Zinc in PDB 1g2f: Structure of A CYS2HIS2 Zinc Finger/Tata Box Complex (Tatazf;Clone #6)
Protein crystallography data
The structure of Structure of A CYS2HIS2 Zinc Finger/Tata Box Complex (Tatazf;Clone #6), PDB code: 1g2f
was solved by
S.A.Wolfe,
R.A.Grant,
M.Elrod-Erickson,
C.O.Pabo,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
20.00 /
2.00
|
Space group
|
P 64
|
Cell size a, b, c (Å), α, β, γ (°)
|
104.800,
104.800,
104.200,
90.00,
90.00,
120.00
|
R / Rfree (%)
|
23.3 /
26.3
|
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of A CYS2HIS2 Zinc Finger/Tata Box Complex (Tatazf;Clone #6)
(pdb code 1g2f). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 6 binding sites of Zinc where determined in the
Structure of A CYS2HIS2 Zinc Finger/Tata Box Complex (Tatazf;Clone #6), PDB code: 1g2f:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
Zinc binding site 1 out
of 6 in 1g2f
Go back to
Zinc Binding Sites List in 1g2f
Zinc binding site 1 out
of 6 in the Structure of A CYS2HIS2 Zinc Finger/Tata Box Complex (Tatazf;Clone #6)
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Structure of A CYS2HIS2 Zinc Finger/Tata Box Complex (Tatazf;Clone #6) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn301
b:50.7
occ:1.00
|
NE2
|
C:HIS129
|
1.9
|
37.9
|
1.0
|
NE2
|
C:HIS125
|
2.1
|
40.2
|
1.0
|
SG
|
C:CYS107
|
2.3
|
46.6
|
1.0
|
SG
|
C:CYS112
|
2.5
|
57.9
|
1.0
|
CD2
|
C:HIS129
|
2.8
|
42.6
|
1.0
|
CB
|
C:CYS112
|
2.9
|
62.6
|
1.0
|
CE1
|
C:HIS129
|
3.0
|
42.6
|
1.0
|
CE1
|
C:HIS125
|
3.1
|
38.8
|
1.0
|
CD2
|
C:HIS125
|
3.1
|
41.6
|
1.0
|
CB
|
C:CYS107
|
3.4
|
43.5
|
1.0
|
CG
|
C:HIS129
|
4.0
|
44.4
|
1.0
|
ND1
|
C:HIS129
|
4.1
|
44.4
|
1.0
|
ND1
|
C:HIS125
|
4.1
|
39.7
|
1.0
|
CG
|
C:HIS125
|
4.2
|
38.8
|
1.0
|
CB
|
C:VAL109
|
4.4
|
56.8
|
1.0
|
CA
|
C:CYS112
|
4.4
|
64.7
|
1.0
|
CG2
|
C:VAL109
|
4.5
|
54.8
|
1.0
|
N
|
C:ASP113
|
4.7
|
66.4
|
1.0
|
CA
|
C:CYS107
|
4.8
|
46.5
|
1.0
|
C
|
C:CYS112
|
4.9
|
65.3
|
1.0
|
|
Zinc binding site 2 out
of 6 in 1g2f
Go back to
Zinc Binding Sites List in 1g2f
Zinc binding site 2 out
of 6 in the Structure of A CYS2HIS2 Zinc Finger/Tata Box Complex (Tatazf;Clone #6)
