Zinc in PDB 2alu: Detection of New Binding Site in the C-Terminal Lobe of Lactoferrin:Crystal Structure of the Complex Formed Between Bovine Lactoferrin and A Tetrasaccharide at 2.1A Resolution

The structure of Detection of New Binding Site in the C-Terminal Lobe of Lactoferrin:Crystal Structure of the Complex Formed Between Bovine Lactoferrin and A Tetrasaccharide at 2.1A Resolution, PDB code: 2alu was solved by N.Singh, T.Jabeen, S.Sharma, A.Bhushan, T.P.Singh, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	63.25 / 2.09
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	63.508, 50.518, 66.114, 90.00, 107.76, 90.00
R / Rfree (%)	19.8 / 21.2

The structure of Detection of New Binding Site in the C-Terminal Lobe of Lactoferrin:Crystal Structure of the Complex Formed Between Bovine Lactoferrin and A Tetrasaccharide at 2.1A Resolution also contains other interesting chemical elements:

Iron

(Fe)

1 atom

The binding sites of Zinc atom in the Detection of New Binding Site in the C-Terminal Lobe of Lactoferrin:Crystal Structure of the Complex Formed Between Bovine Lactoferrin and A Tetrasaccharide at 2.1A Resolution (pdb code 2alu). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Detection of New Binding Site in the C-Terminal Lobe of Lactoferrin:Crystal Structure of the Complex Formed Between Bovine Lactoferrin and A Tetrasaccharide at 2.1A Resolution, PDB code: 2alu:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Detection of New Binding Site in the C-Terminal Lobe of Lactoferrin:Crystal Structure of the Complex Formed Between Bovine Lactoferrin and A Tetrasaccharide at 2.1A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Detection of New Binding Site in the C-Terminal Lobe of Lactoferrin:Crystal Structure of the Complex Formed Between Bovine Lactoferrin and A Tetrasaccharide at 2.1A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn302 b:27.9 occ:1.00 OE2 A:GLU659 2.0 23.1 1.0 O A:HOH885 2.1 32.9 1.0 OE1 A:GLU659 2.4 13.9 1.0 CD A:GLU659 2.5 19.2 1.0 O A:GLY653 4.0 34.3 1.0 CG A:GLU659 4.0 19.0 1.0 O A:HOH950 4.3 37.3 1.0 O A:ARG654 4.3 28.3 1.0 CA A:PRO655 4.6 26.8 1.0 CB A:GLU659 4.9 19.7 1.0 N A:THR656 4.9 24.2 1.0 CG2 A:THR656 5.0 21.2 1.0 C A:ARG654 5.0 29.3 1.0

Zinc binding site 2 out of 2 in the Detection of New Binding Site in the C-Terminal Lobe of Lactoferrin:Crystal Structure of the Complex Formed Between Bovine Lactoferrin and A Tetrasaccharide at 2.1A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Detection of New Binding Site in the C-Terminal Lobe of Lactoferrin:Crystal Structure of the Complex Formed Between Bovine Lactoferrin and A Tetrasaccharide at 2.1A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn303 b:31.9 occ:1.00 O A:HOH862 2.0 32.2 1.0 NE2 A:HIS588 2.1 25.5 1.0 O A:HOH897 2.1 30.6 1.0 O A:HOH896 2.2 55.5 1.0 CE1 A:HIS588 3.0 24.5 1.0 CD2 A:HIS588 3.1 23.6 1.0 O A:HOH884 4.1 41.1 1.0 ND1 A:HIS588 4.2 20.7 1.0 CG1 A:VAL591 4.2 25.7 1.0 CG A:HIS588 4.2 22.5 1.0 O A:HOH974 4.6 49.1 1.0 O A:HOH742 4.8 28.5 1.0

N.Singh, T.Jabeen, S.Sharma, A.Bhushan, T.P.Singh. Detection of New Binding Site in the C-Terminal Lobe of Lactoferrin:Crystal Structure of the Complex Formed Between Bovine Lactoferrin and A Tetrasaccharide at 2.1A Resolution To Be Published.