Zinc in PDB 8phz: Helical Reconstruction of Chikv NSP3 Helical Scaffolds

All present enzymatic activity of Helical Reconstruction of Chikv NSP3 Helical Scaffolds:
3.1.3.84;

The binding sites of Zinc atom in the Helical Reconstruction of Chikv NSP3 Helical Scaffolds (pdb code 8phz). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 5 binding sites of Zinc where determined in the Helical Reconstruction of Chikv NSP3 Helical Scaffolds, PDB code: 8phz:
Jump to Zinc binding site number: 1; 2; 3; 4; 5;

Zinc binding site 1 out of 5 in the Helical Reconstruction of Chikv NSP3 Helical Scaffolds


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Helical Reconstruction of Chikv NSP3 Helical Scaffolds within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn600 b:51.8 occ:1.00 SG A:CYS264 2.3 30.0 1.0 SG A:CYS262 2.3 16.6 1.0 SG A:CYS287 2.3 27.3 1.0 SG A:CYS305 2.3 18.8 1.0 CB A:CYS287 3.1 20.5 1.0 CB A:CYS262 3.2 22.6 1.0 CB A:CYS305 3.2 27.0 1.0 CB A:CYS264 3.7 20.0 1.0 CB A:SER289 3.9 20.0 1.0 CA A:CYS305 3.9 17.7 1.0 OG A:SER289 4.0 32.7 1.0 N A:CYS264 4.2 21.5 1.0 O A:LYS307 4.4 36.8 1.0 CA A:CYS264 4.5 22.4 1.0 CA A:CYS287 4.5 22.9 1.0 N A:SER289 4.6 29.0 1.0 CA A:CYS262 4.6 24.7 1.0 N A:ALA267 4.8 16.3 1.0 C A:CYS305 4.8 23.4 1.0 N A:LEU263 4.8 30.7 1.0 CA A:SER289 4.8 17.7 1.0 CA A:ALA267 4.9 19.0 1.0 C A:CYS262 4.9 27.7 1.0 N A:SER306 5.0 24.7 1.0 C A:TYR266 5.0 20.2 1.0

Zinc binding site 2 out of 5 in the Helical Reconstruction of Chikv NSP3 Helical Scaffolds


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Helical Reconstruction of Chikv NSP3 Helical Scaffolds within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn600 b:58.0 occ:1.00 SG B:CYS264 2.3 25.1 1.0 SG B:CYS262 2.3 24.4 1.0 SG B:CYS287 2.3 30.8 1.0 SG B:CYS305 2.3 20.9 1.0 CB B:CYS287 3.0 23.4 1.0 CB B:CYS262 3.2 23.4 1.0 CB B:CYS305 3.2 28.4 1.0 CB B:CYS264 3.7 27.4 1.0 CB B:SER289 3.9 20.1 1.0 CA B:CYS305 3.9 20.4 1.0 OG B:SER289 4.1 28.9 1.0 N B:CYS264 4.2 21.2 1.0 O B:LYS307 4.4 34.3 1.0 CA B:CYS264 4.5 19.5 1.0 CA B:CYS287 4.5 22.6 1.0 CA B:CYS262 4.5 23.3 1.0 N B:SER289 4.6 24.2 1.0 N B:ALA267 4.8 14.5 1.0 C B:CYS305 4.8 24.7 1.0 N B:LEU263 4.8 27.9 1.0 C B:CYS262 4.8 28.9 1.0 CA B:SER289 4.9 20.9 1.0 C B:TYR266 4.9 20.4 1.0 CA B:ALA267 4.9 23.3 1.0 N B:SER306 4.9 27.8 1.0

Zinc binding site 3 out of 5 in the Helical Reconstruction of Chikv NSP3 Helical Scaffolds


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Helical Reconstruction of Chikv NSP3 Helical Scaffolds within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn600 b:52.8 occ:1.00 SG C:CYS262 2.3 23.9 1.0 SG C:CYS264 2.3 23.8 1.0 SG C:CYS287 2.3 26.6 1.0 SG C:CYS305 2.3 18.0 1.0 CB C:CYS287 3.0 21.3 1.0 CB C:CYS262 3.2 15.7 1.0 CB C:CYS305 3.2 20.1 1.0 CB C:CYS264 3.7 18.8 1.0 CA C:CYS305 3.9 20.0 1.0 CB C:SER289 3.9 16.4 1.0 OG C:SER289 4.1 29.6 1.0 N C:CYS264 4.2 17.3 1.0 O C:LYS307 4.4 31.4 1.0 CA C:CYS264 4.5 22.5 1.0 CA C:CYS287 4.5 14.0 1.0 CA C:CYS262 4.6 20.3 1.0 N C:SER289 4.7 24.9 1.0 C C:CYS305 4.8 25.4 1.0 N C:LEU263 4.8 31.4 1.0 N C:ALA267 4.8 20.6 1.0 C C:CYS262 4.9 26.6 1.0 N C:SER306 4.9 26.4 1.0 C C:TYR266 4.9 18.1 1.0 CA C:SER289 4.9 22.0 1.0 CA C:ALA267 4.9 23.7 1.0

Zinc binding site 4 out of 5 in the Helical Reconstruction of Chikv NSP3 Helical Scaffolds


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Helical Reconstruction of Chikv NSP3 Helical Scaffolds within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn600 b:50.7 occ:1.00 SG D:CYS264 2.3 27.3 1.0 SG D:CYS287 2.3 26.1 1.0 SG D:CYS262 2.3 16.7 1.0 SG D:CYS305 2.3 17.1 1.0 CB D:CYS287 3.2 17.4 1.0 CB D:CYS262 3.2 21.9 1.0 CB D:CYS305 3.3 25.7 1.0 CB D:CYS264 3.7 20.6 1.0 CB D:SER289 3.8 22.1 1.0 OG D:SER289 3.9 33.8 1.0 CA D:CYS305 4.0 17.4 1.0 N D:CYS264 4.2 18.0 1.0 O D:LYS307 4.3 38.5 1.0 CA D:CYS264 4.5 20.0 1.0 N D:SER289 4.5 21.6 1.0 CA D:CYS262 4.6 18.3 1.0 CA D:CYS287 4.6 19.4 1.0 CA D:SER289 4.8 22.3 1.0 C D:CYS305 4.8 20.6 1.0 N D:LEU263 4.8 24.4 1.0 N D:ALA267 4.9 17.1 1.0 C D:CYS262 4.9 22.8 1.0 N D:SER306 4.9 28.0 1.0 C D:TYR266 5.0 18.7 1.0 CA D:ALA267 5.0 15.4 1.0

Zinc binding site 5 out of 5 in the Helical Reconstruction of Chikv NSP3 Helical Scaffolds


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Helical Reconstruction of Chikv NSP3 Helical Scaffolds within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn600 b:55.1 occ:1.00 SG E:CYS264 2.3 30.3 1.0 SG E:CYS262 2.3 20.2 1.0 SG E:CYS287 2.3 18.9 1.0 SG E:CYS305 2.3 21.4 1.0 CB E:CYS287 3.1 12.3 1.0 CB E:CYS262 3.2 18.1 1.0 CB E:CYS305 3.2 23.2 1.0 CB E:CYS264 3.6 15.9 1.0 CB E:SER289 3.8 13.4 1.0 CA E:CYS305 3.9 14.3 1.0 OG E:SER289 3.9 28.4 1.0 N E:CYS264 4.2 16.6 1.0 O E:LYS307 4.4 32.1 1.0 CA E:CYS264 4.5 17.8 1.0 N E:SER289 4.5 21.1 1.0 CA E:CYS262 4.6 22.4 1.0 CA E:CYS287 4.6 16.1 1.0 C E:CYS305 4.8 27.8 1.0 CA E:SER289 4.8 22.6 1.0 N E:LEU263 4.8 23.8 1.0 N E:ALA267 4.8 23.3 1.0 C E:CYS262 4.9 22.6 1.0 N E:SER306 4.9 25.5 1.0 CA E:ALA267 4.9 19.8 1.0

J.Reguera, M.Hons, C.Zimberger, D.Ptchelkine, R.Jones, A.Desfosses. The Alphavirus NSP3 Protein Forms Helical Tubular Scaffolds Important For Viral Replication and Particle Assembly To Be Published.