Atomistry » Zinc » PDB 1peg-1pv9 » 1pjp
Atomistry »
  Zinc »
    PDB 1peg-1pv9 »
      1pjp »

Zinc in PDB 1pjp: The 2.2 A Crystal Structure of Human Chymase in Complex with Succinyl- Ala-Ala-Pro-Phe-Chloromethylketone

Enzymatic activity of The 2.2 A Crystal Structure of Human Chymase in Complex with Succinyl- Ala-Ala-Pro-Phe-Chloromethylketone

All present enzymatic activity of The 2.2 A Crystal Structure of Human Chymase in Complex with Succinyl- Ala-Ala-Pro-Phe-Chloromethylketone:
3.4.21.39;

Protein crystallography data

The structure of The 2.2 A Crystal Structure of Human Chymase in Complex with Succinyl- Ala-Ala-Pro-Phe-Chloromethylketone, PDB code: 1pjp was solved by P.J.B.Pereira, Z.M.Wang, H.Rubin, R.Huber, W.Bode, N.M.Schechter, S.Strobl, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 8.00 / 2.20
Space group P 43
Cell size a, b, c (Å), α, β, γ (°) 74.370, 74.370, 50.090, 90.00, 90.00, 90.00
R / Rfree (%) 18.4 / 23.7

Zinc Binding Sites:

The binding sites of Zinc atom in the The 2.2 A Crystal Structure of Human Chymase in Complex with Succinyl- Ala-Ala-Pro-Phe-Chloromethylketone (pdb code 1pjp). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the The 2.2 A Crystal Structure of Human Chymase in Complex with Succinyl- Ala-Ala-Pro-Phe-Chloromethylketone, PDB code: 1pjp:

Zinc binding site 1 out of 1 in 1pjp

Go back to Zinc Binding Sites List in 1pjp
Zinc binding site 1 out of 1 in the The 2.2 A Crystal Structure of Human Chymase in Complex with Succinyl- Ala-Ala-Pro-Phe-Chloromethylketone


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The 2.2 A Crystal Structure of Human Chymase in Complex with Succinyl- Ala-Ala-Pro-Phe-Chloromethylketone within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1000

b:22.8
occ:1.00
 OE2 A:GLU84 1.9 22.6 1.0
NZ A:LYS109 2.4 24.6 1.0
CD A:GLU84 2.8 20.4 1.0
OE1 A:GLU84 3.0 22.2 1.0
CE A:LYS109 3.1 24.9 1.0
CD A:LYS109 3.5 24.6 1.0
O A:HOH1015 4.1 20.9 1.0
CG A:GLU84 4.2 18.8 1.0
CG2 A:ILE86 4.3 15.7 1.0
O A:HOH1140 4.5 60.3 1.0
CG A:LYS109 4.6 23.8 1.0

Reference:

P.J.Pereira, Z.M.Wang, H.Rubin, R.Huber, W.Bode, N.M.Schechter, S.Strobl. The 2.2 A Crystal Structure of Human Chymase in Complex with Succinyl-Ala-Ala-Pro-Phe-Chloromethylketone: Structural Explanation For Its Dipeptidyl Carboxypeptidase Specificity. J.Mol.Biol. V. 286 163 1999.
ISSN: ISSN 0022-2836
PubMed: 9931257
DOI: 10.1006/JMBI.1998.2462
Page generated: Wed Oct 16 17:50:49 2024

Last articles

Zn in 9J0N
Zn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy