Zinc in PDB 1e31: Survivin Dimer H. Sapiens

The structure of Survivin Dimer H. Sapiens, PDB code: 1e31 was solved by L.Chantalat, D.A.Skoufias, R.L.Margolis, O.Dideberg, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.76 / 2.71
Space group	I 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	82.220, 71.050, 89.450, 90.00, 96.12, 90.00
R / Rfree (%)	23.5 / 27

The structure of Survivin Dimer H. Sapiens also contains other interesting chemical elements:

Cobalt

(Co)

1 atom

The binding sites of Zinc atom in the Survivin Dimer H. Sapiens (pdb code 1e31). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Survivin Dimer H. Sapiens, PDB code: 1e31:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Survivin Dimer H. Sapiens


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Survivin Dimer H. Sapiens within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn801 b:67.0 occ:1.00 NE2 A:HIS77 2.3 73.4 1.0 SG A:CYS57 2.3 58.8 1.0 SG A:CYS60 2.3 69.0 1.0 SG A:CYS84 2.4 76.9 1.0 CE1 A:HIS77 2.9 72.0 1.0 CB A:CYS57 3.1 59.7 1.0 CB A:CYS84 3.4 77.4 1.0 CB A:CYS60 3.4 66.3 1.0 CD2 A:HIS77 3.5 73.1 1.0 N A:CYS60 3.7 60.4 1.0 ND1 A:HIS77 4.1 72.1 1.0 CA A:CYS60 4.2 60.0 1.0 CG A:HIS77 4.4 73.7 1.0 OG A:SER81 4.5 73.8 1.0 CB A:PHE59 4.5 54.4 1.0 CA A:CYS57 4.6 56.9 1.0 CA A:CYS84 4.8 76.6 1.0 C A:PHE59 4.8 55.4 1.0 CB A:SER81 4.9 76.9 1.0 N A:PHE61 4.9 65.8 1.0 C A:CYS60 4.9 60.9 1.0

Zinc binding site 2 out of 2 in the Survivin Dimer H. Sapiens


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Survivin Dimer H. Sapiens within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn801 b:67.2 occ:1.00 SG B:CYS57 2.2 65.8 1.0 NE2 B:HIS77 2.3 72.5 1.0 SG B:CYS60 2.4 73.9 1.0 SG B:CYS84 2.4 68.9 1.0 CE1 B:HIS77 2.7 70.8 1.0 CB B:CYS57 3.1 67.6 1.0 CB B:CYS84 3.2 70.9 1.0 CB B:CYS60 3.3 73.5 1.0 CD2 B:HIS77 3.5 69.5 1.0 N B:CYS60 3.7 59.6 1.0 ND1 B:HIS77 4.0 68.5 1.0 CA B:CYS60 4.1 59.8 1.0 CG B:HIS77 4.4 71.5 1.0 CA B:CYS84 4.5 73.0 1.0 OG B:SER81 4.5 72.9 1.0 CA B:CYS57 4.6 61.1 1.0 CB B:PHE59 4.6 57.1 1.0 C B:PHE59 4.7 59.8 1.0 N B:PHE61 4.9 73.4 1.0 C B:CYS60 4.9 60.7 1.0 CB B:SER81 4.9 71.8 1.0 N B:PHE59 5.0 58.3 1.0 CA B:PHE59 5.0 58.8 1.0

L.Chantalat, D.A.Skoufias, J.P.Kleman, B.Jung, O.Dideberg, R.L.Margolis. Crystal Structure of Human Survivin Reveals A Bow Tie-Shaped Dimer with Two Unusual Alpha-Helical Extensions Mol.Cell V. 6 183 2000.
ISSN: ISSN 1097-2765
PubMed: 10949039
DOI: 10.1016/S1097-2765(00)00019-8