Zinc in PDB 6foi: Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated.
Enzymatic activity of Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated.
All present enzymatic activity of Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated.:
1.15.1.1;
Protein crystallography data
The structure of Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated., PDB code: 6foi
was solved by
G.S.A.Wright,
F.A.Sala,
S.V.Antonyuk,
R.C.Garratt,
S.S.Hasnain,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
81.48 /
2.00
|
|
Space group
|
P 21 21 21
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
74.650,
162.959,
174.601,
90.00,
90.00,
90.00
|
|
R / Rfree (%)
|
22.1 /
25.9
|
Zinc Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
12;
Binding sites:
The binding sites of Zinc atom in the Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated.
(pdb code 6foi). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 12 binding sites of Zinc where determined in the
Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated., PDB code: 6foi:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Zinc binding site 1 out
of 12 in 6foi
Go back to
Zinc Binding Sites List in 6foi
Zinc binding site 1 out
of 12 in the Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated.
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated. within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn201
b:25.4
occ:1.00
|
OD1
|
A:ASP83
|
1.9
|
25.8
|
1.0
|
|
ND1
|
A:HIS71
|
2.0
|
28.0
|
1.0
|
|
ND1
|
A:HIS63
|
2.1
|
25.9
|
1.0
|
|
ND1
|
A:HIS80
|
2.2
|
27.0
|
1.0
|
|
CG
|
A:ASP83
|
2.7
|
26.5
|
1.0
|
|
OD2
|
A:ASP83
|
2.9
|
27.3
|
1.0
|
|
CE1
|
A:HIS71
|
2.9
|
27.8
|
1.0
|
|
CE1
|
A:HIS63
|
3.0
|
26.0
|
1.0
|
|
CE1
|
A:HIS80
|
3.0
|
27.9
|
1.0
|
|
CG
|
A:HIS63
|
3.1
|
25.4
|
1.0
|
|
CG
|
A:HIS71
|
3.1
|
29.0
|
1.0
|
|
CG
|
A:HIS80
|
3.2
|
27.2
|
1.0
|
|
CB
|
A:HIS63
|
3.5
|
25.4
|
1.0
|
|
CB
|
A:HIS80
|
3.6
|
26.6
|
1.0
|
|
CB
|
A:HIS71
|
3.6
|
29.8
|
1.0
|
|
O
|
A:LYS136
|
3.6
|
29.3
|
1.0
|
|
CA
|
A:HIS71
|
3.9
|
30.2
|
1.0
|
|
NE2
|
A:HIS71
|
4.1
|
28.6
|
1.0
|
|
NE2
|
A:HIS80
|
4.1
|
28.6
|
1.0
|
|
NE2
|
A:HIS63
|
4.1
|
25.7
|
1.0
|
|
CB
|
A:ASP83
|
4.2
|
26.6
|
1.0
|
|
CD2
|
A:HIS71
|
4.2
|
29.4
|
1.0
|
|
CD2
|
A:HIS63
|
4.2
|
25.3
|
1.0
|
|
CD2
|
A:HIS80
|
4.2
|
28.2
|
1.0
|
|
CA
|
A:ASP83
|
4.7
|
25.8
|
1.0
|
|
N
|
A:GLY72
|
4.7
|
30.4
|
1.0
|
|
C
|
A:LYS136
|
4.7
|
30.1
|
1.0
|
|
N
|
A:HIS80
|
4.7
|
28.4
|
1.0
|
|
O
|
A:HOH330
|
4.7
|
22.0
|
1.0
|
|
CA
|
A:HIS80
|
4.8
|
27.5
|
1.0
|
|
C
|
A:HIS71
|
4.9
|
30.9
|
1.0
|
|
N
|
A:HIS71
|
4.9
|
31.3
|
1.0
|
|
N
|
A:ASP83
|
4.9
|
25.3
|
1.0
|
|
CA
|
A:HIS63
|
5.0
|
25.1
|
1.0
|
|
Zinc binding site 2 out
of 12 in 6foi
Go back to
Zinc Binding Sites List in 6foi
Zinc binding site 2 out
of 12 in the Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated.
