Zinc in PDB 9ey0: Human Mitochondrial Rnase Z with Trna-His

All present enzymatic activity of Human Mitochondrial Rnase Z with Trna-His:
1.1.1.159; 1.1.1.178; 1.1.1.239; 1.1.1.35; 1.1.1.53; 1.1.1.62; 2.1.1.218; 2.1.1.221; 3.1.26.11;

The binding sites of Zinc atom in the Human Mitochondrial Rnase Z with Trna-His (pdb code 9ey0). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Human Mitochondrial Rnase Z with Trna-His, PDB code: 9ey0:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Human Mitochondrial Rnase Z with Trna-His


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human Mitochondrial Rnase Z with Trna-His within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn901 b:139.2 occ:1.00 OD2 E:ASP666 2.0 94.2 1.0 NE2 E:HIS546 2.0 76.4 1.0 ND1 E:HIS548 2.0 83.3 1.0 NE2 E:HIS644 2.0 78.2 1.0 CE1 E:HIS548 2.6 80.5 1.0 CG E:ASP666 2.8 88.7 1.0 CB E:ASP666 2.9 84.7 1.0 CE1 E:HIS546 2.9 76.1 1.0 CD2 E:HIS644 2.9 81.4 1.0 CE1 E:HIS644 3.0 78.3 1.0 CD2 E:HIS546 3.0 76.3 1.0 CG E:HIS548 3.3 74.8 1.0 ZN E:ZN902 3.7 134.0 1.0 NE2 E:HIS548 3.8 79.1 1.0 CB E:HIS548 3.9 72.8 1.0 OD1 E:ASP666 4.0 87.4 1.0 ND1 E:HIS546 4.0 75.7 1.0 NE2 E:HIS551 4.0 75.8 1.0 CG E:HIS644 4.0 82.2 1.0 ND1 E:HIS644 4.0 81.5 1.0 CG E:HIS546 4.1 71.3 1.0 CD2 E:HIS548 4.2 72.6 1.0 CE1 E:HIS702 4.2 86.9 1.0 CA E:ASP666 4.3 80.9 1.0 CD2 E:HIS551 4.4 74.8 1.0 N E:ASP666 4.8 79.5 1.0 O E:ASP666 4.9 86.9 1.0 CE1 E:HIS551 4.9 76.5 1.0 O3' T:C69 4.9 105.3 1.0 NE2 E:HIS702 5.0 88.0 1.0

Zinc binding site 2 out of 2 in the Human Mitochondrial Rnase Z with Trna-His


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Human Mitochondrial Rnase Z with Trna-His within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn902 b:134.0 occ:1.00 OD2 E:ASP550 2.0 86.2 1.0 OD2 E:ASP666 2.0 94.2 1.0 NE2 E:HIS551 2.0 75.8 1.0 NE2 E:HIS724 2.0 73.9 1.0 CG E:ASP666 2.7 88.7 1.0 CE1 E:HIS724 2.8 70.0 1.0 OD1 E:ASP666 2.8 87.4 1.0 CD2 E:HIS551 2.9 74.8 1.0 CG E:ASP550 3.0 84.1 1.0 CE1 E:HIS551 3.0 76.5 1.0 CD2 E:HIS724 3.2 71.8 1.0 O E:SER490 3.4 94.3 1.0 OD1 E:ASP550 3.4 85.0 1.0 ZN E:ZN901 3.7 139.2 1.0 ND1 E:HIS724 4.0 67.5 1.0 CG E:HIS551 4.1 72.5 1.0 ND1 E:HIS551 4.1 76.8 1.0 CB E:ASP666 4.2 84.7 1.0 CG E:HIS724 4.2 67.7 1.0 NE2 E:HIS546 4.3 76.4 1.0 CB E:ASP550 4.3 78.3 1.0 CE1 E:HIS546 4.4 76.1 1.0 ND1 E:HIS548 4.4 83.3 1.0 C E:SER490 4.5 89.4 1.0 O3' T:C69 4.5 105.3 1.0 CB E:HIS548 4.8 72.8 1.0 O E:ASP550 4.9 88.1 1.0 CA E:SER490 4.9 85.2 1.0 CE1 E:HIS702 5.0 86.9 1.0

G.Valentin Gese, B.M.Hallberg. Structural Basis of 3'-Trna Maturation By the Human Mitochondrial Rnase Z Complex Embo J. 2024.
ISSN: ESSN 1460-2075