Zinc in PDB 1j2u: Creatininase Zn
Enzymatic activity of Creatininase Zn
All present enzymatic activity of Creatininase Zn:
3.5.2.10;
Protein crystallography data
The structure of Creatininase Zn, PDB code: 1j2u
was solved by
T.Yoshimoto,
N.Tanaka,
N.Kanada,
T.Inoue,
Y.Nakajima,
M.Haratake,
K.T.Nakamura,
Y.Xu,
K.Ito,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
40.00 /
1.85
|
|
Space group
|
P 21 21 21
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
102.114,
151.449,
167.633,
90.00,
90.00,
90.00
|
|
R / Rfree (%)
|
18.6 /
20.1
|
Zinc Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
12;
Binding sites:
The binding sites of Zinc atom in the Creatininase Zn
(pdb code 1j2u). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 12 binding sites of Zinc where determined in the
Creatininase Zn, PDB code: 1j2u:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Zinc binding site 1 out
of 12 in 1j2u
Go back to
Zinc Binding Sites List in 1j2u
Zinc binding site 1 out
of 12 in the Creatininase Zn
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Creatininase Zn within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn302
b:22.1
occ:1.00
|
O
|
A:HOH8008
|
1.8
|
24.9
|
1.0
|
|
OD1
|
A:ASP45
|
2.0
|
20.0
|
1.0
|
|
OE1
|
A:GLU183
|
2.0
|
22.7
|
1.0
|
|
NE2
|
A:HIS36
|
2.0
|
20.2
|
1.0
|
|
CD
|
A:GLU183
|
2.7
|
21.7
|
1.0
|
|
OE2
|
A:GLU183
|
2.8
|
20.9
|
1.0
|
|
CG
|
A:ASP45
|
2.9
|
19.0
|
1.0
|
|
CE1
|
A:HIS36
|
3.0
|
19.8
|
1.0
|
|
OD2
|
A:ASP45
|
3.1
|
18.9
|
1.0
|
|
CD2
|
A:HIS36
|
3.1
|
21.0
|
1.0
|
|
O
|
A:HOH8013
|
3.1
|
37.4
|
1.0
|
|
ZN
|
A:ZN301
|
3.6
|
42.8
|
1.0
|
|
O
|
A:HOH8010
|
3.9
|
31.0
|
1.0
|
|
O
|
A:HOH8011
|
3.9
|
22.0
|
1.0
|
|
ND1
|
A:HIS178
|
4.0
|
21.6
|
1.0
|
|
CG1
|
A:VAL44
|
4.0
|
21.5
|
1.0
|
|
ND1
|
A:HIS36
|
4.1
|
21.1
|
1.0
|
|
O
|
A:HOH8251
|
4.1
|
32.5
|
1.0
|
|
CG
|
A:HIS36
|
4.2
|
21.3
|
1.0
|
|
CG
|
A:GLU183
|
4.2
|
21.9
|
1.0
|
|
CE1
|
A:HIS178
|
4.3
|
19.9
|
1.0
|
|
CB
|
A:ASP45
|
4.3
|
18.9
|
1.0
|
|
OE2
|
A:GLU34
|
4.3
|
20.9
|
1.0
|
|
O
|
A:GLY119
|
4.5
|
19.5
|
1.0
|
|
N
|
A:ASP45
|
4.6
|
19.2
|
1.0