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated. within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Zn201
b:25.5
occ:1.00
|
OD1
|
F:ASP83
|
1.8
|
24.4
|
1.0
|
|
ND1
|
F:HIS63
|
2.1
|
24.8
|
1.0
|
|
ND1
|
F:HIS71
|
2.1
|
26.6
|
1.0
|
|
ND1
|
F:HIS80
|
2.2
|
27.4
|
1.0
|
|
CG
|
F:ASP83
|
2.7
|
25.2
|
1.0
|
|
CE1
|
F:HIS71
|
3.0
|
26.0
|
1.0
|
|
OD2
|
F:ASP83
|
3.0
|
26.2
|
1.0
|
|
CE1
|
F:HIS63
|
3.0
|
24.7
|
1.0
|
|
CE1
|
F:HIS80
|
3.1
|
28.6
|
1.0
|
|
CG
|
F:HIS63
|
3.1
|
24.5
|
1.0
|
|
CG
|
F:HIS80
|
3.1
|
27.7
|
1.0
|
|
CG
|
F:HIS71
|
3.2
|
27.9
|
1.0
|
|
CB
|
F:HIS63
|
3.4
|
24.8
|
1.0
|
|
CB
|
F:HIS80
|
3.5
|
26.8
|
1.0
|
|
CB
|
F:HIS71
|
3.6
|
29.1
|
1.0
|
|
O
|
F:LYS136
|
3.8
|
30.1
|
1.0
|
|
CA
|
F:HIS71
|
3.9
|
29.6
|
1.0
|
|
NE2
|
F:HIS71
|
4.1
|
26.7
|
1.0
|
|
NE2
|
F:HIS80
|
4.2
|
29.7
|
1.0
|
|
NE2
|
F:HIS63
|
4.2
|
24.3
|
1.0
|
|
CB
|
F:ASP83
|
4.2
|
24.9
|
1.0
|
|
CD2
|
F:HIS80
|
4.2
|
29.1
|
1.0
|
|
CD2
|
F:HIS63
|
4.2
|
24.2
|
1.0
|
|
CD2
|
F:HIS71
|
4.3
|
27.9
|
1.0
|
|
O
|
F:HOH326
|
4.5
|
26.2
|
1.0
|
|
CA
|
F:ASP83
|
4.7
|
24.0
|
1.0
|
|
N
|
F:HIS80
|
4.7
|
28.3
|
1.0
|
|
CA
|
F:HIS80
|
4.7
|
27.6
|
1.0
|
|
N
|
F:GLY72
|
4.8
|
29.2
|
1.0
|
|
C
|
F:LYS136
|
4.9
|
31.0
|
1.0
|
|
N
|
F:HIS71
|
4.9
|
31.1
|
1.0
|
|
C
|
F:HIS71
|
4.9
|
30.0
|
1.0
|
|
N
|
F:ASP83
|
4.9
|
23.9
|
1.0
|
|
CA
|
F:HIS63
|
4.9
|
24.7
|
1.0
|
|
Zinc binding site 3 out
of 12 in 6foi
Go back to
Zinc Binding Sites List in 6foi
Zinc binding site 3 out
of 12 in the Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated.
