Zinc in PDB 1iaj: Crystal Structure of the Atypical Protein Kinase Domain of A Trp Ca-Channel, Chak (Apo)

All present enzymatic activity of Crystal Structure of the Atypical Protein Kinase Domain of A Trp Ca-Channel, Chak (Apo):
2.7.1.37;

The structure of Crystal Structure of the Atypical Protein Kinase Domain of A Trp Ca-Channel, Chak (Apo), PDB code: 1iaj was solved by H.Yamaguchi, M.Matsushita, A.C.Nairn, J.Kuriyan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.80
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	108.270, 138.200, 113.520, 90.00, 90.00, 90.00
R / Rfree (%)	22.9 / 29.2

The binding sites of Zinc atom in the Crystal Structure of the Atypical Protein Kinase Domain of A Trp Ca-Channel, Chak (Apo) (pdb code 1iaj). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the Atypical Protein Kinase Domain of A Trp Ca-Channel, Chak (Apo), PDB code: 1iaj:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of the Atypical Protein Kinase Domain of A Trp Ca-Channel, Chak (Apo)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Atypical Protein Kinase Domain of A Trp Ca-Channel, Chak (Apo) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2001 b:59.4 occ:1.00 NE2 A:HIS1808 1.9 28.1 1.0 ND1 A:HIS1751 2.1 53.4 1.0 SG A:CYS1814 2.2 46.0 1.0 SG A:CYS1810 2.3 58.8 1.0 CE1 A:HIS1808 2.9 28.1 1.0 CB A:CYS1814 2.9 46.0 1.0 CE1 A:HIS1751 2.9 53.4 1.0 CD2 A:HIS1808 3.0 28.1 1.0 CG A:HIS1751 3.1 53.4 1.0 CB A:CYS1810 3.2 58.8 1.0 CA A:CYS1810 3.3 43.5 1.0 CB A:HIS1751 3.6 53.4 1.0 N A:CYS1810 4.0 43.5 1.0 ND1 A:HIS1808 4.0 28.1 1.0 NE2 A:HIS1751 4.1 53.4 1.0 CG A:HIS1808 4.1 28.1 1.0 CD2 A:HIS1751 4.2 53.4 1.0 CA A:CYS1814 4.3 43.0 1.0 C A:CYS1810 4.5 43.5 1.0 N A:ASN1811 4.6 47.0 1.0 C A:HIS1809 4.6 39.5 1.0 O A:HIS1809 4.7 39.5 1.0 CD1 A:LEU1819 4.8 64.2 1.0 CB A:LEU1819 4.8 64.2 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of the Atypical Protein Kinase Domain of A Trp Ca-Channel, Chak (Apo)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Atypical Protein Kinase Domain of A Trp Ca-Channel, Chak (Apo) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn2001 b:59.4 occ:1.00 NE2 B:HIS1808 2.0 41.6 1.0 ND1 B:HIS1751 2.0 60.7 1.0 SG B:CYS1814 2.3 50.8 1.0 SG B:CYS1810 2.4 71.8 1.0 CE1 B:HIS1751 2.9 60.7 1.0 CE1 B:HIS1808 3.0 41.6 1.0 CG B:HIS1751 3.1 60.7 1.0 CD2 B:HIS1808 3.1 41.6 1.0 CB B:CYS1814 3.1 50.8 1.0 CB B:CYS1810 3.3 71.8 1.0 CA B:CYS1810 3.3 77.8 1.0 CB B:HIS1751 3.5 60.7 1.0 NE2 B:HIS1751 4.0 60.7 1.0 CD2 B:HIS1751 4.1 60.7 1.0 N B:CYS1810 4.1 77.8 1.0 ND1 B:HIS1808 4.2 41.6 1.0 CG B:HIS1808 4.2 41.6 1.0 CA B:CYS1814 4.4 73.4 1.0 C B:CYS1810 4.5 77.8 1.0 N B:ASN1811 4.5 56.5 1.0 CD1 B:LEU1819 4.7 70.3 1.0 C B:HIS1809 4.8 53.9 1.0 O B:HIS1809 4.8 53.9 1.0

H.Yamaguchi, M.Matsushita, A.C.Nairn, J.Kuriyan. Crystal Structure of the Atypical Protein Kinase Domain of A Trp Channel with Phosphotransferase Activity. Mol.Cell V. 7 1047 2001.
ISSN: ISSN 1097-2765
PubMed: 11389851
DOI: 10.1016/S1097-2765(01)00256-8