|
|
CB
|
A:VAL44
|
4.6
|
20.3
|
1.0
|
|
CA
|
A:ASP45
|
4.7
|
19.3
|
1.0
|
|
O
|
A:HOH8027
|
5.0
|
17.3
|
1.0
|
|
Zinc binding site 2 out
of 12 in 1j2u
Go back to
Zinc Binding Sites List in 1j2u
Zinc binding site 2 out
of 12 in the Creatininase Zn
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Creatininase Zn within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn301
b:42.8
occ:1.00
|
O
|
A:HOH8010
|
1.8
|
31.0
|
1.0
|
|
OE2
|
A:GLU34
|
2.0
|
20.9
|
1.0
|
|
OD2
|
A:ASP45
|
2.0
|
18.9
|
1.0
|
|
ND1
|
A:HIS120
|
2.3
|
16.4
|
1.0
|
|
O
|
A:HOH8009
|
2.6
|
32.8
|
1.0
|
|
O
|
A:HOH8008
|
2.8
|
24.9
|
1.0
|
|
CD
|
A:GLU34
|
3.1
|
19.8
|
1.0
|
|
CE1
|
A:HIS120
|
3.1
|
20.3
|
1.0
|
|
CG
|
A:ASP45
|
3.2
|
19.0
|
1.0
|
|
CG
|
A:HIS120
|
3.4
|
18.8
|
1.0
|
|
OE1
|
A:GLU34
|
3.5
|
23.1
|
1.0
|
|
ZN
|
A:ZN302
|
3.6
|
22.1
|
1.0
|
|
OD1
|
A:ASP45
|
3.7
|
20.0
|
1.0
|
|
CA
|
A:HIS120
|
3.8
|
18.6
|
1.0
|
|
O
|
A:HOH8013
|
3.8
|
37.4
|
1.0
|
|
CB
|
A:HIS120
|
3.9
|
18.1
|
1.0
|
|
OE1
|
A:GLU122
|
4.1
|
23.3
|
1.0
|
|
N
|
A:TYR121
|
4.1
|
18.7
|
1.0
|
|
NE2
|
A:HIS120
|
4.3
|
17.5
|
1.0
|
|
ND1
|
A:HIS178
|
4.3
|
21.6
|
1.0
|
|
CG
|
A:GLU34
|
4.3
|
20.0
|
1.0
|
|
CE1
|
A:HIS36
|
4.4
|
19.8
|
1.0
|
|
CB
|
A:ASP45
|
4.4
|
18.9
|
1.0
|
|
CE1
|
A:HIS178
|
4.4
|
19.9
|
1.0
|
|
C
|
A:HIS120
|
4.4
|
18.4
|
1.0
|
|
NE2
|
A:HIS36
|
4.4
|
20.2
|
1.0
|
|
CD2
|
A:HIS120
|
4.5
|
19.5
|
1.0
|
|
CB
|
A:GLU34
|
4.5
|
19.2
|
1.0
|
|
O
|
A:GLY119
|
4.6
|
19.5
|
1.0
|
|
CB
|
A:ALA32
|
4.9
|
16.6
|
1.0
|
|
O
|
A:HOH8251
|
4.9
|
32.5
|
1.0
|
|
N
|
A:HIS120
|
5.0
|
18.5
|
1.0
|
|
Zinc binding site 3 out
of 12 in 1j2u
Go back to
Zinc Binding Sites List in 1j2u
Zinc binding site 3 out
of 12 in the Creatininase Zn
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Creatininase Zn within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn302
b:24.6
occ:1.00
|
O
|
B:HOH8009
|
1.7
|
22.4
|
1.0
|
|
OE1
|
B:GLU183
|
1.8
|
24.1
|
1.0
|
|
NE2
|
B:HIS36
|
2.0
|
25.2
|
1.0
|
|
OD1
|
B:ASP45
|
2.0
|
22.6
|
1.0
|
|
CD
|
B:GLU183
|
2.6
|
23.4
|
1.0
|
|
OE2
|
B:GLU183
|
2.8
|
22.4
|
1.0
|