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated. within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn201
b:28.5
occ:1.00
|
OD1
|
D:ASP83
|
2.0
|
30.0
|
1.0
|
|
ND1
|
D:HIS63
|
2.0
|
29.5
|
1.0
|
|
ND1
|
D:HIS71
|
2.0
|
31.6
|
1.0
|
|
ND1
|
D:HIS80
|
2.1
|
30.6
|
1.0
|
|
CG
|
D:ASP83
|
2.8
|
30.5
|
1.0
|
|
CE1
|
D:HIS71
|
2.9
|
31.6
|
1.0
|
|
CE1
|
D:HIS63
|
2.9
|
29.8
|
1.0
|
|
CE1
|
D:HIS80
|
3.0
|
31.5
|
1.0
|
|
OD2
|
D:ASP83
|
3.0
|
31.4
|
1.0
|
|
CG
|
D:HIS63
|
3.0
|
28.8
|
1.0
|
|
CG
|
D:HIS80
|
3.1
|
30.6
|
1.0
|
|
CG
|
D:HIS71
|
3.1
|
32.8
|
1.0
|
|
CB
|
D:HIS63
|
3.4
|
28.5
|
1.0
|
|
CB
|
D:HIS80
|
3.5
|
29.9
|
1.0
|
|
CB
|
D:HIS71
|
3.6
|
33.4
|
1.0
|
|
O
|
D:LYS136
|
3.8
|
31.7
|
1.0
|
|
CA
|
D:HIS71
|
3.9
|
33.7
|
1.0
|
|
NE2
|
D:HIS80
|
4.1
|
32.2
|
1.0
|
|
NE2
|
D:HIS63
|
4.1
|
29.4
|
1.0
|
|
NE2
|
D:HIS71
|
4.1
|
32.7
|
1.0
|
|
CD2
|
D:HIS63
|
4.1
|
28.8
|
1.0
|
|
CD2
|
D:HIS80
|
4.1
|
31.7
|
1.0
|
|
CD2
|
D:HIS71
|
4.2
|
33.5
|
1.0
|
|
CB
|
D:ASP83
|
4.3
|
30.5
|
1.0
|
|
CA
|
D:ASP83
|
4.7
|
29.4
|
1.0
|
|
N
|
D:HIS80
|
4.7
|
31.8
|
1.0
|
|
CA
|
D:HIS80
|
4.8
|
30.7
|
1.0
|
|
N
|
D:GLY72
|
4.8
|
34.2
|
1.0
|
|
C
|
D:LYS136
|
4.8
|
32.7
|
1.0
|
|
C
|
D:HIS71
|
4.9
|
34.6
|
1.0
|
|
N
|
D:HIS71
|
4.9
|
34.5
|
1.0
|
|
N
|
D:ASP83
|
4.9
|
28.6
|
1.0
|
|
CA
|
D:HIS63
|
4.9
|
28.0
|
1.0
|
|
O
|
D:HOH361
|
5.0
|
31.7
|
1.0
|
|
Zinc binding site 4 out
of 12 in 6foi
Go back to
Zinc Binding Sites List in 6foi
Zinc binding site 4 out
of 12 in the Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated.
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated. within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Zn201
b:23.9
occ:1.00
|
OD1
|
G:ASP83
|
1.8
|
24.3
|
1.0
|
|
ND1
|
G:HIS63
|
2.1
|
24.5
|
1.0
|
|
ND1
|
G:HIS71
|
2.1
|
25.3
|
1.0
|
|
ND1
|
G:HIS80
|
2.2
|
26.2
|
1.0
|
|
CG
|
G:ASP83
|
2.7
|
25.0
|
1.0
|
|
OD2
|
G:ASP83
|
2.9
|
25.7
|
1.0
|
|
CE1
|
G:HIS71
|
2.9
|
24.8
|
1.0
|
|
CE1
|
G:HIS63
|
3.0
|
24.2
|
1.0
|
|
CE1
|
G:HIS80
|
3.1
|
27.0
|
1.0
|
|
CG
|
G:HIS63
|
3.1
|
24.4
|
1.0
|
|
CG
|
G:HIS80
|
3.1
|
26.8
|
1.0
|
|
CG
|
G:HIS71
|
3.2
|
26.2
|
1.0
|
|
CB
|
G:HIS63
|
3.4
|
24.9
|
1.0
|
|
CB
|
G:HIS80
|
3.5
|
26.4
|
1.0
|
|
CB
|
G:HIS71
|
3.7
|
27.2
|
1.0
|
|
O
|
G:LYS136
|
3.8
|
28.0
|
1.0
|
|
CA
|
G:HIS71
|
4.0
|
27.9
|
1.0
|
|
NE2
|
G:HIS71
|
4.1
|
25.1
|
1.0
|
|
CB
|
G:ASP83
|
4.1
|
25.0
|
1.0
|
|
NE2
|
G:HIS80
|
4.2
|
28.0
|
1.0
|
|
NE2
|
G:HIS63
|
4.2
|
23.9
|
1.0
|
|
CD2
|
G:HIS80
|
4.2
|
27.9
|
1.0
|
|
CD2
|
G:HIS63
|
4.2
|
24.1
|
1.0
|
|
CD2
|
G:HIS71
|
4.3
|
26.0
|
1.0
|
|
CA
|
G:ASP83
|
4.6
|
24.4
|
1.0
|
|
O
|
G:HOH363
|
4.7
|
31.0
|
1.0
|
|
N
|
G:HIS80
|
4.7
|
27.9
|
1.0
|
|
CA
|
G:HIS80
|
4.7
|
27.4
|
1.0
|
|
N
|
G:GLY72
|
4.8
|
27.9
|
1.0
|
|
C
|
G:LYS136
|
4.8
|
28.5
|
1.0
|
|
N
|
G:ASP83
|
4.9
|
24.6
|
1.0
|
|
CA
|
G:HIS63
|
4.9
|
24.9
|
1.0
|
|
C
|
G:HIS71
|
5.0
|
28.4
|
1.0
|
|
N
|
G:HIS71
|
5.0
|
29.1
|
1.0
|
|
Zinc binding site 5 out
of 12 in 6foi
Go back to
Zinc Binding Sites List in 6foi
Zinc binding site 5 out
of 12 in the Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated.
