Zinc in PDB 7uob: Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State

All present enzymatic activity of Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State:
2.7.7.48;

The structure of Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State also contains other interesting chemical elements:

Magnesium

(Mg)

3 atoms

The binding sites of Zinc atom in the Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State (pdb code 7uob). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State, PDB code: 7uob:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:39.7 occ:1.00 ND1 A:HIS295 2.2 6.7 1.0 SG A:CYS310 2.3 6.8 1.0 SG A:CYS306 2.3 7.0 1.0 SG A:CYS301 2.3 6.5 1.0 CE1 A:HIS295 3.2 6.7 1.0 CG A:HIS295 3.2 6.7 1.0 O A:CYS306 3.3 7.0 1.0 CB A:CYS310 3.4 6.8 1.0 CB A:CYS301 3.4 6.5 1.0 CB A:HIS295 3.5 6.7 1.0 CB A:CYS306 3.7 7.0 1.0 C A:CYS306 3.8 7.0 1.0 CA A:CYS301 3.9 6.5 1.0 N A:HIS295 4.1 6.7 1.0 O A:HOH1159 4.1 6.7 1.0 CA A:CYS306 4.2 7.0 1.0 NE2 A:HIS295 4.3 6.7 1.0 CD2 A:HIS295 4.3 6.7 1.0 CA A:HIS295 4.4 6.7 1.0 N A:ILE307 4.6 6.5 1.0 O A:THR293 4.6 5.7 1.0 N A:CYS301 4.7 6.5 1.0 CA A:CYS310 4.7 6.8 1.0 N A:CYS310 4.7 6.8 1.0 O A:HIS295 4.8 6.7 1.0 N A:LEU302 5.0 6.7 1.0 CA A:ILE307 5.0 6.5 1.0

Zinc binding site 2 out of 2 in the Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre- Catalytic State within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1002 b:36.8 occ:1.00 ND1 A:HIS642 2.2 5.9 1.0 SG A:CYS646 2.3 6.5 1.0 SG A:CYS487 2.3 5.3 1.0 SG A:CYS645 2.3 7.7 1.0 CG A:HIS642 3.1 5.9 1.0 CB A:HIS642 3.3 5.9 1.0 CE1 A:HIS642 3.3 5.9 1.0 CB A:CYS645 3.4 7.7 1.0 CB A:CYS646 3.6 6.5 1.0 CB A:CYS487 3.7 5.3 1.0 N A:CYS487 3.9 5.3 1.0 N A:CYS646 4.0 6.5 1.0 C A:CYS645 4.0 7.7 1.0 CA A:HIS642 4.1 5.9 1.0 CE1 A:PHE571 4.2 5.4 1.0 CD2 A:HIS642 4.3 5.9 1.0 CA A:CYS645 4.3 7.7 1.0 NE2 A:HIS642 4.3 5.9 1.0 CA A:CYS646 4.4 6.5 1.0 CA A:CYS487 4.4 5.3 1.0 O A:CYS645 4.5 7.7 1.0 O A:HIS642 4.6 5.9 1.0 CD1 A:PHE571 4.6 5.4 1.0 C A:GLY486 4.7 4.2 1.0 C A:HIS642 4.8 5.9 1.0 N A:CYS645 4.8 7.7 1.0 CA A:GLY486 4.9 4.2 1.0 NZ A:LYS532 5.0 5.3 1.0

B.F.Malone, S.A.Darst. Sars-Cov-2 Replication-Transcription Complex Bound to Gtp, in A Pre-Catalytic State To Be Published.