|
CE1
|
B:HIS36
|
2.9
|
23.7
|
1.0
|
|
CG
|
B:ASP45
|
2.9
|
21.1
|
1.0
|
|
OD2
|
B:ASP45
|
3.0
|
22.7
|
1.0
|
|
CD2
|
B:HIS36
|
3.0
|
23.7
|
1.0
|
|
ZN
|
B:ZN301
|
3.6
|
43.7
|
1.0
|
|
ND1
|
B:HIS178
|
3.8
|
26.2
|
1.0
|
|
O
|
B:HOH8013
|
3.9
|
57.4
|
1.0
|
|
O
|
B:HOH8012
|
3.9
|
25.6
|
1.0
|
|
ND1
|
B:HIS36
|
4.0
|
23.7
|
1.0
|
|
CG1
|
B:VAL44
|
4.1
|
23.6
|
1.0
|
|
CG
|
B:GLU183
|
4.1
|
25.2
|
1.0
|
|
CE1
|
B:HIS178
|
4.1
|
25.3
|
1.0
|
|
O
|
B:HOH8011
|
4.1
|
39.7
|
1.0
|
|
CG
|
B:HIS36
|
4.1
|
23.6
|
1.0
|
|
OE2
|
B:GLU34
|
4.3
|
24.6
|
1.0
|
|
CB
|
B:ASP45
|
4.3
|
21.1
|
1.0
|
|
O
|
B:GLY119
|
4.5
|
20.1
|
1.0
|
|
CB
|
B:VAL44
|
4.6
|
22.3
|
1.0
|
|
N
|
B:ASP45
|
4.6
|
21.0
|
1.0
|
|
CA
|
B:ASP45
|
4.7
|
20.6
|
1.0
|
|
O
|
B:HOH8047
|
5.0
|
20.4
|
1.0
|
|
Zinc binding site 4 out
of 12 in 1j2u
Go back to
Zinc Binding Sites List in 1j2u
Zinc binding site 4 out
of 12 in the Creatininase Zn
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Creatininase Zn within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn301
b:43.7
occ:1.00
|
OE2
|
B:GLU34
|
2.0
|
24.6
|
1.0
|
|
OD2
|
B:ASP45
|
2.0
|
22.7
|
1.0
|
|
O
|
B:HOH8011
|
2.1
|
39.7
|
1.0
|
|
ND1
|
B:HIS120
|
2.3
|
20.6
|
1.0
|
|
O
|
B:HOH8010
|
2.4
|
31.8
|
1.0
|
|
O
|
B:HOH8009
|
2.6
|
22.4
|
1.0
|
|
CD
|
B:GLU34
|
3.0
|
21.7
|
1.0
|
|
CE1
|
B:HIS120
|
3.1
|
21.5
|
1.0
|
|
CG
|
B:ASP45
|
3.2
|
21.1
|
1.0
|
|
CG
|
B:HIS120
|
3.5
|
21.4
|
1.0
|
|
OE1
|
B:GLU34
|
3.5
|
23.9
|
1.0
|
|
ZN
|
B:ZN302
|
3.6
|
24.6
|
1.0
|
|
OD1
|
B:ASP45
|
3.7
|
22.6
|
1.0
|
|
CB
|
B:HIS120
|
3.9
|
22.0
|
1.0
|
|
CA
|
B:HIS120
|
3.9
|
22.3
|
1.0
|
|
OE1
|
B:GLU122
|
4.2
|
23.1
|
1.0
|
|
ND1
|
B:HIS178
|
4.3
|
26.2
|
1.0
|
|
CE1
|
B:HIS178
|
4.3
|
25.3
|
1.0
|
|
CG
|
B:GLU34
|
4.3
|
21.9
|
1.0
|
|
CE1
|
B:HIS36
|
4.3
|
23.7
|
1.0
|
|
CB
|
B:ASP45
|
4.3
|
21.1
|
1.0
|
|
NE2
|
B:HIS120
|
4.3
|
21.0
|
1.0
|
|
N
|
B:TYR121
|
4.4
|
24.0
|
1.0
|
|
NE2
|
B:HIS36
|
4.5
|
25.2
|
1.0
|
|
CD2
|
B:HIS120
|
4.5
|
21.0
|
1.0
|
|
CB
|
B:GLU34
|
4.5
|
20.6
|
1.0
|
|
O
|
B:GLY119
|
4.6
|
20.1
|
1.0
|
|
C
|
B:HIS120
|
4.6
|
23.2
|
1.0