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Structure of A CYS2HIS2 Zinc Finger/Tata Box Complex (Tatazf;Clone #6) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn302
b:45.5
occ:1.00
|
NE2
|
C:HIS157
|
2.0
|
44.7
|
1.0
|
NE2
|
C:HIS153
|
2.2
|
43.1
|
1.0
|
SG
|
C:CYS137
|
2.3
|
38.2
|
1.0
|
SG
|
C:CYS140
|
2.4
|
44.6
|
1.0
|
CD2
|
C:HIS157
|
2.9
|
43.1
|
1.0
|
CB
|
C:CYS137
|
3.1
|
36.4
|
1.0
|
CE1
|
C:HIS157
|
3.1
|
44.8
|
1.0
|
CD2
|
C:HIS153
|
3.1
|
39.7
|
1.0
|
CE1
|
C:HIS153
|
3.2
|
40.3
|
1.0
|
CB
|
C:CYS140
|
3.5
|
42.8
|
1.0
|
N
|
C:CYS140
|
3.5
|
40.8
|
1.0
|
CA
|
C:CYS140
|
4.0
|
40.9
|
1.0
|
CG
|
C:HIS157
|
4.1
|
45.2
|
1.0
|
ND1
|
C:HIS157
|
4.1
|
44.0
|
1.0
|
CB
|
C:ILE139
|
4.1
|
41.9
|
1.0
|
ND1
|
C:HIS153
|
4.2
|
37.7
|
1.0
|
CG
|
C:HIS153
|
4.3
|
36.3
|
1.0
|
CA
|
C:CYS137
|
4.5
|
38.4
|
1.0
|
C
|
C:ILE139
|
4.6
|
41.6
|
1.0
|
N
|
C:ILE139
|
4.7
|
43.2
|
1.0
|
CA
|
C:ILE139
|
4.7
|
41.7
|
1.0
|
C
|
C:CYS140
|
4.7
|
42.5
|
1.0
|
N
|
C:MET141
|
4.8
|
43.7
|
1.0
|
C
|
C:CYS137
|
4.8
|
38.6
|
1.0
|
CG1
|
C:ILE139
|
4.9
|
39.4
|
1.0
|
CG2
|
C:ILE139
|
4.9
|
37.7
|
1.0
|
CB
|
C:ARG142
|
4.9
|
39.3
|
1.0
|
N
|
C:ARG142
|
5.0
|
42.5
|
1.0
|
O
|
C:CYS137
|
5.0
|
38.3
|
1.0
|
|
Zinc binding site 3 out
of 6 in 1g2f
Go back to
Zinc Binding Sites List in 1g2f
Zinc binding site 3 out
of 6 in the Structure of A CYS2HIS2 Zinc Finger/Tata Box Complex (Tatazf;Clone #6)
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Structure of A CYS2HIS2 Zinc Finger/Tata Box Complex (Tatazf;Clone #6) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn303
b:47.9
occ:1.00
|
NE2
|
C:HIS185
|
2.1
|
47.1
|
1.0
|
NE2
|
C:HIS181
|
2.1
|
35.2
|
1.0
|
SG
|
C:CYS168
|
2.2
|
44.0
|
1.0
|
SG
|
C:CYS165
|
2.5
|
43.5
|
1.0
|
CE1
|
C:HIS185
|
2.9
|
46.5
|
1.0
|
CD2
|
C:HIS181
|
3.0
|
35.7
|
1.0
|
CD2
|
C:HIS185
|
3.1
|
49.0
|
1.0
|
CE1
|
C:HIS181
|
3.2
|
39.4
|
1.0
|
CB
|
C:CYS168
|
3.3
|
45.2
|
1.0
|
CB
|
C:CYS165
|
3.3
|
46.8
|
1.0
|
N
|
C:CYS168
|
3.6
|
47.5
|
1.0
|
CA
|
C:CYS168
|
4.0
|
46.1
|
1.0
|
ND1
|
C:HIS185
|
4.1
|
46.8
|
1.0
|
CG
|
C:HIS181
|
4.2
|
35.9
|
1.0
|
CG
|
C:HIS185
|
4.2
|
46.0
|
1.0
|
ND1
|
C:HIS181
|
4.2
|
38.9
|
1.0
|
CB
|
C:ILE167
