Zinc in PDB 1l3e: uc(Nmr) Structures of the Hif-1ALPHA Ctad/P300 CH1 Complex

The binding sites of Zinc atom in the uc(Nmr) Structures of the Hif-1ALPHA Ctad/P300 CH1 Complex (pdb code 1l3e). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the uc(Nmr) Structures of the Hif-1ALPHA Ctad/P300 CH1 Complex, PDB code: 1l3e:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the uc(Nmr) Structures of the Hif-1ALPHA Ctad/P300 CH1 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of uc(Nmr) Structures of the Hif-1ALPHA Ctad/P300 CH1 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn202 b:0.0 occ:1.00 NE2 B:HIS125 2.0 0.0 1.0 SG B:CYS129 2.3 0.0 1.0 SG B:CYS147 2.3 0.0 1.0 SG B:CYS142 2.3 0.0 1.0 HB2 B:CYS147 2.5 0.0 1.0 HB3 B:CYS147 2.5 0.0 1.0 CB B:CYS147 2.6 0.0 1.0 CE1 B:HIS125 3.0 0.0 1.0 CD2 B:HIS125 3.1 0.0 1.0 HE1 B:HIS125 3.2 0.0 1.0 HB2 B:LEU144 3.3 0.0 1.0 HD2 B:HIS125 3.4 0.0 1.0 CB B:CYS129 3.6 0.0 1.0 HD11 B:LEU144 3.6 0.0 1.0 HB2 B:CYS129 3.7 0.0 1.0 HB3 B:CYS129 3.7 0.0 1.0 HB3 B:LEU144 3.8 0.0 1.0 CB B:CYS142 3.8 0.0 1.0 HB2 B:CYS142 3.9 0.0 1.0 CB B:LEU144 4.0 0.0 1.0 CA B:CYS147 4.1 0.0 1.0 ND1 B:HIS125 4.2 0.0 1.0 HE3 B:LYS151 4.2 0.0 1.0 HB3 B:CYS142 4.2 0.0 1.0 CG B:HIS125 4.3 0.0 1.0 HD22 B:LEU144 4.3 0.0 1.0 HA B:ALA126 4.3 0.0 1.0 H B:ARG148 4.3 0.0 1.0 HA B:CYS147 4.5 0.0 1.0 CD1 B:LEU144 4.5 0.0 1.0 H B:CYS147 4.6 0.0 1.0 CG B:LEU144 4.7 0.0 1.0 HD21 B:LEU144 4.8 0.0 1.0 C B:CYS147 4.8 0.0 1.0 N B:ARG148 4.8 0.0 1.0 HD2 B:LYS151 4.8 0.0 1.0 O B:LEU144 4.8 0.0 1.0 CD2 B:LEU144 4.8 0.0 1.0 N B:CYS147 4.8 0.0 1.0 HZ2 B:LYS151 4.9 0.0 1.0 HD13 B:LEU144 4.9 0.0 1.0 CA B:CYS129 5.0 0.0 1.0

Zinc binding site 2 out of 3 in the uc(Nmr) Structures of the Hif-1ALPHA Ctad/P300 CH1 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of uc(Nmr) Structures of the Hif-1ALPHA Ctad/P300 CH1 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn203 b:0.0 occ:1.00 HE1 B:HIS156 2.0 0.0 1.0 NE2 B:HIS156 2.0 0.0 1.0 CE1 B:HIS156 2.1 0.0 1.0 SG B:CYS160 2.3 0.0 1.0 SG B:CYS171 2.4 0.0 1.0 SG B:CYS166 2.4 0.0 1.0 HB3 B:CYS171 2.6 0.0 1.0 CB B:CYS171 2.8 0.0 1.0 HB3 B:CYS166 2.8 0.0 1.0 HB2 B:CYS160 2.9 0.0 1.0 HB B:VAL168 2.9 0.0 1.0 HB2 B:CYS171 2.9 0.0 1.0 CB B:CYS166 3.1 0.0 1.0 CD2 B:HIS156 3.1 0.0 1.0 ND1 B:HIS156 3.2 0.0 1.0 CB B:CYS160 3.2 0.0 1.0 HB2 B:CYS166 3.4 0.0 1.0 H B:GLN167 3.6 0.0 1.0 HG21 B:VAL168 3.6 0.0 1.0 H B:VAL168 3.7 0.0 1.0 CG B:HIS156 3.7 0.0 1.0 HB3 B:CYS160 3.8 0.0 1.0 HD1 B:HIS156 3.8 0.0 1.0 HD2 B:HIS156 3.9 0.0 1.0 CB B:VAL168 3.9 0.0 1.0 CG2 B:VAL168 4.2 0.0 1.0 H B:ALA172 4.2 0.0 1.0 CA B:CYS171 4.3 0.0 1.0 N B:VAL168 4.3 0.0 1.0 HA B:MET157 4.4 0.0 1.0 HA B:CYS160 4.4 0.0 1.0 N B:GLN167 4.4 0.0 1.0 CA B:CYS160 4.5 0.0 1.0 CA B:CYS166 4.5 0.0 1.0 HG23 B:VAL168 4.5 0.0 1.0 O B:VAL168 4.6 0.0 1.0 HG12 B:VAL168 4.6 0.0 1.0 CA B:VAL168 4.6 0.0 1.0 N B:ALA172 4.7 0.0 1.0 HA B:CYS171 4.7 0.0 1.0 H B:GLY163 4.8 0.0 1.0 C B:CYS171 4.8 0.0 1.0 HA B:CYS166 4.8 0.0 1.0 CG1 B:VAL168 4.9 0.0 1.0 H B:CYS171 4.9 0.0 1.0 C B:CYS166 4.9 0.0 1.0

