Zinc in PDB 1mft: Crystal Structure of Four-Helix Bundle Model

The structure of Crystal Structure of Four-Helix Bundle Model, PDB code: 1mft was solved by S.J.Lahr, S.E.Stayrook, B.North, J.Kaplan, S.Geremia, W.Degrado, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	18.21 / 2.50
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	25.233, 54.810, 37.168, 90.00, 105.08, 90.00
R / Rfree (%)	22.2 / 26.6

The binding sites of Zinc atom in the Crystal Structure of Four-Helix Bundle Model (pdb code 1mft). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Four-Helix Bundle Model, PDB code: 1mft:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Four-Helix Bundle Model


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Four-Helix Bundle Model within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn60 b:27.9 occ:1.00 OE1 A:GLU41 2.0 16.9 1.0 ND1 A:HIS44 2.1 25.1 1.0 OE2 A:GLU11 2.3 24.4 1.0 OE1 A:GLU11 2.4 38.7 1.0 OE2 B:GLU41 2.5 27.3 1.0 CD A:GLU11 2.7 27.2 1.0 CE1 A:HIS44 2.9 16.0 1.0 OE1 B:GLU41 3.0 29.1 1.0 CD B:GLU41 3.0 26.1 1.0 CD A:GLU41 3.2 15.9 1.0 CG A:HIS44 3.3 22.6 1.0 CB A:HIS44 3.7 18.8 1.0 OE2 A:GLU41 3.8 14.1 1.0 ZN B:ZN60 4.0 30.7 1.0 CA A:GLU41 4.1 18.8 1.0 NE2 A:HIS44 4.1 17.4 1.0 CG A:GLU11 4.2 21.2 1.0 CG2 B:ILE37 4.2 19.1 1.0 CD2 A:HIS44 4.3 9.9 1.0 CG B:GLU41 4.3 21.6 1.0 CG A:GLU41 4.4 12.3 1.0 CB A:GLU41 4.4 18.6 1.0 OH B:TYR18 4.5 18.6 1.0 CE1 B:HIS44 4.6 26.4 1.0 CE1 B:TYR18 4.7 27.1 1.0 O A:ASP40 4.8 20.6 1.0 ND1 B:HIS44 4.8 19.6 1.0 N A:GLU41 4.8 19.3 1.0 O A:GLU41 4.9 22.9 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Four-Helix Bundle Model


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Four-Helix Bundle Model within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn60 b:30.7 occ:1.00 ND1 B:HIS44 2.0 19.6 1.0 OE2 A:GLU41 2.1 14.1 1.0 OE2 B:GLU11 2.2 42.1 1.0 OE1 B:GLU11 2.3 30.9 1.0 CD B:GLU11 2.6 33.6 1.0 OE1 B:GLU41 2.7 29.1 1.0 CE1 B:HIS44 2.9 26.4 1.0 CD A:GLU41 3.0 15.9 1.0 CG B:HIS44 3.1 22.0 1.0 CD B:GLU41 3.2 26.1 1.0 OE2 B:GLU41 3.2 27.3 1.0 OE1 A:GLU41 3.3 16.9 1.0 CB B:HIS44 3.5 19.3 1.0 ZN A:ZN60 4.0 27.9 1.0 NE2 B:HIS44 4.0 27.1 1.0 CG B:GLU11 4.1 27.5 1.0 CA B:GLU41 4.1 17.7 1.0 CD2 B:HIS44 4.1 26.6 1.0 CG2 A:ILE37 4.4 19.6 1.0 CG A:GLU41 4.4 12.3 1.0 CG B:GLU41 4.4 21.6 1.0 OH A:TYR18 4.5 30.5 1.0 CB B:GLU41 4.5 14.0 1.0 CE1 A:TYR18 4.8 30.3 1.0 N B:GLU41 4.8 19.6 1.0 O B:GLU41 4.8 17.8 1.0 CB B:GLU11 4.9 25.9 1.0 O B:ASP40 4.9 20.1 1.0 CA B:HIS44 5.0 23.5 1.0

S.J.Lahr, D.E.Engel, S.E.Stayrook, O.Maglio, B.North, S.Geremia, A.Lombardi, W.F.Degrado. Analysis and Design of Turns in Alpha-Helical Hairpins J.Mol.Biol. V. 346 1441 2005.
ISSN: ISSN 0022-2836
PubMed: 15713492
DOI: 10.1016/J.JMB.2004.12.016