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Zinc in PDB 1hqm: Crystal Structure of Thermus Aquaticus Core Rna Polymerase-Includes Complete Structure with Side-Chains (Except For Disordered Regions)- Further Refined From Original Deposition-Contains Additional Sequence Information

Enzymatic activity of Crystal Structure of Thermus Aquaticus Core Rna Polymerase-Includes Complete Structure with Side-Chains (Except For Disordered Regions)- Further Refined From Original Deposition-Contains Additional Sequence Information

All present enzymatic activity of Crystal Structure of Thermus Aquaticus Core Rna Polymerase-Includes Complete Structure with Side-Chains (Except For Disordered Regions)- Further Refined From Original Deposition-Contains Additional Sequence Information:
2.7.7.6;

Protein crystallography data

The structure of Crystal Structure of Thermus Aquaticus Core Rna Polymerase-Includes Complete Structure with Side-Chains (Except For Disordered Regions)- Further Refined From Original Deposition-Contains Additional Sequence Information, PDB code: 1hqm was solved by L.Minakhin, S.Bhagat, A.Brunning, E.A.Campbell, S.A.Darst, R.H.Ebright, K.Severinov, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 8.00 / 3.30
Space group P 41 21 2
Cell size a, b, c (Å), α, β, γ (°) 200.760, 200.760, 292.938, 90.00, 90.00, 90.00
R / Rfree (%) 30 / 36

Other elements in 1hqm:

The structure of Crystal Structure of Thermus Aquaticus Core Rna Polymerase-Includes Complete Structure with Side-Chains (Except For Disordered Regions)- Further Refined From Original Deposition-Contains Additional Sequence Information also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Thermus Aquaticus Core Rna Polymerase-Includes Complete Structure with Side-Chains (Except For Disordered Regions)- Further Refined From Original Deposition-Contains Additional Sequence Information (pdb code 1hqm). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Thermus Aquaticus Core Rna Polymerase-Includes Complete Structure with Side-Chains (Except For Disordered Regions)- Further Refined From Original Deposition-Contains Additional Sequence Information, PDB code: 1hqm:

Zinc binding site 1 out of 1 in 1hqm

Go back to Zinc Binding Sites List in 1hqm
Zinc binding site 1 out of 1 in the Crystal Structure of Thermus Aquaticus Core Rna Polymerase-Includes Complete Structure with Side-Chains (Except For Disordered Regions)- Further Refined From Original Deposition-Contains Additional Sequence Information


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Thermus Aquaticus Core Rna Polymerase-Includes Complete Structure with Side-Chains (Except For Disordered Regions)- Further Refined From Original Deposition-Contains Additional Sequence Information within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn2002

b:84.9
occ:1.00
SG D:CYS1195 1.9 56.4 1.0
SG D:CYS1202 2.1 0.1 1.0
SG D:CYS1205 2.6 71.4 1.0
CB D:CYS1202 3.0 0.1 1.0
SG D:CYS1113 3.1 63.1 1.0
CB D:CYS1195 3.6 60.0 1.0
CB D:CYS1205 3.9 74.1 1.0
N D:CYS1113 4.3 91.2 1.0
CB D:CYS1113 4.3 64.2 1.0
CA D:CYS1202 4.5 70.7 1.0
CA D:CYS1195 4.6 0.8 1.0
N D:GLN1203 4.6 0.7 1.0
O D:LYS1204 4.7 49.2 1.0
CA D:CYS1113 4.9 91.2 1.0
C D:LYS1204 5.0 49.2 1.0

Reference:

L.Minakhin, S.Bhagat, A.Brunning, E.A.Campbell, S.A.Darst, R.H.Ebright, K.Severinov. Bacterial Rna Polymerase Subunit Omega and Eukaryotic Rna Polymerase Subunit RPB6 Are Sequence, Structural, and Functional Homologs and Promote Rna Polymerase Assembly. Proc.Natl.Acad.Sci.Usa V. 98 892 2001.
ISSN: ISSN 0027-8424
PubMed: 11158566
DOI: 10.1073/PNAS.98.3.892
Page generated: Wed Dec 16 02:51:42 2020

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