Zinc »
PDB 7sfg-7syg »
7sgi »
Zinc in PDB 7sgi: Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Inhibitor 14
Enzymatic activity of Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Inhibitor 14
All present enzymatic activity of Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Inhibitor 14:
3.5.1.48; 3.5.1.62;
3.5.1.48; 3.5.1.62;
Protein crystallography data
The structure of Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Inhibitor 14, PDB code: 7sgi
was solved by
C.J.Herbst-Gervasoni,
D.W.Christianson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 69.71 / 2.15 |
| Space group | P 31 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 80.5, 80.5, 246.632, 90, 90, 120 |
| R / Rfree (%) | 19 / 22.2 |
Other elements in 7sgi:
The structure of Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Inhibitor 14 also contains other interesting chemical elements:
| Sodium | (Na) | 1 atom |
| Potassium | (K) | 2 atoms |
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Inhibitor 14
(pdb code 7sgi). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Inhibitor 14, PDB code: 7sgi:
In total only one binding site of Zinc was determined in the Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Inhibitor 14, PDB code: 7sgi:
Zinc binding site 1 out of 1 in 7sgi
Go back to
Zinc Binding Sites List in 7sgi
Zinc binding site 1 out
of 1 in the Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Inhibitor 14
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Inhibitor 14 within 5.0Å range:
|
Reference:
R.R.Steimbach,
C.J.Herbst-Gervasoni,
S.Lechner,
T.M.Stewart,
G.Klinke,
J.Ridinger,
M.N.E.Geraldy,
G.Tihanyi,
J.R.Foley,
U.Uhrig,
B.Kuster,
G.Poschet,
R.A.Casero Jr.,
G.Medard,
I.Oehme,
D.W.Christianson,
N.Gunkel,
A.K.Miller.
Aza-Saha Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout. J.Am.Chem.Soc. V. 144 18861 2022.
ISSN: ESSN 1520-5126
PubMed: 36200994
DOI: 10.1021/JACS.2C05030
Page generated: Fri Aug 22 04:41:30 2025
ISSN: ESSN 1520-5126
PubMed: 36200994
DOI: 10.1021/JACS.2C05030
Last articles
Zn in 8JE2Zn in 8JE1
Zn in 8JCE
Zn in 8JAV
Zn in 8JAS
Zn in 8JB5
Zn in 8JAQ
Zn in 8J85
Zn in 8J9Q
Zn in 8JAR