|
4.5
|
46.5
|
1.0
|
C
|
C:ILE167
|
4.6
|
49.1
|
1.0
|
C
|
C:CYS168
|
4.7
|
48.5
|
1.0
|
CA
|
C:CYS165
|
4.8
|
47.8
|
1.0
|
N
|
C:GLY169
|
4.8
|
50.3
|
1.0
|
CA
|
C:ILE167
|
4.9
|
49.4
|
1.0
|
CB
|
C:ARG170
|
5.0
|
56.3
|
1.0
|
CA
|
C:THR182
|
5.0
|
42.1
|
1.0
|
|
Zinc binding site 4 out
of 6 in 1g2f
Go back to
Zinc Binding Sites List in 1g2f
Zinc binding site 4 out
of 6 in the Structure of A CYS2HIS2 Zinc Finger/Tata Box Complex (Tatazf;Clone #6)
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Structure of A CYS2HIS2 Zinc Finger/Tata Box Complex (Tatazf;Clone #6) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Zn304
b:53.6
occ:1.00
|
NE2
|
F:HIS229
|
2.1
|
37.4
|
1.0
|
NE2
|
F:HIS225
|
2.1
|
53.5
|
1.0
|
SG
|
F:CYS207
|
2.2
|
46.9
|
1.0
|
SG
|
F:CYS212
|
2.3
|
63.1
|
1.0
|
CE1
|
F:HIS225
|
2.9
|
52.3
|
1.0
|
CB
|
F:CYS212
|
3.0
|
69.9
|
1.0
|
CD2
|
F:HIS229
|
3.1
|
39.1
|
1.0
|
CE1
|
F:HIS229
|
3.1
|
40.8
|
1.0
|
CD2
|
F:HIS225
|
3.2
|
51.3
|
1.0
|
CB
|
F:CYS207
|
3.3
|
47.9
|
1.0
|
ND1
|
F:HIS225
|
4.1
|
50.3
|
1.0
|
CG
|
F:HIS225
|
4.2
|
47.6
|
1.0
|
ND1
|
F:HIS229
|
4.2
|
39.8
|
1.0
|
CG
|
F:HIS229
|
4.2
|
37.6
|
1.0
|
CB
|
F:ARG214
|
4.5
|
67.2
|
1.0
|
CB
|
F:VAL209
|
4.5
|
52.3
|
1.0
|
CA
|
F:CYS212
|
4.5
|
71.8
|
1.0
|
CG2
|
F:VAL209
|
4.6
|
51.4
|
1.0
|
CA
|
F:CYS207
|
4.7
|
51.0
|
1.0
|
N
|
F:ARG214
|
4.9
|
74.8
|
1.0
|
N
|
F:ASP213
|
4.9
|
75.7
|
1.0
|
|
Zinc binding site 5 out
of 6 in 1g2f
Go back to
Zinc Binding Sites List in 1g2f
Zinc binding site 5 out
of 6 in the Structure of A CYS2HIS2 Zinc Finger/Tata Box Complex (Tatazf;Clone #6)
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of Structure of A CYS2HIS2 Zinc Finger/Tata Box Complex (Tatazf;Clone #6) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Zn305
b:34.1
occ:1.00
|
NE2
|
F:HIS253
|
2.0
|
34.6
|
1.0
|
NE2
|
F:HIS257
|
2.1
|
33.3
|
1.0
|
SG
|
F:CYS240
|
2.3
|
44.3
|
1.0
|
SG
|
F:CYS237
|
2.3
|
34.0
|
1.0
|
CD2
|
F:HIS257
|
2.9
|
34.7
|
1.0
|
CD2
|
F:HIS253
|
3.0
|
32.9
|
1.0
|
CE1
|
F:HIS253
|
3.0
|
31.8
|
1.0
|
CE1
|
F:HIS257
|
3.2
|
33.2
|
1.0
|
CB
|
F:CYS237
|
3.2
|
31.7
|
1.0
|
CB
|
F:CYS240
|
3.4
|
37.1
|
1.0
|
N
|
F:CYS240
|
3.6
|
33.4
