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Zinc in PDB 1pqv: Rna Polymerase II-Tfiis Complex

Enzymatic activity of Rna Polymerase II-Tfiis Complex

All present enzymatic activity of Rna Polymerase II-Tfiis Complex:
2.7.7.6;

Protein crystallography data

The structure of Rna Polymerase II-Tfiis Complex, PDB code: 1pqv was solved by H.Kettenberger, K.-J.Armache, P.Cramer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 3.80
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 218.900, 395.300, 281.000, 90.00, 90.00, 90.00
R / Rfree (%) n/a / n/a

Other elements in 1pqv:

The structure of Rna Polymerase II-Tfiis Complex also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Rna Polymerase II-Tfiis Complex (pdb code 1pqv). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 9 binding sites of Zinc where determined in the Rna Polymerase II-Tfiis Complex, PDB code: 1pqv:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9;

Zinc binding site 1 out of 9 in 1pqv

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Zinc binding site 1 out of 9 in the Rna Polymerase II-Tfiis Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Rna Polymerase II-Tfiis Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1735

b:30.0
occ:1.00
 CA A:CYS110 3.7 30.0 1.0

Zinc binding site 2 out of 9 in 1pqv

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Zinc binding site 2 out of 9 in the Rna Polymerase II-Tfiis Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Rna Polymerase II-Tfiis Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1736

b:30.0
occ:1.00
 CA A:CYS67 3.5 30.0 1.0
CA A:CYS77 4.6 30.0 1.0
CA A:CYS70 4.7 30.0 1.0
CA A:GLY59 4.8 30.0 1.0
CA A:GLN68 5.0 30.0 1.0

Zinc binding site 3 out of 9 in 1pqv

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Zinc binding site 3 out of 9 in the Rna Polymerase II-Tfiis Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Rna Polymerase II-Tfiis Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn1300

b:30.0
occ:1.00
 CA B:CYS1185 4.6 30.0 1.0
CA B:CYS1182 4.6 30.0 1.0
CA B:CYS1163 4.7 30.0 1.0
CA B:CYS1166 4.9 30.0 1.0

Zinc binding site 4 out of 9 in 1pqv

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Zinc binding site 4 out of 9 in the Rna Polymerase II-Tfiis Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Rna Polymerase II-Tfiis Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn319

b:30.0
occ:1.00
 CA C:CYS92 4.1 30.0 1.0
CA C:CYS86 4.2 30.0 1.0
CA C:HIS91 4.2 30.0 1.0
CA C:CYS88 4.3 30.0 1.0
CA C:CYS95 4.4 30.0 1.0

Zinc binding site 5 out of 9 in 1pqv

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Zinc binding site 5 out of 9 in the Rna Polymerase II-Tfiis Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Rna Polymerase II-Tfiis Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
I:Zn200

b:30.0
occ:1.00
 CA I:CYS10 4.3 30.0 1.0
CA I:CYS29 4.4 30.0 1.0
CA I:CYS7 4.6 30.0 1.0
CA I:CYS32 4.7 30.0 1.0

Zinc binding site 6 out of 9 in 1pqv

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Zinc binding site 6 out of 9 in the Rna Polymerase II-Tfiis Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Rna Polymerase II-Tfiis Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
I:Zn201

b:30.0
occ:1.00
 CA I:CYS75 4.0 30.0 1.0
CA I:CYS103 4.0 30.0 1.0
CA I:CYS106 4.3 30.0 1.0
CA I:CYS78 4.4 30.0 1.0
CA I:HIS108 4.8 30.0 1.0

Zinc binding site 7 out of 9 in 1pqv

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Zinc binding site 7 out of 9 in the Rna Polymerase II-Tfiis Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of Rna Polymerase II-Tfiis Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
J:Zn100

b:30.0
occ:1.00
 CA J:CYS46 3.3 30.0 1.0
CA J:CYS45 3.9 30.0 1.0
CA J:CYS10 4.1 30.0 1.0
CA J:CYS7 5.0 30.0 1.0

Zinc binding site 8 out of 9 in 1pqv

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Zinc binding site 8 out of 9 in the Rna Polymerase II-Tfiis Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 8 of Rna Polymerase II-Tfiis Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
L:Zn100

b:30.0
occ:1.00
 CA L:CYS34 4.3 30.0 1.0
CA L:CYS51 4.5 30.0 1.0
CA L:CYS48 4.8 30.0 1.0
CA L:CYS31 4.9 30.0 1.0

Zinc binding site 9 out of 9 in 1pqv

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Zinc binding site 9 out of 9 in the Rna Polymerase II-Tfiis Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 9 of Rna Polymerase II-Tfiis Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
S:Zn400

b:30.0
occ:1.00
 CA S:CYS274 3.1 30.0 1.0
CA S:LYS273 3.8 30.0 1.0
CA S:CYS271 4.9 30.0 1.0

Reference:

H.Kettenberger, K.-J.Armache, P.Cramer. Architecture of the Rna Polymerase II-Tfiis Complex and Implications For Mrna Cleavage Cell(Cambridge,Mass.) V. 114 347 2003.
ISSN: ISSN 0092-8674
PubMed: 12914699
DOI: 10.1016/S0092-8674(03)00598-1
Page generated: Wed Oct 16 17:53:18 2024

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