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Zinc in PDB 1aiy: R6 Human Insulin Hexamer (Symmetric), uc(Nmr), 10 Structures

Zinc Binding Sites:

The binding sites of Zinc atom in the R6 Human Insulin Hexamer (Symmetric), uc(Nmr), 10 Structures (pdb code 1aiy). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the R6 Human Insulin Hexamer (Symmetric), uc(Nmr), 10 Structures, PDB code: 1aiy:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 1aiy

Go back to Zinc Binding Sites List in 1aiy
Zinc binding site 1 out of 2 in the R6 Human Insulin Hexamer (Symmetric), uc(Nmr), 10 Structures


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of R6 Human Insulin Hexamer (Symmetric), uc(Nmr), 10 Structures within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn31

b:0.0
occ:1.00
O F:HOH31 2.3 0.0 1.0
NE2 B:HIS10 2.3 0.0 1.0
NE2 J:HIS10 2.4 0.0 1.0
NE2 F:HIS10 2.4 0.0 1.0
H1 F:HOH31 2.4 0.0 1.0
H2 F:HOH31 3.0 0.0 1.0
CE1 B:HIS10 3.2 0.0 1.0
HE1 B:HIS10 3.3 0.0 1.0
CE1 F:HIS10 3.3 0.0 1.0
CE1 J:HIS10 3.4 0.0 1.0
CD2 J:HIS10 3.4 0.0 1.0
CD2 F:HIS10 3.4 0.0 1.0
CD2 B:HIS10 3.4 0.0 1.0
HE1 F:HIS10 3.5 0.0 1.0
HE1 J:HIS10 3.5 0.0 1.0
HD2 J:HIS10 3.6 0.0 1.0
HD2 F:HIS10 3.6 0.0 1.0
HD2 B:HIS10 3.7 0.0 1.0
HB3 J:LEU6 4.0 0.0 1.0
HB3 B:LEU6 4.3 0.0 1.0
HB3 F:LEU6 4.3 0.0 1.0
ND1 B:HIS10 4.4 0.0 1.0
ND1 F:HIS10 4.5 0.0 1.0
ND1 J:HIS10 4.5 0.0 1.0
CG B:HIS10 4.5 0.0 1.0
CG J:HIS10 4.6 0.0 1.0
CG F:HIS10 4.6 0.0 1.0
CB J:LEU6 5.0 0.0 1.0

Zinc binding site 2 out of 2 in 1aiy

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Zinc binding site 2 out of 2 in the R6 Human Insulin Hexamer (Symmetric), uc(Nmr), 10 Structures


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of R6 Human Insulin Hexamer (Symmetric), uc(Nmr), 10 Structures within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn31

b:0.0
occ:1.00
NE2 H:HIS10 2.3 0.0 1.0
H1 H:HOH32 2.4 0.0 1.0
O H:HOH32 2.4 0.0 1.0
NE2 L:HIS10 2.4 0.0 1.0
NE2 D:HIS10 2.4 0.0 1.0
H2 H:HOH32 3.1 0.0 1.0
CE1 H:HIS10 3.2 0.0 1.0
HE1 H:HIS10 3.3 0.0 1.0
CE1 D:HIS10 3.4 0.0 1.0
CE1 L:HIS10 3.4 0.0 1.0
CD2 H:HIS10 3.5 0.0 1.0
CD2 L:HIS10 3.5 0.0 1.0
CD2 D:HIS10 3.5 0.0 1.0
HE1 D:HIS10 3.5 0.0 1.0
HE1 L:HIS10 3.5 0.0 1.0
HD2 L:HIS10 3.7 0.0 1.0
HD2 D:HIS10 3.7 0.0 1.0
HD2 H:HIS10 3.7 0.0 1.0
HB3 L:LEU6 4.1 0.0 1.0
HB3 D:LEU6 4.3 0.0 1.0
HB3 H:LEU6 4.4 0.0 1.0
ND1 H:HIS10 4.5 0.0 1.0
ND1 L:HIS10 4.6 0.0 1.0
ND1 D:HIS10 4.6 0.0 1.0
CG H:HIS10 4.6 0.0 1.0
CG L:HIS10 4.6 0.0 1.0
CG D:HIS10 4.6 0.0 1.0

Reference:

X.Chang, A.M.Jorgensen, P.Bardrum, J.J.Led. Solution Structures of the R6 Human Insulin Hexamer. Biochemistry V. 36 9409 1997.
ISSN: ISSN 0006-2960
PubMed: 9235985
DOI: 10.1021/BI9631069
Page generated: Sat Oct 12 22:03:16 2024

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