Zinc in PDB 1ici: Crystal Structure of A SIR2 Homolog-Nad Complex

The structure of Crystal Structure of A SIR2 Homolog-Nad Complex, PDB code: 1ici was solved by J.Min, J.Landry, R.Sternglanz, R.-M.Xu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.00 / 2.10
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	65.410, 94.540, 93.780, 90.00, 95.29, 90.00
R / Rfree (%)	19.9 / 24.9

The binding sites of Zinc atom in the Crystal Structure of A SIR2 Homolog-Nad Complex (pdb code 1ici). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of A SIR2 Homolog-Nad Complex, PDB code: 1ici:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of A SIR2 Homolog-Nad Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of A SIR2 Homolog-Nad Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2001 b:17.0 occ:1.00 SG A:CYS127 2.2 19.9 1.0 SG A:CYS148 2.3 17.9 1.0 SG A:CYS145 2.3 20.7 1.0 SG A:CYS124 2.4 14.6 1.0 CB A:CYS145 3.1 19.6 1.0 CB A:CYS124 3.1 17.5 1.0 CB A:CYS148 3.3 17.9 1.0 CB A:CYS127 3.3 22.4 1.0 N A:CYS127 3.6 21.8 1.0 N A:CYS148 3.7 16.6 1.0 CA A:CYS127 4.0 22.9 1.0 CA A:CYS148 4.0 18.1 1.0 CB A:ASN129 4.3 18.7 1.0 CB A:LYS147 4.5 16.5 1.0 C A:CYS127 4.5 26.3 1.0 CA A:CYS145 4.6 18.7 1.0 CA A:CYS124 4.6 18.5 1.0 C A:CYS148 4.6 16.0 1.0 C A:LYS147 4.7 19.6 1.0 CB A:SER150 4.7 17.6 1.0 O A:CYS127 4.7 26.7 1.0 C A:SER126 4.7 21.0 1.0 N A:SER150 4.7 19.3 1.0 CB A:SER126 4.7 20.7 1.0 N A:GLY149 4.8 16.2 1.0 OG A:SER150 4.9 18.8 1.0 N A:SER126 5.0 21.1 1.0 CA A:LYS147 5.0 18.7 1.0 N A:LYS147 5.0 18.0 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of A SIR2 Homolog-Nad Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of A SIR2 Homolog-Nad Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn2002 b:33.4 occ:1.00 SG B:CYS127 2.2 36.6 1.0 SG B:CYS145 2.2 30.2 1.0 SG B:CYS124 2.4 33.4 1.0 SG B:CYS148 2.4 41.9 1.0 CB B:CYS145 3.0 34.9 1.0 CB B:CYS124 3.0 25.3 1.0 CB B:CYS127 3.0 33.3 1.0 CB B:CYS148 3.4 43.3 1.0 N B:CYS127 3.7 33.6 1.0 CA B:CYS127 3.9 33.9 1.0 N B:CYS148 3.9 44.2 1.0 CA B:CYS148 4.2 43.1 1.0 CA B:CYS145 4.5 37.5 1.0 CA B:CYS124 4.5 26.6 1.0 CB B:SER150 4.6 34.8 1.0 C B:CYS127 4.6 35.4 1.0 C B:LYS147 4.7 46.5 1.0 C B:CYS148 4.7 43.0 1.0 N B:SER150 4.7 35.7 1.0 N B:ASN128 4.8 34.7 1.0 CB B:LYS147 4.8 46.5 1.0 OG B:SER150 4.8 32.8 1.0 C B:SER126 4.9 34.0 1.0 N B:GLY149 4.9 41.8 1.0 CB B:SER126 5.0 35.2 1.0 C B:CYS145 5.0 38.7 1.0 N B:ASN129 5.0 28.2 1.0

J.Min, J.Landry, R.Sternglanz, R.M.Xu. Crystal Structure of A SIR2 Homolog-Nad Complex. Cell(Cambridge,Mass.) V. 105 269 2001.
ISSN: ISSN 0092-8674
PubMed: 11336676
DOI: 10.1016/S0092-8674(01)00317-8