Zinc binding site 3 out of 3 in the uc(Nmr) Structures of the Hif-1ALPHA Ctad/P300 CH1 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of uc(Nmr) Structures of the Hif-1ALPHA Ctad/P300 CH1 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn204 b:0.0 occ:1.00 NE2 B:HIS180 2.1 0.0 1.0 SG B:CYS189 2.4 0.0 1.0 SG B:CYS192 2.4 0.0 1.0 SG B:CYS184 2.4 0.0 1.0 HB2 B:CYS184 2.5 0.0 1.0 HB3 B:CYS189 2.6 0.0 1.0 CE1 B:HIS180 2.6 0.0 1.0 CB B:CYS184 2.8 0.0 1.0 HE1 B:HIS180 2.8 0.0 1.0 CD2 B:HIS180 3.0 0.0 1.0 HB3 B:CYS184 3.0 0.0 1.0 CB B:CYS189 3.0 0.0 1.0 HA B:TRP181 3.4 0.0 1.0 HD2 B:HIS180 3.5 0.0 1.0 ND1 B:HIS180 3.6 0.0 1.0 HA B:CYS189 3.6 0.0 1.0 HB2 B:CYS192 3.7 0.0 1.0 H B:CYS192 3.8 0.0 1.0 CB B:CYS192 3.8 0.0 1.0 CG B:HIS180 3.8 0.0 1.0 HB2 B:CYS189 3.8 0.0 1.0 CA B:CYS189 3.9 0.0 1.0 O B:HIS180 4.2 0.0 1.0 CA B:CYS184 4.3 0.0 1.0 CA B:TRP181 4.3 0.0 1.0 HD1 B:HIS180 4.4 0.0 1.0 HB3 B:CYS192 4.4 0.0 1.0 O B:TRP181 4.5 0.0 1.0 HA B:CYS184 4.5 0.0 1.0 HD2 B:PRO190 4.5 0.0 1.0 C B:HIS180 4.5 0.0 1.0 HB3 A:ALA20 4.5 0.0 1.0 N B:CYS192 4.5 0.0 1.0 HB B:VAL191 4.6 0.0 1.0 N B:TRP181 4.6 0.0 1.0 H B:VAL191 4.7 0.0 1.0 HB1 A:ALA20 4.8 0.0 1.0 H B:CYS184 4.8 0.0 1.0 CA B:CYS192 4.8 0.0 1.0 C B:CYS189 4.9 0.0 1.0 C B:TRP181 4.9 0.0 1.0 N B:CYS189 5.0 0.0 1.0 H B:CYS189 5.0 0.0 1.0

S.J.Freedman, Z.Y.Sun, F.Poy, A.L.Kung, D.M.Livingston, G.Wagner, M.J.Eck. Structural Basis For Recruitment of Cbp/P300 By Hypoxia-Inducible Factor-1 Alpha. Proc.Natl.Acad.Sci.Usa V. 99 5367 2002.
ISSN: ISSN 0027-8424
PubMed: 11959990
DOI: 10.1073/PNAS.082117899