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated. within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
I:Zn201
b:39.8
occ:1.00
|
OD1
|
I:ASP83
|
1.9
|
44.3
|
1.0
|
|
ND1
|
I:HIS63
|
2.0
|
41.7
|
1.0
|
|
ND1
|
I:HIS71
|
2.2
|
44.3
|
1.0
|
|
ND1
|
I:HIS80
|
2.2
|
43.1
|
1.0
|
|
CG
|
I:ASP83
|
2.8
|
45.3
|
1.0
|
|
OD2
|
I:ASP83
|
2.9
|
45.8
|
1.0
|
|
CE1
|
I:HIS63
|
3.0
|
41.9
|
1.0
|
|
CG
|
I:HIS63
|
3.0
|
40.8
|
1.0
|
|
CE1
|
I:HIS71
|
3.0
|
44.8
|
1.0
|
|
CE1
|
I:HIS80
|
3.1
|
43.4
|
1.0
|
|
CG
|
I:HIS80
|
3.2
|
43.9
|
1.0
|
|
CG
|
I:HIS71
|
3.2
|
45.1
|
1.0
|
|
CB
|
I:HIS63
|
3.3
|
40.6
|
1.0
|
|
CB
|
I:HIS80
|
3.5
|
44.2
|
1.0
|
|
CB
|
I:HIS71
|
3.6
|
45.2
|
1.0
|
|
O
|
I:LYS136
|
3.8
|
41.9
|
1.0
|
|
CA
|
I:HIS71
|
3.9
|
46.1
|
1.0
|
|
NE2
|
I:HIS63
|
4.1
|
41.2
|
1.0
|
|
CD2
|
I:HIS63
|
4.1
|
40.5
|
1.0
|
|
NE2
|
I:HIS80
|
4.2
|
44.2
|
1.0
|
|
NE2
|
I:HIS71
|
4.2
|
45.8
|
1.0
|
|
CB
|
I:ASP83
|
4.2
|
46.4
|
1.0
|
|
CD2
|
I:HIS80
|
4.2
|
44.6
|
1.0
|
|
CD2
|
I:HIS71
|
4.3
|
46.0
|
1.0
|
|
CA
|
I:ASP83
|
4.7
|
45.8
|
1.0
|
|
CA
|
I:HIS80
|
4.7
|
45.8
|
1.0
|
|
N
|
I:GLY72
|
4.8
|
47.8
|
1.0
|
|
N
|
I:HIS80
|
4.8
|
47.0
|
1.0
|
|
C
|
I:LYS136
|
4.8
|
42.4
|
1.0
|
|
CA
|
I:HIS63
|
4.9
|
39.8
|
1.0
|
|
N
|
I:ASP83
|
4.9
|
45.1
|
1.0
|
|
C
|
I:HIS71
|
4.9
|
47.6
|
1.0
|
|
N
|
I:HIS71
|
4.9
|
46.5
|
1.0
|
|
Zinc binding site 6 out
of 12 in 6foi
Go back to
Zinc Binding Sites List in 6foi
Zinc binding site 6 out
of 12 in the Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated.
