Zinc in PDB 1nkx: Crystal Structure of A Proteolytically Generated Functional Monoferric C-Lobe of Bovine Lactoferrin at 1.9A Resolution

The structure of Crystal Structure of A Proteolytically Generated Functional Monoferric C-Lobe of Bovine Lactoferrin at 1.9A Resolution, PDB code: 1nkx was solved by S.Sharma, J.Jasti, J.Kumar, A.K.Mohanty, T.P.Singh, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.90
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	63.359, 50.471, 65.934, 90.00, 107.72, 90.00
R / Rfree (%)	19.2 / 22.2

The structure of Crystal Structure of A Proteolytically Generated Functional Monoferric C-Lobe of Bovine Lactoferrin at 1.9A Resolution also contains other interesting chemical elements:

Iron

(Fe)

1 atom

The binding sites of Zinc atom in the Crystal Structure of A Proteolytically Generated Functional Monoferric C-Lobe of Bovine Lactoferrin at 1.9A Resolution (pdb code 1nkx). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of A Proteolytically Generated Functional Monoferric C-Lobe of Bovine Lactoferrin at 1.9A Resolution, PDB code: 1nkx:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of A Proteolytically Generated Functional Monoferric C-Lobe of Bovine Lactoferrin at 1.9A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of A Proteolytically Generated Functional Monoferric C-Lobe of Bovine Lactoferrin at 1.9A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn691 b:28.6 occ:1.00 OE2 A:GLU659 2.2 26.2 1.0 O A:HOH886 2.2 31.2 1.0 OE1 A:GLU659 2.3 21.4 1.0 CD A:GLU659 2.6 24.9 1.0 O A:GLY653 3.9 36.2 1.0 CG A:GLU659 4.1 23.4 1.0 O A:ARG654 4.5 29.1 1.0 CA A:PRO655 4.6 26.2 1.0 CB A:GLU659 4.8 23.9 1.0 N A:THR656 4.9 23.1 1.0 C A:ARG654 5.0 30.4 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of A Proteolytically Generated Functional Monoferric C-Lobe of Bovine Lactoferrin at 1.9A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of A Proteolytically Generated Functional Monoferric C-Lobe of Bovine Lactoferrin at 1.9A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn692 b:32.4 occ:1.00 O A:HOH889 2.0 33.3 1.0 NE2 A:HIS588 2.2 24.5 1.0 O A:HOH888 2.3 36.8 1.0 O A:HOH824 2.6 46.0 1.0 CE1 A:HIS588 3.1 24.7 1.0 CD2 A:HIS588 3.2 24.2 1.0 O A:HOH884 4.0 54.6 1.0 ND1 A:HIS588 4.3 24.3 1.0 CG A:HIS588 4.3 23.4 1.0 CG1 A:VAL591 4.4 32.6 1.0 O A:HOH722 4.6 31.1 1.0

S.Sharma, J.Jasti, J.Kumar, A.K.Mohanty, T.P.Singh. Crystal Structure of A Proteolytically Generated Functional Monoferric C-Lobe of Bovine Lactoferrin at 1.9A Resolution J.Mol.Biol. V. 331 485 2003.
ISSN: ISSN 0022-2836
PubMed: 12888354
DOI: 10.1016/S0022-2836(03)00717-4