Zinc in PDB 1occ: Structure of Bovine Heart Cytochrome C Oxidase at the Fully Oxidized State

All present enzymatic activity of Structure of Bovine Heart Cytochrome C Oxidase at the Fully Oxidized State:
1.9.3.1;

The structure of Structure of Bovine Heart Cytochrome C Oxidase at the Fully Oxidized State, PDB code: 1occ was solved by T.Tsukihara, H.Aoyama, E.Yamashita, T.Tomizaki, H.Yamaguchi, K.Shinzawa-Itoh, R.Nakashima, R.Yaono, S.Yoshikawa, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 2.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	189.100, 210.500, 178.600, 90.00, 90.00, 90.00
R / Rfree (%)	20.1 / 25.2

The structure of Structure of Bovine Heart Cytochrome C Oxidase at the Fully Oxidized State also contains other interesting chemical elements:

Magnesium	(Mg)	2 atoms
Iron	(Fe)	4 atoms
Copper	(Cu)	6 atoms

The binding sites of Zinc atom in the Structure of Bovine Heart Cytochrome C Oxidase at the Fully Oxidized State (pdb code 1occ). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of Bovine Heart Cytochrome C Oxidase at the Fully Oxidized State, PDB code: 1occ:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of Bovine Heart Cytochrome C Oxidase at the Fully Oxidized State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Bovine Heart Cytochrome C Oxidase at the Fully Oxidized State within 5.0Å range: probe atom residue distance (Å) B Occ F:Zn99 b:19.2 occ:1.00 SG F:CYS60 2.4 16.4 1.0 SG F:CYS82 2.5 17.6 1.0 SG F:CYS85 2.5 21.5 1.0 SG F:CYS62 2.5 23.4 1.0 CB F:CYS82 3.0 18.1 1.0 CB F:CYS60 3.1 17.9 1.0 CB F:CYS62 3.7 19.6 1.0 OG F:SER84 3.7 50.5 1.0 CA F:CYS62 3.8 19.5 1.0 CB F:CYS85 3.9 11.6 1.0 N F:CYS62 4.0 16.2 1.0 N F:CYS85 4.2 26.3 1.0 O F:CYS60 4.2 24.4 1.0 C F:CYS60 4.3 17.1 1.0 CA F:CYS60 4.3 14.0 1.0 OG1 F:THR87 4.5 19.6 1.0 CA F:CYS82 4.5 13.5 1.0 CA F:CYS85 4.5 23.6 1.0 CB F:THR87 4.8 15.2 1.0 C F:ILE61 4.9 19.0 1.0 C F:SER84 4.9 27.1 1.0 C F:CYS82 5.0 13.3 1.0

Zinc binding site 2 out of 2 in the Structure of Bovine Heart Cytochrome C Oxidase at the Fully Oxidized State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Bovine Heart Cytochrome C Oxidase at the Fully Oxidized State within 5.0Å range: probe atom residue distance (Å) B Occ S:Zn99 b:19.2 occ:1.00 SG S:CYS60 2.4 16.4 1.0 SG S:CYS82 2.5 17.6 1.0 SG S:CYS85 2.5 21.5 1.0 SG S:CYS62 2.5 23.4 1.0 CB S:CYS82 3.0 18.1 1.0 CB S:CYS60 3.1 17.9 1.0 CB S:CYS62 3.7 19.6 1.0 OG S:SER84 3.7 50.5 1.0 CA S:CYS62 3.8 19.5 1.0 CB S:CYS85 3.9 11.6 1.0 N S:CYS62 4.0 16.2 1.0 N S:CYS85 4.2 26.3 1.0 O S:CYS60 4.2 24.4 1.0 C S:CYS60 4.3 17.1 1.0 CA S:CYS60 4.3 14.0 1.0 OG1 S:THR87 4.5 19.6 1.0 CA S:CYS82 4.5 13.5 1.0 CA S:CYS85 4.5 23.6 1.0 CB S:THR87 4.8 15.2 1.0 C S:ILE61 4.9 19.0 1.0 C S:SER84 4.9 27.1 1.0 C S:CYS82 5.0 13.3 1.0

T.Tsukihara, H.Aoyama, E.Yamashita, T.Tomizaki, H.Yamaguchi, K.Shinzawa-Itoh, R.Nakashima, R.Yaono, S.Yoshikawa. The Whole Structure of the 13-Subunit Oxidized Cytochrome C Oxidase at 2.8 A. Science V. 272 1136 1996.
ISSN: ISSN 0036-8075
PubMed: 8638158