Atomistry » Zinc » PDB 1hlk-1hxr » 1hp7
Atomistry »
  Zinc »
    PDB 1hlk-1hxr »
      1hp7 »

Zinc in PDB 1hp7: A 2.1 Angstrom Structure of An Uncleaved Alpha-1-Antitrypsin Shows Variability of the Reactive Center and Other Loops

Protein crystallography data

The structure of A 2.1 Angstrom Structure of An Uncleaved Alpha-1-Antitrypsin Shows Variability of the Reactive Center and Other Loops, PDB code: 1hp7 was solved by S.-J.Kim, J.-R.Woo, E.J.Seo, M.-H.Yu, S.-E.Ryu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 99.00 / 2.10
Space group P 32 1 2
Cell size a, b, c (Å), α, β, γ (°) 77.570, 77.570, 124.290, 90.00, 90.00, 120.00
R / Rfree (%) 21.9 / 27.3

Zinc Binding Sites:

The binding sites of Zinc atom in the A 2.1 Angstrom Structure of An Uncleaved Alpha-1-Antitrypsin Shows Variability of the Reactive Center and Other Loops (pdb code 1hp7). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 5 binding sites of Zinc where determined in the A 2.1 Angstrom Structure of An Uncleaved Alpha-1-Antitrypsin Shows Variability of the Reactive Center and Other Loops, PDB code: 1hp7:
Jump to Zinc binding site number: 1; 2; 3; 4; 5;

Zinc binding site 1 out of 5 in 1hp7

Go back to Zinc Binding Sites List in 1hp7
Zinc binding site 1 out of 5 in the A 2.1 Angstrom Structure of An Uncleaved Alpha-1-Antitrypsin Shows Variability of the Reactive Center and Other Loops


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of A 2.1 Angstrom Structure of An Uncleaved Alpha-1-Antitrypsin Shows Variability of the Reactive Center and Other Loops within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn401

b:36.7
occ:1.00
O A:HOH486 2.0 37.6 1.0
OE1 A:GLU89 2.0 48.6 1.0
NE2 A:HIS73 2.1 27.9 1.0
NE2 A:HIS93 2.1 29.2 1.0
CD A:GLU89 2.7 47.2 1.0
OE2 A:GLU89 2.8 50.0 1.0
CE1 A:HIS73 2.9 26.1 1.0
CE1 A:HIS93 3.0 29.9 1.0
CD2 A:HIS93 3.1 29.4 1.0
CD2 A:HIS73 3.2 26.1 1.0
CG A:GLU89 4.0 46.0 1.0
ND1 A:HIS93 4.1 29.3 1.0
ND1 A:HIS73 4.1 28.2 1.0
CG A:HIS93 4.2 28.9 1.0
CG A:HIS73 4.2 28.3 1.0
CB A:GLU89 4.7 43.1 1.0
CD1 A:LEU77 4.7 30.0 1.0

Zinc binding site 2 out of 5 in 1hp7

Go back to Zinc Binding Sites List in 1hp7
Zinc binding site 2 out of 5 in the A 2.1 Angstrom Structure of An Uncleaved Alpha-1-Antitrypsin Shows Variability of the Reactive Center and Other Loops


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of A 2.1 Angstrom Structure of An Uncleaved Alpha-1-Antitrypsin Shows Variability of the Reactive Center and Other Loops within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn402

b:36.1
occ:1.00
OE2 A:GLU151 1.9 26.9 1.0
OE2 A:GLU175 2.2 44.9 1.0
OE1 A:GLU175 2.6 45.6 1.0
CD A:GLU175 2.7 44.1 1.0
CD A:GLU151 2.9 28.3 1.0
CG A:GLU151 3.6 30.3 1.0
OE1 A:GLU151 3.7 27.2 1.0
O A:HOH510 4.1 42.1 1.0
CG A:GLU175 4.2 45.4 1.0
NZ A:LYS154 4.3 39.6 1.0
OG1 A:THR150 5.0 43.0 1.0
CB A:GLU151 5.0 32.3 1.0

