Zinc in PDB 1m4m: Mouse Survivin

The structure of Mouse Survivin, PDB code: 1m4m was solved by S.W.Muchmore, J.Chen, C.Jakob, D.Zakula, E.D.Matayoshi, W.Wu, H.Zhang, F.Li, S.C.Ng, D.C.Altieri, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.80
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	41.430, 41.430, 291.340, 90.00, 90.00, 120.00
R / Rfree (%)	n/a / n/a

The binding sites of Zinc atom in the Mouse Survivin (pdb code 1m4m). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Mouse Survivin, PDB code: 1m4m:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Mouse Survivin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Mouse Survivin within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:44.8 occ:0.50 NE2 A:HIS80 1.8 45.0 1.0 OE2 A:GLU76 2.2 52.9 1.0 CD2 A:HIS80 2.8 41.4 1.0 CE1 A:HIS80 2.8 43.4 1.0 CD A:GLU76 3.1 52.2 1.0 CG A:GLU76 3.7 51.9 1.0 CG A:HIS80 3.9 41.3 1.0 ND1 A:HIS80 3.9 41.8 1.0 CD A:LYS79 3.9 42.6 1.0 OE1 A:GLU76 4.0 54.2 1.0 CE A:LYS79 4.8 45.2 1.0 CD1 A:LEU64 5.0 47.4 1.0

Zinc binding site 2 out of 2 in the Mouse Survivin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Mouse Survivin within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn502 b:41.0 occ:1.00 NE2 A:HIS77 2.1 46.5 1.0 SG A:CYS84 2.3 40.0 1.0 SG A:CYS57 2.3 42.1 1.0 SG A:CYS60 2.3 60.0 1.0 CE1 A:HIS77 2.7 47.5 1.0 CB A:CYS60 2.8 53.3 1.0 CB A:CYS57 3.0 42.5 1.0 CB A:CYS84 3.2 43.9 1.0 CD2 A:HIS77 3.4 45.8 1.0 N A:CYS60 3.5 55.1 1.0 CA A:CYS60 3.7 54.0 1.0 ND1 A:HIS77 3.9 45.2 1.0 CG A:HIS77 4.3 45.8 1.0 OG A:SER81 4.3 35.8 1.0 CA A:CYS57 4.5 43.6 1.0 CB A:PHE59 4.5 53.9 1.0 CA A:CYS84 4.5 47.4 1.0 C A:PHE59 4.6 53.5 1.0 CB A:SER81 4.8 41.3 1.0 C A:CYS60 4.9 52.4 1.0 CG A:LEU87 4.9 56.2 1.0 CA A:PHE59 5.0 52.0 1.0

S.W.Muchmore, J.Chen, C.Jakob, D.Zakula, E.D.Matayoshi, W.Wu, H.Zhang, F.Li, S.C.Ng, D.C.Altieri. Crystal Structure and Mutagenic Analysis of the Inhibitor-of-Apoptosis Protein Survivin Mol.Cell V. 6 173 2000.
ISSN: ISSN 1097-2765
PubMed: 10949038
DOI: 10.1016/S1097-2765(00)00018-6