Atomistry » Zinc » PDB 1i96-1im5 » 1if6
Atomistry »
  Zinc »
    PDB 1i96-1im5 »
      1if6 »

Zinc in PDB 1if6: Carbonic Anhydrase II Complexed with 3,5-Difluorobenzenesulfonamide

Enzymatic activity of Carbonic Anhydrase II Complexed with 3,5-Difluorobenzenesulfonamide

All present enzymatic activity of Carbonic Anhydrase II Complexed with 3,5-Difluorobenzenesulfonamide:
4.2.1.1;

Protein crystallography data

The structure of Carbonic Anhydrase II Complexed with 3,5-Difluorobenzenesulfonamide, PDB code: 1if6 was solved by C.-Y.Kim, D.W.Christianson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 2.09
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 43.600, 41.900, 73.500, 90.00, 104.10, 90.00
R / Rfree (%) 21.1 / 29.9

Other elements in 1if6:

The structure of Carbonic Anhydrase II Complexed with 3,5-Difluorobenzenesulfonamide also contains other interesting chemical elements:

Fluorine (F) 2 atoms
Mercury (Hg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Carbonic Anhydrase II Complexed with 3,5-Difluorobenzenesulfonamide (pdb code 1if6). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Carbonic Anhydrase II Complexed with 3,5-Difluorobenzenesulfonamide, PDB code: 1if6:

Zinc binding site 1 out of 1 in 1if6

Go back to Zinc Binding Sites List in 1if6
Zinc binding site 1 out of 1 in the Carbonic Anhydrase II Complexed with 3,5-Difluorobenzenesulfonamide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Carbonic Anhydrase II Complexed with 3,5-Difluorobenzenesulfonamide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn262

b:19.0
occ:1.00
 NP0 A:FBU555 1.8 5.6 1.0
NE2 A:HIS94 1.8 14.0 1.0
NE2 A:HIS96 2.0 9.6 1.0
ND1 A:HIS119 2.1 16.7 1.0
O09 A:FBU555 2.4 11.0 1.0
S07 A:FBU555 2.6 16.8 1.0
CE1 A:HIS94 2.8 3.3 1.0
CE1 A:HIS96 2.9 7.2 1.0
CD2 A:HIS94 3.0 2.5 1.0
CE1 A:HIS119 3.0 4.5 1.0
CD2 A:HIS96 3.2 7.0 1.0
CG A:HIS119 3.2 7.5 1.0
C04 A:FBU555 3.6 15.0 1.0
CB A:HIS119 3.7 2.5 1.0
O08 A:FBU555 3.7 20.4 1.0
OG1 A:THR199 3.8 10.2 1.0
ND1 A:HIS94 3.9 4.0 1.0
CG A:HIS94 4.1 8.4 1.0
ND1 A:HIS96 4.1 5.5 1.0
OE1 A:GLU106 4.2 15.9 1.0
NE2 A:HIS119 4.2 4.0 1.0
C03 A:FBU555 4.2 14.3 1.0
CG A:HIS96 4.3 10.7 1.0
CD2 A:HIS119 4.3 3.5 1.0
C05 A:FBU555 4.5 13.3 1.0

Reference:

C.-Y.Kim, D.W.Christianson. Binding of Fluorine Substituted Benzenesulfonamides to Carbonic Anhydrase II To Be Published.
Page generated: Sun Oct 13 03:06:03 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy