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Atomistry » Zinc » PDB 1sxa-1tbf » 1tbf » |
Zinc in PDB 1tbf: Catalytic Domain of Human Phosphodiesterase 5A in Complex with SildenafilEnzymatic activity of Catalytic Domain of Human Phosphodiesterase 5A in Complex with Sildenafil
All present enzymatic activity of Catalytic Domain of Human Phosphodiesterase 5A in Complex with Sildenafil:
3.1.4.17; Protein crystallography data
The structure of Catalytic Domain of Human Phosphodiesterase 5A in Complex with Sildenafil, PDB code: 1tbf
was solved by
K.Y.J.Zhang,
G.L.Card,
Y.Suzuki,
D.R.Artis,
D.Fong,
S.Gillette,
D.Hsieh,
J.Neiman,
B.L.West,
C.Zhang,
M.V.Milburn,
S.-H.Kim,
J.Schlessinger,
G.Bollag,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1tbf:
The structure of Catalytic Domain of Human Phosphodiesterase 5A in Complex with Sildenafil also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Catalytic Domain of Human Phosphodiesterase 5A in Complex with Sildenafil
(pdb code 1tbf). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Catalytic Domain of Human Phosphodiesterase 5A in Complex with Sildenafil, PDB code: 1tbf: Zinc binding site 1 out of 1 in 1tbfGo back to Zinc Binding Sites List in 1tbf
Zinc binding site 1 out
of 1 in the Catalytic Domain of Human Phosphodiesterase 5A in Complex with Sildenafil
Mono view Stereo pair view
Reference:
K.Y.J.Zhang,
G.L.Card,
Y.Suzuki,
D.R.Artis,
D.Fong,
S.Gillette,
D.Hsieh,
J.Neiman,
B.L.West,
C.Zhang,
M.V.Milburn,
S.-H.Kim,
J.Schlessinger,
G.Bollag.
A Glutamine Switch Mechanism For Nucleotide Selectivity By Phosphodiesterases Mol.Cell V. 15 279 2004.
Page generated: Mon Jan 25 16:14:03 2021
ISSN: ISSN 1097-2765 PubMed: 15260978 DOI: 10.1016/J.MOLCEL.2004.07.005 |
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