Zinc in PDB 1aln: Crystal Structure of Cytidine Deaminase Complexed with 3-Deazacytidine

All present enzymatic activity of Crystal Structure of Cytidine Deaminase Complexed with 3-Deazacytidine:
3.5.4.5;

The structure of Crystal Structure of Cytidine Deaminase Complexed with 3-Deazacytidine, PDB code: 1aln was solved by S.Xiang, C.W.Carter, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	7.00 / 2.30
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	120.300, 120.300, 78.400, 90.00, 90.00, 120.00
R / Rfree (%)	19 / n/a

The binding sites of Zinc atom in the Crystal Structure of Cytidine Deaminase Complexed with 3-Deazacytidine (pdb code 1aln). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Cytidine Deaminase Complexed with 3-Deazacytidine, PDB code: 1aln:

Zinc binding site 1 out of 1 in the Crystal Structure of Cytidine Deaminase Complexed with 3-Deazacytidine


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Cytidine Deaminase Complexed with 3-Deazacytidine within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn296 b:22.5 occ:1.00 O A:HOH700 2.1 19.4 0.9 SG A:CYS132 2.2 16.4 1.0 ND1 A:HIS102 2.4 23.0 1.0 SG A:CYS129 2.4 23.8 1.0 CG A:HIS102 2.9 22.4 1.0 CE1 A:HIS102 3.1 23.6 1.0 CB A:CYS132 3.3 20.2 1.0 CB A:HIS102 3.4 16.9 1.0 CB A:CYS129 3.4 14.2 1.0 N A:CYS129 3.8 19.8 1.0 OE2 A:GLU104 3.8 25.7 1.0 CD2 A:HIS102 3.9 23.4 1.0 NE2 A:HIS102 3.9 22.4 1.0 N A:CYS132 4.0 15.9 1.0 OE1 A:GLU104 4.1 24.6 1.0 CA A:CYS129 4.1 17.9 1.0 ND1 A:HIS131 4.1 21.1 1.0 CD A:GLU104 4.2 23.0 1.0 CA A:CYS132 4.2 18.5 1.0 C3 A:CTD295 4.3 34.5 1.0 C2 A:CTD295 4.4 30.6 1.0 O A:CYS129 4.5 21.7 1.0 C4 A:CTD295 4.5 32.2 1.0 O2 A:CTD295 4.5 31.3 1.0 C A:CYS129 4.7 17.7 1.0 N1 A:CTD295 4.7 27.5 1.0 CA A:HIS102 4.8 18.2 1.0 C5 A:CTD295 4.9 28.6 1.0 N4 A:CTD295 4.9 33.8 1.0 C A:PRO128 5.0 22.6 1.0 CG A:HIS131 5.0 20.2 1.0 C6 A:CTD295 5.0 26.3 1.0

S.Xiang, S.A.Short, R.Wolfenden, C.W.Carter Jr.. Cytidine Deaminase Complexed to 3-Deazacytidine: A "Valence Buffer" in Zinc Enzyme Catalysis. Biochemistry V. 35 1335 1996.
ISSN: ISSN 0006-2960
PubMed: 8634261
DOI: 10.1021/BI9525583