|
|
CB
|
B:ALA32
|
4.8
|
18.0
|
1.0
|
|
O
|
B:HOH8013
|
4.9
|
57.4
|
1.0
|
|
Zinc binding site 5 out
of 12 in 1j2u
Go back to
Zinc Binding Sites List in 1j2u
Zinc binding site 5 out
of 12 in the Creatininase Zn
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of Creatininase Zn within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn302
b:25.6
occ:1.00
|
OE1
|
C:GLU183
|
2.0
|
25.5
|
1.0
|
|
NE2
|
C:HIS36
|
2.0
|
21.0
|
1.0
|
|
O
|
C:HOH8010
|
2.0
|
26.4
|
1.0
|
|
OD1
|
C:ASP45
|
2.0
|
22.4
|
1.0
|
|
CD
|
C:GLU183
|
2.7
|
23.4
|
1.0
|
|
OE2
|
C:GLU183
|
2.9
|
22.9
|
1.0
|
|
CE1
|
C:HIS36
|
2.9
|
22.3
|
1.0
|
|
CG
|
C:ASP45
|
3.0
|
21.6
|
1.0
|
|
CD2
|
C:HIS36
|
3.1
|
21.9
|
1.0
|
|
OD2
|
C:ASP45
|
3.2
|
19.9
|
1.0
|
|
ZN
|
C:ZN301
|
3.7
|
43.3
|
1.0
|
|
ND1
|
C:HIS178
|
3.8
|
23.0
|
1.0
|
|
O
|
C:HOH8013
|
3.8
|
27.8
|
1.0
|
|
ND1
|
C:HIS36
|
4.0
|
22.6
|
1.0
|
|
CG1
|
C:VAL44
|
4.1
|
22.1
|
1.0
|
|
CE1
|
C:HIS178
|
4.1
|
23.3
|
1.0
|
|
CG
|
C:HIS36
|
4.1
|
22.4
|
1.0
|
|
CG
|
C:GLU183
|
4.2
|
25.1
|
1.0
|
|
OE2
|
C:GLU34
|
4.3
|
21.8
|
1.0
|
|
CB
|
C:ASP45
|
4.3
|
20.2
|
1.0
|
|
O
|
C:HOH8012
|
4.4
|
42.6
|
1.0
|
|
O
|
C:GLY119
|
4.5
|
23.8
|
1.0
|
|
CB
|
C:VAL44
|
4.5
|
21.4
|
1.0
|
|
N
|
C:ASP45
|
4.6
|
20.7
|
1.0
|
|
CA
|
C:ASP45
|
4.7
|
20.6
|
1.0
|
|
O
|
C:HOH8011
|
5.0
|
32.4
|
1.0
|
|
Zinc binding site 6 out
of 12 in 1j2u
Go back to
Zinc Binding Sites List in 1j2u
Zinc binding site 6 out
of 12 in the Creatininase Zn
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of Creatininase Zn within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn301
b:43.3
occ:1.00
|
OD2
|
C:ASP45
|
2.1
|
19.9
|
1.0
|
|
OE2
|
C:GLU34
|
2.1
|
21.8
|
1.0
|
|
O
|
C:HOH8011
|
2.1
|
32.4
|
1.0
|
|
ND1
|
C:HIS120
|
2.3
|
21.4
|
1.0
|
|
O
|
C:HOH8010
|
2.6
|
26.4
|
1.0
|
|
CD
|
C:GLU34
|
3.1
|
21.1
|
1.0
|
|
CE1
|
C:HIS120
|
3.1
|
22.3
|
1.0
|
|
CG
|
C:ASP45
|
3.2
|
21.6
|
1.0
|
|
CG
|
C:HIS120
|
3.4
|
21.9
|
1.0
|
|
OE1
|
C:GLU34
|
3.4
|
24.8
|
1.0
|
|
ZN
|
C:ZN302
|
3.7
|
25.6
|
1.0
|
|
OD1
|
C:ASP45
|
3.7
|
22.4
|
1.0
|
|
CB
|
C:HIS120
|
3.8
|
22.6
|
