Zinc in PDB 1f4t: Thermophilic P450: CYP119 From Sulfolobus Solfactaricus with 4- Phenylimidazole Bound

The structure of Thermophilic P450: CYP119 From Sulfolobus Solfactaricus with 4- Phenylimidazole Bound, PDB code: 1f4t was solved by J.K.Yano, L.S.Koo, D.J.Schuller, H.Li, P.R.Ortiz De Montellano, T.L.Poulos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.40 / 1.93
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	76.958, 114.600, 185.201, 90.00, 90.00, 90.00
R / Rfree (%)	22.5 / 27.4

The structure of Thermophilic P450: CYP119 From Sulfolobus Solfactaricus with 4- Phenylimidazole Bound also contains other interesting chemical elements:

Iron

(Fe)

2 atoms

The binding sites of Zinc atom in the Thermophilic P450: CYP119 From Sulfolobus Solfactaricus with 4- Phenylimidazole Bound (pdb code 1f4t). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Thermophilic P450: CYP119 From Sulfolobus Solfactaricus with 4- Phenylimidazole Bound, PDB code: 1f4t:

Zinc binding site 1 out of 1 in the Thermophilic P450: CYP119 From Sulfolobus Solfactaricus with 4- Phenylimidazole Bound


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Thermophilic P450: CYP119 From Sulfolobus Solfactaricus with 4- Phenylimidazole Bound within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn369 b:37.0 occ:1.00 OE1 B:GLU139 1.9 38.2 1.0 NE2 A:HIS178 2.0 37.2 1.0 OE1 A:GLU139 2.0 38.3 1.0 NE2 B:HIS178 2.0 37.2 1.0 CE1 A:HIS178 2.6 37.6 1.0 CD2 B:HIS178 2.8 36.7 1.0 CD A:GLU139 2.8 40.0 1.0 CD B:GLU139 2.8 40.5 1.0 OE2 A:GLU139 3.0 39.4 1.0 CE1 B:HIS178 3.1 36.7 1.0 OE2 B:GLU139 3.2 40.3 1.0 CD2 A:HIS178 3.2 38.7 1.0 ND1 A:HIS178 3.9 39.1 1.0 O A:HOH565 3.9 36.1 1.0 CG B:HIS178 4.0 37.5 1.0 ND1 B:HIS178 4.1 36.6 1.0 CG A:HIS178 4.1 39.3 1.0 CG B:GLU139 4.2 41.2 1.0 CG A:GLU139 4.2 39.8 1.0 O B:HOH414 4.6 40.2 1.0 CB B:PRO137 4.9 39.0 1.0 CG B:PRO137 4.9 39.6 1.0

J.K.Yano, L.S.Koo, D.J.Schuller, H.Li, P.R.Ortiz De Montellano, T.L.Poulos. Crystal Structure of A Thermophilic Cytochrome P450 From the Archaeon Sulfolobus Solfataricus. J.Biol.Chem. V. 275 31086 2000.
ISSN: ISSN 0021-9258
PubMed: 10859321
DOI: 10.1074/JBC.M004281200