Zinc in PDB 1j73: Crystal Structure of An Unstable Insulin Analog with Native Activity.

The structure of Crystal Structure of An Unstable Insulin Analog with Native Activity., PDB code: 1j73 was solved by Z.Wan, M.Zhao, S.Nakagawa, W.Jia, M.A.Weiss, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 2.00
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	79.220, 79.220, 36.884, 90.00, 90.00, 120.00
R / Rfree (%)	20.5 / 27.3

The binding sites of Zinc atom in the Crystal Structure of An Unstable Insulin Analog with Native Activity. (pdb code 1j73). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of An Unstable Insulin Analog with Native Activity., PDB code: 1j73:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of An Unstable Insulin Analog with Native Activity.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of An Unstable Insulin Analog with Native Activity. within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn31 b:2.0 occ:0.33 NE2 B:HIS10 2.2 13.7 1.0 CE1 B:HIS10 3.1 8.5 1.0 CD2 B:HIS10 3.1 8.7 1.0 ND1 B:HIS10 4.2 14.5 1.0 CG B:HIS10 4.3 9.8 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of An Unstable Insulin Analog with Native Activity.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of An Unstable Insulin Analog with Native Activity. within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn31 b:2.0 occ:0.33 NE2 D:HIS10 2.1 12.6 1.0 CE1 D:HIS10 3.0 15.2 1.0 CD2 D:HIS10 3.1 5.9 1.0 ND1 D:HIS10 4.2 11.8 1.0 CG D:HIS10 4.2 9.2 1.0 O D:LEU6 4.4 15.9 1.0 CB D:LEU6 4.7 13.2 1.0 O D:HOH37 4.8 29.9 1.0

M.A.Weiss, Z.Wan, M.Zhao, Y.C.Chu, S.H.Nakagawa, G.T.Burke, W.Jia, R.Hellmich, P.G.Katsoyannis. Non-Standard Insulin Design: Structure-Activity Relationships at the Periphery of the Insulin Receptor. J.Mol.Biol. V. 315 103 2002.
ISSN: ISSN 0022-2836
PubMed: 11779231
DOI: 10.1006/JMBI.2001.5224