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated. within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
K:Zn201
b:33.1
occ:1.00
|
ND1
|
K:HIS71
|
1.9
|
34.0
|
1.0
|
|
ND1
|
K:HIS80
|
2.0
|
35.7
|
1.0
|
|
OD1
|
K:ASP83
|
2.1
|
31.8
|
1.0
|
|
ND1
|
K:HIS63
|
2.1
|
36.9
|
1.0
|
|
CE1
|
K:HIS80
|
2.7
|
37.2
|
1.0
|
|
CG
|
K:ASP83
|
2.8
|
31.0
|
1.0
|
|
CE1
|
K:HIS71
|
2.8
|
33.3
|
1.0
|
|
OD2
|
K:ASP83
|
2.9
|
31.3
|
1.0
|
|
CE1
|
K:HIS63
|
3.0
|
37.3
|
1.0
|
|
CG
|
K:HIS71
|
3.0
|
34.6
|
1.0
|
|
CG
|
K:HIS63
|
3.1
|
37.8
|
1.0
|
|
CG
|
K:HIS80
|
3.1
|
35.5
|
1.0
|
|
CB
|
K:HIS63
|
3.4
|
37.9
|
1.0
|
|
CB
|
K:HIS71
|
3.5
|
35.8
|
1.0
|
|
CB
|
K:HIS80
|
3.7
|
34.2
|
1.0
|
|
O
|
K:LYS136
|
3.9
|
40.9
|
1.0
|
|
NE2
|
K:HIS80
|
3.9
|
37.8
|
1.0
|
|
CA
|
K:HIS71
|
3.9
|
35.1
|
1.0
|
|
NE2
|
K:HIS71
|
4.0
|
33.2
|
1.0
|
|
CD2
|
K:HIS80
|
4.1
|
36.8
|
1.0
|
|
CD2
|
K:HIS71
|
4.1
|
34.0
|
1.0
|
|
NE2
|
K:HIS63
|
4.2
|
38.5
|
1.0
|
|
CD2
|
K:HIS63
|
4.2
|
38.8
|
1.0
|
|
CB
|
K:ASP83
|
4.2
|
29.8
|
1.0
|
|
CA
|
K:ASP83
|
4.8
|
29.6
|
1.0
|
|
N
|
K:GLY72
|
4.8
|
32.6
|
1.0
|
|
N
|
K:HIS80
|
4.8
|
33.0
|
1.0
|
|
C
|
K:LYS136
|
4.8
|
41.6
|
1.0
|
|
C
|
K:HIS71
|
4.9
|
33.9
|
1.0
|
|
CA
|
K:HIS80
|
4.9
|
33.6
|
1.0
|
|
N
|
K:HIS71
|
4.9
|
36.5
|
1.0
|
|
O
|
K:HOH347
|
4.9
|
40.2
|
1.0
|
|
N
|
K:ASP83
|
5.0
|
30.2
|
1.0
|
|
CA
|
K:HIS63
|
5.0
|
39.2
|
1.0
|
|
Zinc binding site 7 out
of 12 in 6foi
Go back to
Zinc Binding Sites List in 6foi
Zinc binding site 7 out
of 12 in the Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated.
