Zinc in PDB 1iah: Crystal Structure of the Atypical Protein Kinase Domain of A Trp Ca-Channel, Chak (Adp-Mg Complex)

All present enzymatic activity of Crystal Structure of the Atypical Protein Kinase Domain of A Trp Ca-Channel, Chak (Adp-Mg Complex):
2.7.1.37;

The structure of Crystal Structure of the Atypical Protein Kinase Domain of A Trp Ca-Channel, Chak (Adp-Mg Complex), PDB code: 1iah was solved by H.Yamaguchi, M.Matsushita, A.C.Nairn, J.Kuriyan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.40
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	108.961, 135.458, 113.204, 90.00, 90.00, 90.00
R / Rfree (%)	21.5 / 24.9

The structure of Crystal Structure of the Atypical Protein Kinase Domain of A Trp Ca-Channel, Chak (Adp-Mg Complex) also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Crystal Structure of the Atypical Protein Kinase Domain of A Trp Ca-Channel, Chak (Adp-Mg Complex) (pdb code 1iah). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the Atypical Protein Kinase Domain of A Trp Ca-Channel, Chak (Adp-Mg Complex), PDB code: 1iah:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of the Atypical Protein Kinase Domain of A Trp Ca-Channel, Chak (Adp-Mg Complex)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Atypical Protein Kinase Domain of A Trp Ca-Channel, Chak (Adp-Mg Complex) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2001 b:40.8 occ:1.00 NE2 A:HIS1808 2.0 36.9 1.0 ND1 A:HIS1751 2.2 46.2 1.0 SG A:CYS1814 2.2 44.5 1.0 SG A:CYS1810 2.4 50.3 1.0 CE1 A:HIS1751 3.0 43.0 1.0 CE1 A:HIS1808 3.0 38.0 1.0 CD2 A:HIS1808 3.1 36.1 1.0 CB A:CYS1814 3.1 45.1 1.0 CG A:HIS1751 3.2 46.3 1.0 CB A:CYS1810 3.2 48.4 1.0 CA A:CYS1810 3.3 48.1 1.0 CB A:HIS1751 3.6 39.4 1.0 N A:CYS1810 4.0 47.5 1.0 NE2 A:HIS1751 4.1 47.2 1.0 ND1 A:HIS1808 4.2 35.5 1.0 CD2 A:HIS1751 4.2 46.3 1.0 CG A:HIS1808 4.2 38.1 1.0 CA A:CYS1814 4.4 46.6 1.0 C A:CYS1810 4.5 49.6 1.0 N A:ASN1811 4.6 46.7 1.0 CD1 A:LEU1819 4.6 46.2 1.0 C A:HIS1809 4.6 50.0 1.0 O A:HIS1809 4.7 50.4 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of the Atypical Protein Kinase Domain of A Trp Ca-Channel, Chak (Adp-Mg Complex)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Atypical Protein Kinase Domain of A Trp Ca-Channel, Chak (Adp-Mg Complex) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn2001 b:45.5 occ:1.00 NE2 B:HIS1808 2.1 43.2 1.0 ND1 B:HIS1751 2.1 47.1 1.0 SG B:CYS1814 2.3 52.3 1.0 SG B:CYS1810 2.4 51.5 1.0 CE1 B:HIS1751 3.0 45.6 1.0 CD2 B:HIS1808 3.1 41.6 1.0 CE1 B:HIS1808 3.1 42.6 1.0 CG B:HIS1751 3.1 45.2 1.0 CB B:CYS1814 3.3 53.3 1.0 CB B:CYS1810 3.3 48.9 1.0 CA B:CYS1810 3.4 50.1 1.0 CB B:HIS1751 3.6 41.6 1.0 N B:CYS1810 4.0 48.5 1.0 NE2 B:HIS1751 4.1 47.5 1.0 CD2 B:HIS1751 4.2 46.9 1.0 ND1 B:HIS1808 4.2 42.6 1.0 CG B:HIS1808 4.2 43.1 1.0 O B:HOH3066 4.3 39.8 1.0 CA B:CYS1814 4.6 54.8 1.0 C B:CYS1810 4.6 52.7 1.0 C B:HIS1809 4.6 49.0 1.0 N B:ASN1811 4.6 52.6 1.0 CD1 B:LEU1819 4.6 47.4 1.0 O B:HIS1809 4.7 50.8 1.0

H.Yamaguchi, M.Matsushita, A.C.Nairn, J.Kuriyan. Crystal Structure of the Atypical Protein Kinase Domain of A Trp Channel with Phosphotransferase Activity. Mol.Cell V. 7 1047 2001.
ISSN: ISSN 1097-2765
PubMed: 11389851
DOI: 10.1016/S1097-2765(01)00256-8