1.0
|
|
CA
|
C:HIS120
|
3.9
|
22.7
|
1.0
|
|
O
|
C:HOH8012
|
4.0
|
42.6
|
1.0
|
|
OE1
|
C:GLU122
|
4.1
|
24.8
|
1.0
|
|
ND1
|
C:HIS178
|
4.3
|
23.0
|
1.0
|
|
CE1
|
C:HIS178
|
4.3
|
23.3
|
1.0
|
|
NE2
|
C:HIS120
|
4.3
|
21.1
|
1.0
|
|
CE1
|
C:HIS36
|
4.4
|
22.3
|
1.0
|
|
CG
|
C:GLU34
|
4.4
|
21.3
|
1.0
|
|
CB
|
C:ASP45
|
4.4
|
20.2
|
1.0
|
|
CD2
|
C:HIS120
|
4.5
|
21.4
|
1.0
|
|
NE2
|
C:HIS36
|
4.5
|
21.0
|
1.0
|
|
CB
|
C:GLU34
|
4.6
|
20.0
|
1.0
|
|
O
|
C:GLY119
|
4.6
|
23.8
|
1.0
|
|
N
|
C:TYR121
|
4.8
|
23.1
|
1.0
|
|
C
|
C:HIS120
|
4.8
|
22.9
|
1.0
|
|
CB
|
C:ALA32
|
4.9
|
19.5
|
1.0
|
|
CD
|
C:GLU122
|
5.0
|
23.9
|
1.0
|
|
Zinc binding site 7 out
of 12 in 1j2u
Go back to
Zinc Binding Sites List in 1j2u
Zinc binding site 7 out
of 12 in the Creatininase Zn
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of Creatininase Zn within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn302
b:27.3
occ:1.00
|
OE1
|
D:GLU183
|
1.8
|
30.1
|
1.0
|
|
O
|
D:HOH8002
|
2.0
|
34.4
|
1.0
|
|
NE2
|
D:HIS36
|
2.0
|
23.6
|
1.0
|
|
OD1
|
D:ASP45
|
2.0
|
24.3
|
1.0
|
|
CD
|
D:GLU183
|
2.6
|
28.9
|
1.0
|
|
OE2
|
D:GLU183
|
2.8
|
27.4
|
1.0
|
|
CE1
|
D:HIS36
|
2.9
|
25.2
|
1.0
|
|
CG
|
D:ASP45
|
3.0
|
24.5
|
1.0
|
|
CD2
|
D:HIS36
|
3.0
|
27.5
|
1.0
|
|
OD2
|
D:ASP45
|
3.1
|
24.4
|
1.0
|
|
ZN
|
D:ZN301
|
3.7
|
51.8
|
1.0
|
|
O
|
D:HOH8005
|
3.8
|
28.8
|
1.0
|
|
ND1
|
D:HIS178
|
4.0
|
26.4
|
1.0
|
|
ND1
|
D:HIS36
|
4.0
|
24.8
|
1.0
|
|
CG
|
D:GLU183
|
4.1
|
29.8
|
1.0
|
|
CG1
|
D:VAL44
|
4.1
|
25.0
|
1.0
|
|
CG
|
D:HIS36
|
4.1
|
27.1
|
1.0
|
|
O
|
D:HOH8004
|
4.2
|
34.0
|
1.0
|
|
CE1
|
D:HIS178
|
4.2
|
23.5
|
1.0
|
|
CB
|
D:ASP45
|
4.3
|
24.2
|
1.0
|
|
OE2
|
D:GLU34
|
4.4
|
24.1
|
1.0
|
|
O
|
D:GLY119
|
4.5
|
23.5
|
1.0
|
|
CB
|
D:VAL44
|
4.6
|
24.2
|
1.0
|
|
N
|
D:ASP45
|
4.6
|
24.5
|
1.0
|
|
CA
|
D:ASP45
|
4.7
|
24.1
|
1.0
|
|
CB
|
D:GLU183
|
5.0
|
30.1
|
1.0
|
|
Zinc binding site 8 out
of 12 in 1j2u
Go back to
Zinc Binding Sites List in 1j2u
Zinc binding site 8 out
of 12 in the Creatininase Zn
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 8 of Creatininase Zn within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn301
