Zinc in PDB 1srp: Structural Analysis of Serratia Protease

All present enzymatic activity of Structural Analysis of Serratia Protease:
3.4.24.40;

The structure of Structural Analysis of Serratia Protease, PDB code: 1srp was solved by K.Hamada, H.Hiramatsu, Y.Katsuya, Y.Hata, Y.Katsube, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	8.00 / 2.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	109.140, 150.890, 42.640, 90.00, 90.00, 90.00
R / Rfree (%)	n/a / n/a

The structure of Structural Analysis of Serratia Protease also contains other interesting chemical elements:

Calcium

(Ca)

7 atoms

The binding sites of Zinc atom in the Structural Analysis of Serratia Protease (pdb code 1srp). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structural Analysis of Serratia Protease, PDB code: 1srp:

Zinc binding site 1 out of 1 in the Structural Analysis of Serratia Protease


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structural Analysis of Serratia Protease within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn920 b:16.5 occ:1.00 NE2 A:HIS186 1.9 14.5 1.0 NE2 A:HIS176 2.0 11.8 1.0 O A:HOH557 2.1 21.3 1.0 NE2 A:HIS180 2.1 12.1 1.0 CE1 A:HIS176 2.9 12.5 1.0 CE1 A:HIS186 2.9 15.5 1.0 CD2 A:HIS186 3.0 15.6 1.0 CE1 A:HIS180 3.0 12.8 1.0 CD2 A:HIS180 3.1 12.8 1.0 OH A:TYR216 3.1 27.6 1.0 CD2 A:HIS176 3.1 12.6 1.0 CZ A:TYR216 3.9 26.5 1.0 O A:HOH693 3.9 27.4 1.0 ND1 A:HIS186 4.0 15.5 1.0 ND1 A:HIS176 4.1 12.7 1.0 CG A:HIS186 4.1 15.9 1.0 OE2 A:GLU177 4.1 12.0 1.0 CE2 A:TYR216 4.1 25.7 1.0 ND1 A:HIS180 4.2 13.3 1.0 CG A:HIS176 4.2 12.1 1.0 CG A:HIS180 4.2 12.9 1.0 OE1 A:GLU177 4.4 12.6 1.0 CD A:GLU177 4.7 12.4 1.0 CE A:MET214 4.7 14.0 1.0 O A:HOH705 4.8 37.9 1.0 CE1 A:TYR216 5.0 26.6 1.0

K.Hamada, Y.Hata, Y.Katsuya, H.Hiramatsu, T.Fujiwara, Y.Katsube. Crystal Structure of Serratia Protease, A Zinc-Dependent Proteinase From Serratia Sp. E-15, Containing A Beta-Sheet Coil Motif at 2.0 A Resolution. J.Biochem.(Tokyo) V. 119 844 1996.
ISSN: ISSN 0021-924X
PubMed: 8797082