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Zinc in PDB 1bc8: Structures of Sap-1 Bound to Dna Sequences From the E74 and C-Fos Promoters Provide Insights Into How Ets Proteins Discriminate Between Related Dna Targets

Protein crystallography data

The structure of Structures of Sap-1 Bound to Dna Sequences From the E74 and C-Fos Promoters Provide Insights Into How Ets Proteins Discriminate Between Related Dna Targets, PDB code: 1bc8 was solved by Y.Mo, B.Vaessen, K.Johnston, R.Marmorstein, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 28.90 / 1.93
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 31.590, 55.670, 44.230, 90.00, 107.16, 90.00
R / Rfree (%) 22 / 27.7

Zinc Binding Sites:

The binding sites of Zinc atom in the Structures of Sap-1 Bound to Dna Sequences From the E74 and C-Fos Promoters Provide Insights Into How Ets Proteins Discriminate Between Related Dna Targets (pdb code 1bc8). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structures of Sap-1 Bound to Dna Sequences From the E74 and C-Fos Promoters Provide Insights Into How Ets Proteins Discriminate Between Related Dna Targets, PDB code: 1bc8:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 1bc8

Go back to Zinc Binding Sites List in 1bc8
Zinc binding site 1 out of 2 in the Structures of Sap-1 Bound to Dna Sequences From the E74 and C-Fos Promoters Provide Insights Into How Ets Proteins Discriminate Between Related Dna Targets


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structures of Sap-1 Bound to Dna Sequences From the E74 and C-Fos Promoters Provide Insights Into How Ets Proteins Discriminate Between Related Dna Targets within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn2

b:26.3
occ:1.00
O B:HOH54 2.1 35.4 1.0
N7 B:DG18 2.2 16.6 1.0
O B:HOH135 2.2 20.9 1.0
O B:HOH136 2.4 16.8 1.0
O B:HOH137 2.4 18.9 1.0
O B:HOH82 2.6 33.6 1.0
C8 B:DG18 3.1 16.4 1.0
C5 B:DG18 3.3 14.3 1.0
O6 B:DG18 3.6 13.5 1.0
C6 B:DG18 3.8 16.1 1.0
O6 B:DG19 4.2 16.5 1.0
O B:HOH83 4.2 15.7 1.0
N9 B:DG18 4.3 16.5 1.0
O B:HOH81 4.4 46.9 1.0
O B:HOH80 4.4 29.2 1.0
C4 B:DG18 4.4 13.9 1.0
C6 B:DC17 4.6 14.8 1.0
C5 B:DC17 4.7 17.1 1.0
C2' B:DC17 4.8 15.2 1.0
N7 B:DG19 4.9 18.8 1.0
O A:HOH53 4.9 34.8 1.0

Zinc binding site 2 out of 2 in 1bc8

Go back to Zinc Binding Sites List in 1bc8
Zinc binding site 2 out of 2 in the Structures of Sap-1 Bound to Dna Sequences From the E74 and C-Fos Promoters Provide Insights Into How Ets Proteins Discriminate Between Related Dna Targets


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structures of Sap-1 Bound to Dna Sequences From the E74 and C-Fos Promoters Provide Insights Into How Ets Proteins Discriminate Between Related Dna Targets within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn94

b:15.7
occ:1.00
O C:HOH118 2.0 14.6 1.0
OE2 C:GLU89 2.0 19.3 1.0
CD C:GLU89 2.8 19.3 1.0
OE1 C:GLU89 3.1 18.8 1.0
O C:ASN92 4.2 33.5 1.0
O C:HOH115 4.2 19.5 1.0
CG C:GLU89 4.2 19.4 1.0
CB C:ASN92 4.3 30.5 1.0
ND2 C:ASN92 4.4 31.2 1.0
CG C:ASN92 4.6 31.1 1.0
CA C:GLU89 4.9 20.1 1.0
O C:GLU89 5.0 19.6 1.0

Reference:

Y.Mo, B.Vaessen, K.Johnston, R.Marmorstein. Structures of Sap-1 Bound to Dna Targets From the E74 and C-Fos Promoters: Insights Into Dna Sequence Discrimination By Ets Proteins. Mol.Cell V. 2 201 1998.
ISSN: ISSN 1097-2765
PubMed: 9734357
DOI: 10.1016/S1097-2765(00)80130-6
Page generated: Fri Sep 25 21:03:16 2020
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