Zinc binding site 3 out of 5 in 1hp7

Go back to Zinc Binding Sites List in 1hp7
Zinc binding site 3 out of 5 in the A 2.1 Angstrom Structure of An Uncleaved Alpha-1-Antitrypsin Shows Variability of the Reactive Center and Other Loops


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of A 2.1 Angstrom Structure of An Uncleaved Alpha-1-Antitrypsin Shows Variability of the Reactive Center and Other Loops within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn403

b:38.2
occ:1.00
ND1 A:HIS262 2.1 28.4 1.0
O A:HOH438 2.3 33.0 1.0
CE1 A:HIS262 3.0 28.2 1.0
CG A:HIS262 3.1 26.2 1.0
CB A:HIS262 3.5 28.6 1.0
CA A:HIS262 3.6 28.3 1.0
OE1 A:GLU266 3.8 47.4 1.0
NE2 A:HIS262 4.1 28.1 1.0
CD2 A:HIS262 4.2 28.7 1.0
CG A:GLU266 4.4 42.4 1.0
O A:HIS262 4.4 30.5 1.0
C A:HIS262 4.5 29.1 1.0
CD A:GLU266 4.5 45.0 1.0
N A:HIS262 4.7 28.4 1.0
CB A:ASN265 5.0 34.1 1.0

Zinc binding site 4 out of 5 in 1hp7

Go back to Zinc Binding Sites List in 1hp7
Zinc binding site 4 out of 5 in the A 2.1 Angstrom Structure of An Uncleaved Alpha-1-Antitrypsin Shows Variability of the Reactive Center and Other Loops


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of A 2.1 Angstrom Structure of An Uncleaved Alpha-1-Antitrypsin Shows Variability of the Reactive Center and Other Loops within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn404

b:42.8
occ:1.00
OG A:SER285 2.0 27.3 1.0
OE1 A:GLU363 2.2 39.0 1.0
NE2 A:HIS287 2.5 28.2 1.0
CD A:GLU363 2.9 39.4 1.0
OE2 A:GLU363 2.9 41.0 1.0
CB A:SER285 3.2 26.5 1.0
CD2 A:HIS287 3.2 26.5 1.0
CE1 A:HIS287 3.6 27.8 1.0
CG A:GLU363 4.3 36.8 1.0
CA A:SER285 4.4 26.7 1.0
CG A:HIS287 4.4 27.9 1.0
C A:SER285 4.5 24.9 1.0
ND1 A:HIS287 4.6 30.8 1.0
O A:SER285 4.7 22.6 1.0
CB A:GLU363 4.9 33.9 1.0

Zinc binding site 5 out of 5 in 1hp7

Go back to Zinc Binding Sites List in 1hp7
Zinc binding site 5 out of 5 in the A 2.1 Angstrom Structure of An Uncleaved Alpha-1-Antitrypsin Shows Variability of the Reactive Center and Other Loops


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of A 2.1 Angstrom Structure of An Uncleaved Alpha-1-Antitrypsin Shows Variability of the Reactive Center and Other Loops within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn405

b:39.6
occ:1.00
NE2 A:HIS101 1.9 40.4 1.0
NE2 A:HIS139 2.1 37.8 1.0
CD2 A:HIS101 2.8 38.9 1.0
CE1 A:HIS101 2.9 40.1 1.0
CD2 A:HIS139 3.0 36.6 1.0
CE1 A:HIS139 3.1 36.4 1.0
O A:LYS136 3.7 33.3 1.0
CG A:HIS101 4.0 39.8 1.0
ND1 A:HIS101 4.0 40.8 1.0
ND1 A:HIS139 4.2 36.3 1.0
CG A:HIS139 4.2 35.8 1.0
O A:LEU137 4.4 32.0 1.0
C A:LYS136 4.9 34.2 1.0

Reference:

S.Kim, J.Woo, E.J.Seo, M.Yu, S.Ryu. A 2.1 A Resolution Structure of An Uncleaved Alpha(1)-Antitrypsin Shows Variability of the Reactive Center and Other Loops. J.Mol.Biol. V. 306 109 2001.
ISSN: ISSN 0022-2836
PubMed: 11178897
DOI: 10.1006/JMBI.2000.4357
Page generated: Wed Dec 16 02:51:25 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy