiol within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1400

b:11.7
occ:1.00
NE2 A:HIS90 2.1 7.4 1.0
OD1 A:ASP92 2.1 12.8 1.0
NE2 A:HIS471 2.1 8.7 1.0
O2 A:GHA1300 2.1 14.1 1.0
OD1 A:ASP204 2.2 7.7 1.0
CG A:ASP92 2.9 10.1 1.0
OD2 A:ASP92 3.0 7.5 1.0
CD2 A:HIS90 3.0 7.7 1.0
CD2 A:HIS471 3.0 7.5 1.0
CE1 A:HIS90 3.0 8.9 1.0
CG A:ASP204 3.1 10.3 1.0
CE1 A:HIS471 3.1 9.6 1.0
C2 A:GHA1300 3.1 15.2 1.0
C3 A:GHA1300 3.4 17.6 1.0
CB A:ASP204 3.4 5.8 1.0
OD2 A:ASP472 4.0 7.1 1.0
C1 A:GHA1300 4.1 15.2 1.0
N4 A:GHA1300 4.1 15.6 1.0
ND1 A:HIS90 4.1 8.1 1.0
CG A:HIS90 4.2 6.6 1.0
CG A:HIS471 4.2 7.9 1.0
ND1 A:HIS471 4.2 8.3 1.0
O A:HOH2449 4.2 8.9 1.0
CE1 A:HIS470 4.2 9.2 1.0
OD2 A:ASP204 4.2 9.8 1.0
CB A:ASP92 4.2 5.5 1.0
C5 A:GHA1300 4.8 15.7 1.0
OH A:TYR269 4.8 11.2 1.0
CA A:ASP204 4.8 7.7 1.0
CA A:ASP92 4.9 8.7 1.0
NE2 A:HIS470 4.9 8.0 1.0
CG A:ASP472 5.0 7.9 1.0

Reference:

D.A.Kuntz, A.Ghavami, B.D.Johnston, B.M.Pinto, D.R.Rose. Crystallographic Analysis of the Interactions of Drosophila Melanogaster Golgi Alpha-Mannosidase II with the Naturally Occurring Glycomimetic Salacinol and Its Analogues Tetrahedron Asymmetry V. 16 25 2005.
ISSN: ISSN 0957-4166
Page generated: Wed Oct 16 19:16:23 2024

Last articles

Zn in 9FD2
Zn in 9GUW
Zn in 9GUX
Zn in 9F7C
Zn in 9GUR
Zn in 9F7A
Zn in 9DDE
Zn in 9DBY
Zn in 9EBZ
Zn in 9DGG
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy