Zinc in PDB 1piw: Apo and Holo Structures of An Nadp(H)-Dependent Cinnamyl Alcohol Dehydrogenase From Saccharomyces Cerevisiae

The structure of Apo and Holo Structures of An Nadp(H)-Dependent Cinnamyl Alcohol Dehydrogenase From Saccharomyces Cerevisiae, PDB code: 1piw was solved by E.Valencia, C.Larroy, W.F.Ochoa, X.Pares, I.Fita, J.A.Biosca, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 3.00
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	234.980, 100.350, 52.490, 90.00, 92.18, 90.00
R / Rfree (%)	21.8 / 27.1

The binding sites of Zinc atom in the Apo and Holo Structures of An Nadp(H)-Dependent Cinnamyl Alcohol Dehydrogenase From Saccharomyces Cerevisiae (pdb code 1piw). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Apo and Holo Structures of An Nadp(H)-Dependent Cinnamyl Alcohol Dehydrogenase From Saccharomyces Cerevisiae, PDB code: 1piw:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Apo and Holo Structures of An Nadp(H)-Dependent Cinnamyl Alcohol Dehydrogenase From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Apo and Holo Structures of An Nadp(H)-Dependent Cinnamyl Alcohol Dehydrogenase From Saccharomyces Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1501 b:40.3 occ:1.00 SG A:CYS103 2.3 48.7 1.0 SG A:CYS100 2.3 38.1 1.0 SG A:CYS106 2.4 40.9 1.0 SG A:CYS114 2.4 36.4 1.0 CB A:CYS114 3.2 38.0 1.0 CB A:CYS103 3.4 50.8 1.0 CB A:CYS100 3.4 38.6 1.0 CB A:CYS106 3.5 40.5 1.0 N A:CYS103 3.8 51.8 1.0 N A:CYS100 3.8 40.2 1.0 N A:LEU101 3.9 43.4 1.0 OG A:SER99 3.9 42.6 1.0 CA A:CYS100 4.0 40.6 1.0 CA A:CYS114 4.1 38.4 1.0 CA A:CYS103 4.2 51.4 1.0 N A:CYS106 4.2 39.3 1.0 C A:CYS100 4.2 41.3 1.0 N A:GLU102 4.3 50.4 1.0 CA A:CYS106 4.4 40.5 1.0 N A:THR115 4.7 42.1 1.0 O A:CYS103 4.7 51.1 1.0 CA A:LEU101 4.7 44.4 1.0 C A:CYS103 4.7 51.7 1.0 C A:SER99 4.8 39.5 1.0 C A:CYS114 4.8 39.3 1.0 C A:GLU102 4.9 52.5 1.0

Zinc binding site 2 out of 4 in the Apo and Holo Structures of An Nadp(H)-Dependent Cinnamyl Alcohol Dehydrogenase From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Apo and Holo Structures of An Nadp(H)-Dependent Cinnamyl Alcohol Dehydrogenase From Saccharomyces Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1502 b:32.3 occ:1.00 NE2 A:HIS68 2.3 35.2 1.0 SG A:CYS163 2.4 34.2 1.0 SG A:CYS46 2.4 24.4 1.0 CE1 A:HIS68 2.8 36.4 1.0 C5N A:NAP4292 2.9 73.8 0.0 CD2 A:HIS68 3.4 38.6 1.0 OG A:SER48 3.5 39.2 1.0 C4N A:NAP4292 3.7 74.1 0.0 CB A:CYS46 3.7 28.9 1.0 C6N A:NAP4292 3.7 73.1 0.0 CB A:CYS163 3.7 34.1 1.0 CB A:SER48 3.9 36.2 1.0 ND1 A:HIS68 4.0 37.0 1.0 CG A:HIS68 4.3 38.1 1.0 OE2 A:GLU69 4.4 30.9 1.0 N A:GLY164 4.7 33.1 1.0 CB A:ALA95 4.7 35.0 1.0 C A:CYS163 4.8 34.1 1.0 N A:SER48 4.9 33.9 1.0 CA A:CYS163 4.9 34.4 1.0 N1N A:NAP4292 4.9 72.2 0.0 C3N A:NAP4292 4.9 74.3 0.0

Zinc binding site 3 out of 4 in the Apo and Holo Structures of An Nadp(H)-Dependent Cinnamyl Alcohol Dehydrogenase From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Apo and Holo Structures of An Nadp(H)-Dependent Cinnamyl Alcohol Dehydrogenase From Saccharomyces Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1501 b:52.4 occ:1.00 SG B:CYS114 2.4 55.8 1.0 SG B:CYS103 2.4 58.2 1.0 SG B:CYS100 2.4 62.4 1.0 SG B:CYS106 2.5 48.7 1.0 CB B:CYS114 3.3 52.4 1.0 CB B:CYS103 3.4 58.3 1.0 CB B:CYS100 3.5 58.7 1.0 OG B:SER99 3.5 54.0 1.0 CB B:CYS106 3.6 50.4 1.0 N B:CYS100 3.8 57.2 1.0 N B:CYS103 3.8 60.8 1.0 N B:LEU101 3.8 59.6 1.0 CA B:CYS100 4.0 58.3 1.0 CA B:CYS103 4.1 59.2 1.0 CA B:CYS114 4.2 53.3 1.0 C B:CYS100 4.2 58.5 1.0 N B:GLU102 4.4 63.5 1.0 N B:CYS106 4.4 51.2 1.0 CA B:CYS106 4.6 51.4 1.0 O B:CYS103 4.6 59.3 1.0 N B:THR115 4.6 53.5 1.0 CA B:LEU101 4.7 61.2 1.0 C B:SER99 4.7 55.8 1.0 C B:CYS103 4.7 58.6 1.0 CB B:SER99 4.8 53.5 1.0 C B:CYS114 4.9 53.3 1.0 C B:GLU102 5.0 63.0 1.0 C B:LEU101 5.0 62.5 1.0

Zinc binding site 4 out of 4 in the Apo and Holo Structures of An Nadp(H)-Dependent Cinnamyl Alcohol Dehydrogenase From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Apo and Holo Structures of An Nadp(H)-Dependent Cinnamyl Alcohol Dehydrogenase From Saccharomyces Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1502 b:65.3 occ:1.00 NE2 B:HIS68 2.1 62.4 1.0 SG B:CYS163 2.3 52.8 1.0 SG B:CYS46 2.5 63.8 1.0 CE1 B:HIS68 2.8 62.8 1.0 OG B:SER48 2.9 62.7 1.0 CD2 B:HIS68 3.3 63.4 1.0 C5N B:NAP4293 3.3 50.0 0.2 CB B:CYS46 3.4 64.8 1.0 CB B:CYS163 3.6 53.9 1.0 ND1 B:HIS68 4.0 63.7 1.0 C6N B:NAP4293 4.0 50.0 0.2 C4N B:NAP4293 4.2 50.0 0.2 CB B:SER48 4.2 62.2 1.0 CG B:HIS68 4.2 63.3 1.0 CB B:ALA95 4.5 52.8 1.0 N B:GLY164 4.8 53.3 1.0 CA B:CYS46 4.8 65.2 1.0 CA B:CYS163 4.9 54.2 1.0

E.Valencia, C.Larroy, W.F.Ochoa, X.Pares, I.Fita, J.A.Biosca. Apo and Holo Structures of An Nadp(H)-Dependent Cinnamyl Alcohol Dehydrogenase From Saccharomyces Cerevisiae J.Mol.Biol. V. 341 1049 2004.
ISSN: ISSN 0022-2836
PubMed: 15289102
DOI: 10.1016/J.JMB.2004.06.037