Zinc in PDB 1fls: Solution Structure of the Catalytic Fragment of Human Collagenase-3 (Mmp-13) Complexed with A Hydroxamic Acid Inhibitor

The structure of Solution Structure of the Catalytic Fragment of Human Collagenase-3 (Mmp-13) Complexed with A Hydroxamic Acid Inhibitor also contains other interesting chemical elements:

Calcium

(Ca)

1 atom

The binding sites of Zinc atom in the Solution Structure of the Catalytic Fragment of Human Collagenase-3 (Mmp-13) Complexed with A Hydroxamic Acid Inhibitor (pdb code 1fls). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Solution Structure of the Catalytic Fragment of Human Collagenase-3 (Mmp-13) Complexed with A Hydroxamic Acid Inhibitor, PDB code: 1fls:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Solution Structure of the Catalytic Fragment of Human Collagenase-3 (Mmp-13) Complexed with A Hydroxamic Acid Inhibitor


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Solution Structure of the Catalytic Fragment of Human Collagenase-3 (Mmp-13) Complexed with A Hydroxamic Acid Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn166 b:0.2 occ:1.00 NE2 A:HIS119 2.1 0.2 1.0 O13 A:WAY169 2.1 0.7 1.0 NE2 A:HIS123 2.2 0.3 1.0 NE2 A:HIS129 2.2 0.3 1.0 O11 A:WAY169 2.3 0.6 1.0 H15 A:WAY169 2.4 1.1 1.0 CE1 A:HIS119 3.0 0.3 1.0 CE1 A:HIS123 3.0 0.4 1.0 N12 A:WAY169 3.0 0.6 1.0 CD2 A:HIS129 3.0 0.3 1.0 C10 A:WAY169 3.0 0.4 1.0 HE1 A:HIS119 3.1 0.3 1.0 HD2 A:HIS129 3.1 0.5 1.0 HE1 A:HIS123 3.2 0.5 1.0 CD2 A:HIS123 3.2 0.2 1.0 CE1 A:HIS129 3.2 0.3 1.0 CD2 A:HIS119 3.2 0.2 1.0 HD2 A:HIS123 3.5 0.3 1.0 HD2 A:HIS119 3.6 0.2 1.0 HE1 A:HIS129 3.6 0.4 1.0 H14 A:WAY169 3.9 0.9 1.0 ND1 A:HIS123 4.1 0.4 1.0 CG A:HIS129 4.2 0.2 1.0 ND1 A:HIS119 4.2 0.3 1.0 CG A:HIS123 4.2 0.3 1.0 ND1 A:HIS129 4.3 0.3 1.0 CG A:HIS119 4.3 0.2 1.0 C2 A:WAY169 4.5 0.3 1.0 HA A:PRO139 4.6 0.3 1.0 HD2 A:WAY169 4.6 0.3 1.0 HE1 A:MET137 4.7 1.1 1.0 HD1 A:WAY169 4.9 0.3 1.0 HD1 A:HIS123 5.0 0.5 1.0 HC1 A:WAY169 5.0 0.3 1.0

Zinc binding site 2 out of 2 in the Solution Structure of the Catalytic Fragment of Human Collagenase-3 (Mmp-13) Complexed with A Hydroxamic Acid Inhibitor


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Solution Structure of the Catalytic Fragment of Human Collagenase-3 (Mmp-13) Complexed with A Hydroxamic Acid Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn167 b:1.0 occ:1.00 ND1 A:HIS97 1.9 0.8 1.0 NE2 A:HIS84 2.1 0.5 1.0 HB2 A:HIS97 2.4 0.4 1.0 NE2 A:HIS69 2.5 1.5 1.0 HB3 A:HIS97 2.6 0.4 1.0 CB A:HIS97 2.7 0.3 1.0 CG A:HIS97 2.7 0.4 1.0 CD2 A:HIS69 2.9 1.0 1.0 CE1 A:HIS84 2.9 1.2 1.0 CE1 A:HIS69 3.0 1.8 1.0 HE1 A:HIS84 3.1 1.9 1.0 CE1 A:HIS97 3.1 0.9 1.0 HZ A:PHE75 3.2 0.8 1.0 CD2 A:HIS84 3.3 0.7 1.0 HD2 A:HIS69 3.3 1.4 1.0 HE1 A:HIS69 3.4 2.5 1.0 HE1 A:HIS97 3.5 1.2 1.0 CG A:HIS69 3.6 0.9 1.0 ND1 A:HIS69 3.6 1.4 1.0 HD2 A:HIS84 3.6 1.6 1.0 CD2 A:HIS97 3.9 0.6 1.0 NE2 A:HIS97 4.1 0.6 1.0 HE2 A:PHE75 4.1 1.1 1.0 CZ A:PHE75 4.1 0.7 1.0 ND1 A:HIS84 4.2 1.3 1.0 CA A:HIS97 4.2 0.3 1.0 HD1 A:HIS69 4.3 1.8 1.0 CG A:HIS84 4.3 0.4 1.0 CE2 A:PHE75 4.5 0.8 1.0 HB2 A:HIS69 4.7 2.3 1.0 CB A:HIS69 4.7 1.5 1.0 HA A:HIS97 4.7 0.3 1.0 H A:HIS97 4.8 0.3 1.0 N A:HIS97 4.8 0.2 1.0 HD2 A:HIS97 4.9 0.9 1.0 C A:HIS97 4.9 0.3 1.0 HB3 A:HIS69 4.9 2.1 1.0 HE1 A:PHE86 5.0 0.7 1.0

F.J.Moy, P.K.Chanda, J.M.Chen, S.Cosmi, W.Edris, J.I.Levin, R.Powers. High-Resolution Solution Structure of the Catalytic Fragment of Human Collagenase-3 (Mmp-13) Complexed with A Hydroxamic Acid Inhibitor. J.Mol.Biol. V. 302 671 2000.
ISSN: ISSN 0022-2836
PubMed: 10986126
DOI: 10.1006/JMBI.2000.4082