b:51.8
occ:1.00
|
OE2
|
D:GLU34
|
1.8
|
24.1
|
1.0
|
|
O
|
D:HOH8004
|
1.9
|
34.0
|
1.0
|
|
OD2
|
D:ASP45
|
2.2
|
24.4
|
1.0
|
|
ND1
|
D:HIS120
|
2.3
|
22.6
|
1.0
|
|
O
|
D:HOH8003
|
2.5
|
31.8
|
1.0
|
|
O
|
D:HOH8002
|
2.9
|
34.4
|
1.0
|
|
CD
|
D:GLU34
|
2.9
|
24.0
|
1.0
|
|
CE1
|
D:HIS120
|
3.1
|
25.0
|
1.0
|
|
CG
|
D:ASP45
|
3.3
|
24.5
|
1.0
|
|
OE1
|
D:GLU34
|
3.4
|
25.5
|
1.0
|
|
CG
|
D:HIS120
|
3.5
|
23.6
|
1.0
|
|
ZN
|
D:ZN302
|
3.7
|
27.3
|
1.0
|
|
OD1
|
D:ASP45
|
3.8
|
24.3
|
1.0
|
|
CA
|
D:HIS120
|
3.9
|
23.1
|
1.0
|
|
CB
|
D:HIS120
|
4.0
|
23.3
|
1.0
|
|
OE1
|
D:GLU122
|
4.1
|
28.2
|
1.0
|
|
CG
|
D:GLU34
|
4.2
|
24.7
|
1.0
|
|
CE1
|
D:HIS178
|
4.2
|
23.5
|
1.0
|
|
ND1
|
D:HIS178
|
4.2
|
26.4
|
1.0
|
|
CE1
|
D:HIS36
|
4.2
|
25.2
|
1.0
|
|
N
|
D:TYR121
|
4.2
|
23.0
|
1.0
|
|
NE2
|
D:HIS120
|
4.3
|
23.5
|
1.0
|
|
NE2
|
D:HIS36
|
4.3
|
23.6
|
1.0
|
|
CB
|
D:GLU34
|
4.4
|
24.6
|
1.0
|
|
CD2
|
D:HIS120
|
4.5
|
22.9
|
1.0
|
|
CB
|
D:ASP45
|
4.5
|
24.2
|
1.0
|
|
C
|
D:HIS120
|
4.5
|
23.3
|
1.0
|
|
O
|
D:GLY119
|
4.8
|
23.5
|
1.0
|
|
CB
|
D:ALA32
|
4.9
|
20.8
|
1.0
|
|
Zinc binding site 9 out
of 12 in 1j2u
Go back to
Zinc Binding Sites List in 1j2u
Zinc binding site 9 out
of 12 in the Creatininase Zn
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 9 of Creatininase Zn within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Zn302
b:25.9
occ:1.00
|
OE1
|
E:GLU183
|
1.9
|
27.7
|
1.0
|
|
NE2
|
E:HIS36
|
2.0
|
22.6
|
1.0
|
|
OD1
|
E:ASP45
|
2.0
|
24.7
|
1.0
|
|
O
|
E:HOH8004
|
2.1
|
32.2
|
1.0
|
|
CD
|
E:GLU183
|
2.7
|
25.1
|
1.0
|
|
OE2
|
E:GLU183
|
2.8
|
24.5
|
1.0
|
|
CE1
|
E:HIS36
|
2.9
|
23.8
|
1.0
|
|
CG
|
E:ASP45
|
3.0
|
22.7
|
1.0
|
|
CD2
|
E:HIS36
|
3.1
|
24.1
|
1.0
|
|
OD2
|
E:ASP45
|
3.1
|
21.4
|
1.0
|
|
ZN
|
E:ZN301
|
3.7
|
49.1
|
1.0
|
|
O
|
E:HOH8007
|
3.9
|
25.6
|
1.0
|
|
ND1
|
E:HIS178
|
3.9
|
22.7
|
1.0
|
|
O
|
E:HOH8006
|
4.0
|
34.1
|
1.0
|
|
O
|
E:HOH8008
|
4.0
|
42.1
|
1.0
|
|
ND1
|
E:HIS36
|
4.1
|
23.0
|
1.0
|
|
CG
|
E:GLU183
|
4.1
|
27.8
|
1.0
|
|
CG1
|
