Atomistry » Zinc » PDB 1sxa-1tbf » 1t67
Atomistry »
  Zinc »
    PDB 1sxa-1tbf »
      1t67 »

Zinc in PDB 1t67: Crystal Structure of Human HDAC8 Complexed with Ms-344

Protein crystallography data

The structure of Crystal Structure of Human HDAC8 Complexed with Ms-344, PDB code: 1t67 was solved by J.R.Somoza, R.J.Skene, B.A.Katz, C.Mol, J.D.Ho, A.J.Jennings, C.Luong, A.Arvai, J.J.Buggy, E.Chi, J.Tang, B.-C.Sang, E.Verner, R.Wynands, E.M.Leahy, D.R.Dougan, G.Snell, M.Navre, M.W.Knuth, R.V.Swanson, D.E.Mcree, L.W.Tari, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 69.01 / 2.31
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 80.644, 80.644, 105.523, 90.00, 90.00, 120.00
R / Rfree (%) 21.2 / 27.4

Other elements in 1t67:

The structure of Crystal Structure of Human HDAC8 Complexed with Ms-344 also contains other interesting chemical elements:

Sodium (Na) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Human HDAC8 Complexed with Ms-344 (pdb code 1t67). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human HDAC8 Complexed with Ms-344, PDB code: 1t67:

Zinc binding site 1 out of 1 in 1t67

Go back to Zinc Binding Sites List in 1t67
Zinc binding site 1 out of 1 in the Crystal Structure of Human HDAC8 Complexed with Ms-344


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human HDAC8 Complexed with Ms-344 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn378

b:46.9
occ:1.00
OD2 A:ASP178 2.0 33.3 1.0
O4 A:B3N381 2.0 52.7 1.0
OD2 A:ASP267 2.0 41.5 1.0
O2 A:B3N381 2.0 53.8 1.0
ND1 A:HIS180 2.1 33.5 1.0
C1 A:B3N381 2.6 55.2 1.0
N3 A:B3N381 2.6 54.9 1.0
CG A:ASP178 2.9 34.1 1.0
CE1 A:HIS180 2.9 33.8 1.0
CG A:ASP267 3.1 39.2 1.0
OD1 A:ASP178 3.1 30.7 1.0
CG A:HIS180 3.2 33.5 1.0
OD1 A:ASP267 3.5 38.8 1.0
CB A:HIS180 3.6 33.3 1.0
N A:HIS180 3.7 34.0 1.0
CA A:GLY304 3.9 35.5 1.0
NE2 A:HIS180 4.1 35.8 1.0
C5 A:B3N381 4.1 55.6 1.0
CD2 A:HIS180 4.2 36.7 1.0
OH A:TYR306 4.2 33.2 1.0
N A:LEU179 4.2 34.5 1.0
N A:GLY304 4.2 35.6 1.0
CA A:HIS180 4.3 33.4 1.0
CB A:ASP178 4.3 34.0 1.0
CB A:ASP267 4.4 37.0 1.0
NE2 A:HIS142 4.5 31.1 1.0
CB A:LEU179 4.5 34.0 1.0
C6 A:B3N381 4.5 55.6 1.0
CE1 A:TYR306 4.6 33.4 1.0
C A:LEU179 4.6 33.9 1.0
CA A:LEU179 4.6 34.2 1.0
CZ A:TYR306 4.9 35.2 1.0
CE1 A:HIS142 4.9 30.7 1.0
C A:ASP178 5.0 34.3 1.0

Reference:

J.R.Somoza, R.J.Skene, B.A.Katz, C.Mol, J.D.Ho, A.J.Jennings, C.Luong, A.Arvai, J.J.Buggy, E.Chi, J.Tang, B.-C.Sang, E.Verner, R.Wynands, E.M.Leahy, D.R.Dougan, G.Snell, M.Navre, M.W.Knuth, R.V.Swanson, D.E.Mcree, L.W.Tari. Structural Snapshots of Human HDAC8 Provide Insights Into the Class I Histone Deacetylases Structure V. 12 1325 2004.
ISSN: ISSN 0969-2126
PubMed: 15242608
DOI: 10.1016/J.STR.2004.04.012
Page generated: Mon Jan 25 16:13:38 2021

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy