Zinc in PDB 9jj1: Cryo-Em Structure of Human ZNT3

The binding sites of Zinc atom in the Cryo-Em Structure of Human ZNT3 (pdb code 9jj1). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 6 binding sites of Zinc where determined in the Cryo-Em Structure of Human ZNT3, PDB code: 9jj1:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6;

Zinc binding site 1 out of 6 in the Cryo-Em Structure of Human ZNT3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Human ZNT3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn801 b:190.3 occ:1.00 OD2 A:ASP242 2.0 129.7 1.0 OD2 A:ASP112 2.0 133.3 1.0 OD1 A:ASP242 2.0 134.8 1.0 CG A:ASP242 2.3 131.7 1.0 NE2 A:HIS108 2.3 121.0 1.0 NE2 A:HIS238 2.3 131.8 1.0 CD2 A:HIS238 2.6 126.0 1.0 CG A:ASP112 3.1 132.0 1.0 CE1 A:HIS108 3.1 115.7 1.0 CD2 A:HIS108 3.2 115.6 1.0 CE1 A:HIS238 3.5 130.0 1.0 OD1 A:ASP112 3.5 135.7 1.0 CB A:ASP242 3.8 127.4 1.0 CG A:HIS238 3.9 122.9 1.0 ND1 A:HIS108 4.1 118.1 1.0 CG A:HIS108 4.2 116.4 1.0 O A:HIS238 4.3 130.9 1.0 ND1 A:HIS238 4.3 129.9 1.0 CB A:ASP112 4.4 123.6 1.0 CA A:ASP242 4.7 119.7 1.0 CBG A:AV0803 4.8 140.2 1.0 C A:HIS238 4.9 125.9 1.0 N A:ASP242 5.0 121.5 1.0

Zinc binding site 2 out of 6 in the Cryo-Em Structure of Human ZNT3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of Human ZNT3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn802 b:257.1 occ:1.00 NE2 A:HIS54 2.0 185.4 1.0 NE2 A:HIS56 2.0 193.1 1.0 SG B:CYS379 2.3 201.3 1.0 SG B:CYS382 2.3 189.3 1.0 CB B:CYS379 2.5 197.3 1.0 CE1 A:HIS54 2.6 187.0 1.0 CD2 A:HIS56 2.6 190.6 1.0 CD2 A:HIS54 3.1 182.7 1.0 CE1 A:HIS56 3.3 189.6 1.0 CB B:CYS382 3.6 183.6 1.0 ND1 A:HIS54 3.6 185.1 1.0 CG A:HIS54 3.9 183.0 1.0 CG A:HIS56 3.9 190.0 1.0 CA B:CYS379 4.1 196.9 1.0 N B:CYS382 4.1 186.2 1.0 ND1 A:HIS56 4.2 188.2 1.0 CB A:ARG57 4.2 199.2 1.0 CG A:ARG57 4.3 197.5 1.0 CA B:CYS382 4.4 184.1 1.0 O A:CYS55 4.5 172.5 1.0 CA A:ARG57 4.5 198.6 1.0 N A:ARG57 4.6 196.9 1.0 C B:CYS379 4.7 196.6 1.0 C A:HIS56 4.8 191.3 1.0 N B:CYS379 4.8 196.9 1.0 C B:ARG381 4.9 193.5 1.0 O A:HIS56 5.0 190.6 1.0 CB B:ARG381 5.0 193.4 1.0

Zinc binding site 3 out of 6 in the Cryo-Em Structure of Human ZNT3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Cryo-Em Structure of Human ZNT3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn804 b:203.5 occ:1.00 OE2 A:GLU370 2.0 125.0 1.0 OE1 A:GLU370 2.0 121.8 1.0 CD A:GLU370 2.1 117.7 1.0 CB A:HIS336 2.3 107.6 1.0 NE2 A:HIS319 2.3 116.5 1.0 ND1 A:HIS336 2.3 101.6 1.0 SG B:CYS55 2.3 159.3 1.0 CG A:HIS336 2.6 103.3 1.0 CE1 A:HIS319 3.1 112.2 1.0 CD2 A:HIS319 3.1 112.3 1.0 CG A:GLU370 3.5 110.3 1.0 CE1 A:HIS336 3.6 101.0 1.0 CA A:HIS336 3.6 95.7 1.0 CB B:CYS55 3.6 165.7 1.0 CD2 A:HIS336 3.9 106.6 1.0 ND1 A:HIS319 4.1 108.8 1.0 NE2 A:GLN368 4.1 108.5 1.0 CG A:HIS319 4.1 109.9 1.0 C A:HIS336 4.2 98.6 1.0 CB A:GLU370 4.3 110.9 1.0 NE2 A:HIS336 4.4 105.3 1.0 CD A:GLN368 4.5 102.2 1.0 O A:HIS336 4.6 110.3 1.0 CG A:GLN368 4.6 97.5 1.0 O A:GLN368 4.7 108.5 1.0 N A:LEU337 4.7 98.2 1.0 N A:HIS336 4.7 100.0 1.0 CA B:CYS55 4.9 167.5 1.0

Zinc binding site 4 out of 6 in the Cryo-Em Structure of Human ZNT3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Cryo-Em Structure of Human ZNT3 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn501 b:195.2 occ:1.00 CE1 B:HIS319 1.6 123.2 1.0 OE2 B:GLU370 2.0 127.2 1.0 OE1 B:GLU370 2.0 125.3 1.0 CD B:GLU370 2.3 118.6 1.0 SG A:CYS55 2.3 173.1 1.0 NE2 B:HIS319 2.3 119.0 1.0 ND1 B:HIS336 2.3 105.1 1.0 ND1 B:HIS319 2.7 117.6 1.0 CB B:HIS336 2.8 104.8 1.0 CG B:HIS336 2.9 102.5 1.0 CD2 B:HIS319 3.5 109.9 1.0 CE1 B:HIS336 3.5 101.5 1.0 CG B:HIS319 3.7 111.9 1.0 CG B:GLU370 3.8 110.2 1.0 CB A:CYS55 4.1 170.0 1.0 CD2 B:HIS336 4.2 103.9 1.0 O A:CYS55 4.2 172.5 1.0 CA B:HIS336 4.3 96.0 1.0 NE2 B:HIS336 4.4 101.2 1.0 NE2 B:GLN368 4.5 108.9 1.0 CB B:GLU370 4.6 111.9 1.0 CE B:MET376 4.8 176.3 1.0 C A:CYS55 4.8 173.5 1.0 C B:HIS336 4.8 99.6 1.0 CA A:CYS55 4.9 171.1 1.0

Zinc binding site 5 out of 6 in the Cryo-Em Structure of Human ZNT3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Cryo-Em Structure of Human ZNT3 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn502 b:187.9 occ:1.00 OD2 B:ASP242 2.0 129.9 1.0 OD2 B:ASP112 2.0 133.1 1.0 OD1 B:ASP242 2.0 136.0 1.0 CG B:ASP242 2.3 132.6 1.0 NE2 B:HIS108 2.3 119.7 1.0 NE2 B:HIS238 2.3 131.7 1.0 CD2 B:HIS238 2.6 126.3 1.0 CG B:ASP112 3.1 131.5 1.0 CE1 B:HIS108 3.1 114.7 1.0 CD2 B:HIS108 3.2 114.1 1.0 CE1 B:HIS238 3.5 130.2 1.0 OD1 B:ASP112 3.5 135.6 1.0 CB B:ASP242 3.8 128.5 1.0 CG B:HIS238 3.9 123.8 1.0 ND1 B:HIS108 4.1 118.0 1.0 CG B:HIS108 4.2 116.1 1.0 O B:HIS238 4.3 131.6 1.0 ND1 B:HIS238 4.3 130.4 1.0 CB B:ASP112 4.4 123.1 1.0 CA B:ASP242 4.7 120.5 1.0 CBG B:AV0504 4.8 140.0 1.0 C B:HIS238 4.9 126.8 1.0 N B:ASP242 5.0 122.5 1.0

Zinc binding site 6 out of 6 in the Cryo-Em Structure of Human ZNT3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Cryo-Em Structure of Human ZNT3 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn503 b:258.5 occ:1.00 NE2 B:HIS54 2.1 185.1 1.0 NE2 B:HIS56 2.1 190.6 1.0 SG A:CYS379 2.3 199.5 1.0 SG A:CYS382 2.3 184.6 1.0 CB A:CYS379 2.7 195.3 1.0 CD2 B:HIS56 2.7 188.6 1.0 CE1 B:HIS54 2.8 186.2 1.0 CD2 B:HIS54 2.9 180.9 1.0 CE1 B:HIS56 3.1 188.0 1.0 CB A:CYS382 3.7 179.3 1.0 ND1 B:HIS54 3.8 184.3 1.0 O B:CYS55 3.8 172.6 1.0 CG B:HIS56 3.8 187.7 1.0 CG B:HIS54 3.9 181.4 1.0 ND1 B:HIS56 4.0 186.6 1.0 N A:CYS382 4.0 181.7 1.0 CA A:CYS379 4.2 195.2 1.0 CG B:ARG57 4.2 197.7 1.0 CB B:ARG57 4.3 198.9 1.0 CA A:CYS382 4.4 179.8 1.0 CA B:ARG57 4.5 198.1 1.0 N B:ARG57 4.6 197.0 1.0 C A:ARG381 4.6 190.4 1.0 CB A:ARG381 4.6 190.7 1.0 C A:CYS379 4.7 194.8 1.0 C B:HIS56 4.7 189.6 1.0 O B:HIS56 4.8 189.1 1.0 N A:ARG381 4.8 193.9 1.0 CD A:ARG381 4.9 191.8 1.0 CA A:ARG381 4.9 191.5 1.0 N A:CYS379 5.0 195.4 1.0

H.Ishida, R.Yo, Z.Zhang, T.Shimizu, U.Ohto. Structural Basis For the Zinc Transporters, ZNT3 and ZNT4 To Be Published.