E:VAL44
|
4.2
|
23.7
|
1.0
|
|
CG
|
E:HIS36
|
4.2
|
24.1
|
1.0
|
|
CE1
|
E:HIS178
|
4.2
|
20.5
|
1.0
|
|
CB
|
E:ASP45
|
4.4
|
21.6
|
1.0
|
|
OE2
|
E:GLU34
|
4.4
|
22.3
|
1.0
|
|
O
|
E:GLY119
|
4.5
|
22.5
|
1.0
|
|
CB
|
E:VAL44
|
4.6
|
22.3
|
1.0
|
|
N
|
E:ASP45
|
4.6
|
22.0
|
1.0
|
|
CA
|
E:ASP45
|
4.7
|
22.0
|
1.0
|
|
CB
|
E:GLU183
|
5.0
|
27.1
|
1.0
|
|
Zinc binding site 10 out
of 12 in 1j2u
Go back to
Zinc Binding Sites List in 1j2u
Zinc binding site 10 out
of 12 in the Creatininase Zn
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 10 of Creatininase Zn within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Zn301
b:49.1
occ:1.00
|
OE2
|
E:GLU34
|
1.9
|
22.3
|
1.0
|
|
O
|
E:HOH8006
|
1.9
|
34.1
|
1.0
|
|
OD2
|
E:ASP45
|
2.1
|
21.4
|
1.0
|
|
ND1
|
E:HIS120
|
2.3
|
21.3
|
1.0
|
|
O
|
E:HOH8005
|
2.6
|
31.0
|
1.0
|
|
O
|
E:HOH8004
|
2.6
|
32.2
|
1.0
|
|
CD
|
E:GLU34
|
3.0
|
23.0
|
1.0
|
|
CE1
|
E:HIS120
|
3.1
|
22.7
|
1.0
|
|
CG
|
E:ASP45
|
3.3
|
22.7
|
1.0
|
|
OE1
|
E:GLU34
|
3.5
|
24.7
|
1.0
|
|
CG
|
E:HIS120
|
3.5
|
20.7
|
1.0
|
|
ZN
|
E:ZN302
|
3.7
|
25.9
|
1.0
|
|
OD1
|
E:ASP45
|
3.8
|
24.7
|
1.0
|
|
CA
|
E:HIS120
|
3.9
|
21.6
|
1.0
|
|
CB
|
E:HIS120
|
4.0
|
21.9
|
1.0
|
|
OE1
|
E:GLU122
|
4.2
|
25.9
|
1.0
|
|
CG
|
E:GLU34
|
4.2
|
22.8
|
1.0
|
|
ND1
|
E:HIS178
|
4.3
|
22.7
|
1.0
|
|
CE1
|
E:HIS178
|
4.3
|
20.5
|
1.0
|
|
N
|
E:TYR121
|
4.3
|
21.9
|
1.0
|
|
NE2
|
E:HIS120
|
4.3
|
19.6
|
1.0
|
|
CE1
|
E:HIS36
|
4.3
|
23.8
|
1.0
|
|
NE2
|
E:HIS36
|
4.4
|
22.6
|
1.0
|
|
CB
|
E:GLU34
|
4.4
|
22.9
|
1.0
|
|
CB
|
E:ASP45
|
4.5
|
21.6
|
1.0
|
|
CD2
|
E:HIS120
|
4.5
|
18.9
|
1.0
|
|
C
|
E:HIS120
|
4.6
|
21.7
|
1.0
|
|
O
|
E:GLY119
|
4.7
|
22.5
|
1.0
|
|
CB
|
E:ALA32
|
4.9
|
20.4
|
1.0
|
|
Reference:
T.Yoshimoto,
N.Tanaka,
N.Kanada,
T.Inoue,
Y.Nakajima,
M.Haratake,
K.T.Nakamura,
Y.Xu,
K.Ito.
Crystal Structures of Creatininase Reveal the Substrate Binding Site and Provide An Insight Into the Catalytic Mechanism J.Mol.Biol. V. 337 399 2004.
ISSN: ISSN 0022-2836
PubMed: 15003455
DOI: 10.1016/J.JMB.2004.01.022
Page generated: Sun Oct 13 03:18:00 2024
|