|
1.0
|
CA
|
F:CYS240
|
4.0
|
36.4
|
1.0
|
ND1
|
F:HIS253
|
4.1
|
28.8
|
1.0
|
CG
|
F:HIS257
|
4.1
|
31.6
|
1.0
|
CG
|
F:HIS253
|
4.1
|
31.9
|
1.0
|
CB
|
F:ILE239
|
4.2
|
36.0
|
1.0
|
ND1
|
F:HIS257
|
4.2
|
34.4
|
1.0
|
C
|
F:ILE239
|
4.6
|
33.0
|
1.0
|
CA
|
F:CYS237
|
4.6
|
33.1
|
1.0
|
C
|
F:CYS240
|
4.8
|
37.7
|
1.0
|
CA
|
F:ILE239
|
4.8
|
34.7
|
1.0
|
N
|
F:ILE239
|
4.9
|
33.8
|
1.0
|
CG2
|
F:ILE239
|
4.9
|
30.3
|
1.0
|
CB
|
F:ARG242
|
4.9
|
36.1
|
1.0
|
N
|
F:MET241
|
5.0
|
38.2
|
1.0
|
|
Zinc binding site 6 out
of 6 in 1g2f
Go back to
Zinc Binding Sites List in 1g2f
Zinc binding site 6 out
of 6 in the Structure of A CYS2HIS2 Zinc Finger/Tata Box Complex (Tatazf;Clone #6)
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of Structure of A CYS2HIS2 Zinc Finger/Tata Box Complex (Tatazf;Clone #6) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Zn306
b:28.9
occ:1.00
|
NE2
|
F:HIS285
|
2.1
|
39.1
|
1.0
|
NE2
|
F:HIS281
|
2.2
|
29.6
|
1.0
|
SG
|
F:CYS268
|
2.2
|
31.9
|
1.0
|
SG
|
F:CYS265
|
2.3
|
30.1
|
1.0
|
CD2
|
F:HIS281
|
3.0
|
26.7
|
1.0
|
CE1
|
F:HIS285
|
3.0
|
37.2
|
1.0
|
CD2
|
F:HIS285
|
3.1
|
36.9
|
1.0
|
CE1
|
F:HIS281
|
3.2
|
27.6
|
1.0
|
CB
|
F:CYS265
|
3.3
|
30.5
|
1.0
|
CB
|
F:CYS268
|
3.4
|
30.7
|
1.0
|
N
|
F:CYS268
|
3.7
|
36.3
|
1.0
|
ND1
|
F:HIS285
|
4.1
|
37.6
|
1.0
|
CA
|
F:CYS268
|
4.1
|
36.0
|
1.0
|
CG
|
F:HIS281
|
4.2
|
27.0
|
1.0
|
CG
|
F:HIS285
|
4.2
|
36.9
|
1.0
|
ND1
|
F:HIS281
|
4.3
|
31.5
|
1.0
|
CB
|
F:ILE267
|
4.5
|
35.0
|
1.0
|
C
|
F:ILE267
|
4.6
|
37.2
|
1.0
|
CA
|
F:CYS265
|
4.7
|
32.0
|
1.0
|
CA
|
F:THR282
|
4.8
|
40.0
|
1.0
|
CG2
|
F:THR282
|
4.8
|
35.2
|
1.0
|
CA
|
F:ILE267
|
4.9
|
35.5
|
1.0
|
C
|
F:CYS268
|
4.9
|
38.1
|
1.0
|
N
|
F:ILE267
|
4.9
|
37.0
|
1.0
|
CB
|
F:ARG270
|
5.0
|
40.5
|
1.0
|
O
|
F:HIS281
|
5.0
|
30.6
|
1.0
|
N
|
F:GLY269
|
5.0
|
37.2
|
1.0
|
C
|
F:CYS265
|
5.0
|
33.1
|
1.0
|
|
Reference:
S.A.Wolfe,
R.A.Grant,
M.Elrod-Erickson,
C.O.Pabo.
Beyond the "Recognition Code": Structures of Two CYS2HIS2 Zinc Finger/Tata Box Complexes. Structure V. 9 717 2001.
ISSN: ISSN 0969-2126
PubMed: 11587646
DOI: 10.1016/S0969-2126(01)00632-3
Page generated: Sun Oct 13 01:16:09 2024
|