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated. within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
M:Zn201
b:25.7
occ:1.00
|
OD1
|
M:ASP83
|
1.9
|
26.6
|
1.0
|
|
ND1
|
M:HIS80
|
2.1
|
28.4
|
1.0
|
|
ND1
|
M:HIS71
|
2.2
|
27.7
|
1.0
|
|
ND1
|
M:HIS63
|
2.2
|
28.5
|
1.0
|
|
CG
|
M:ASP83
|
2.7
|
26.6
|
1.0
|
|
OD2
|
M:ASP83
|
2.8
|
26.5
|
1.0
|
|
CE1
|
M:HIS80
|
3.0
|
28.8
|
1.0
|
|
CE1
|
M:HIS71
|
3.0
|
27.5
|
1.0
|
|
CG
|
M:HIS80
|
3.1
|
28.5
|
1.0
|
|
CE1
|
M:HIS63
|
3.1
|
28.8
|
1.0
|
|
CG
|
M:HIS63
|
3.2
|
29.3
|
1.0
|
|
CG
|
M:HIS71
|
3.3
|
27.8
|
1.0
|
|
CB
|
M:HIS63
|
3.4
|
29.5
|
1.0
|
|
CB
|
M:HIS80
|
3.5
|
28.3
|
1.0
|
|
CB
|
M:HIS71
|
3.7
|
28.3
|
1.0
|
|
O
|
M:LYS136
|
3.7
|
30.1
|
1.0
|
|
CA
|
M:HIS71
|
4.0
|
28.3
|
1.0
|
|
NE2
|
M:HIS80
|
4.1
|
29.2
|
1.0
|
|
CD2
|
M:HIS80
|
4.1
|
29.1
|
1.0
|
|
CB
|
M:ASP83
|
4.1
|
26.6
|
1.0
|
|
NE2
|
M:HIS71
|
4.2
|
27.6
|
1.0
|
|
NE2
|
M:HIS63
|
4.3
|
29.6
|
1.0
|
|
CD2
|
M:HIS63
|
4.3
|
29.9
|
1.0
|
|
CD2
|
M:HIS71
|
4.3
|
27.7
|
1.0
|
|
N
|
M:HIS80
|
4.7
|
28.1
|
1.0
|
|
CA
|
M:ASP83
|
4.7
|
27.0
|
1.0
|
|
CA
|
M:HIS80
|
4.7
|
28.4
|
1.0
|
|
C
|
M:LYS136
|
4.8
|
30.7
|
1.0
|
|
N
|
M:GLY72
|
4.8
|
27.7
|
1.0
|
|
O
|
M:HOH345
|
4.8
|
27.7
|
1.0
|
|
N
|
M:ASP83
|
4.9
|
27.4
|
1.0
|
|
C
|
M:HIS71
|
5.0
|
28.0
|
1.0
|
|
CA
|
M:HIS63
|
5.0
|
30.6
|
1.0
|
|
N
|
M:HIS71
|
5.0
|
29.1
|
1.0
|
|
Zinc binding site 8 out
of 12 in 6foi
Go back to
Zinc Binding Sites List in 6foi
Zinc binding site 8 out
of 12 in the Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated.
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 8 of Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated. within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
O:Zn201
b:64.9
occ:1.00
|
OD1
|
O:ASP83
|
2.1
|
68.3
|
1.0
|
|
ND1
|
O:HIS63
|
2.2
|
68.7
|
1.0
|
|
ND1
|
O:HIS80
|
2.2
|
70.5
|
1.0
|
|
ND1
|
O:HIS71
|
2.3
|
74.2
|
1.0
|
|
CG
|
O:ASP83
|
2.8
|
69.2
|
1.0
|
|
OD2
|
O:ASP83
|
2.9
|
70.4
|
1.0
|
|
CE1
|
O:HIS80
|
3.1
|
72.8
|
1.0
|
|
CG
|
O:HIS63
|
3.1
|
66.7
|
1.0
|
|
CE1
|
O:HIS63
|
3.2
|
69.8
|
1.0
|
|
CE1
|
O:HIS71
|
3.2
|
74.4
|
1.0
|
|
CG
|
O:HIS80
|
3.2
|
69.9
|
1.0
|
|
CG
|
O:HIS71
|
3.3
|
77.1
|
1.0
|
|
CB
|
O:HIS63
|
3.3
|
65.3
|
1.0
|
|
CB
|
O:HIS80
|
3.6
|
67.7
|
1.0
|
|
CB
|
O:HIS71
|
3.6
|
77.9
|
1.0
|
|
O
|
O:LYS136
|
3.9
|
74.9
|
0.8
|
|
CA
|
O:HIS71
|
3.9
|
77.7
|
1.0
|
|
NE2
|
O:HIS80
|
4.1
|
73.7
|
1.0
|
|
CD2
|
O:HIS80
|
4.2
|
71.9
|
1.0
|
|
CD2
|
O:HIS63
|
4.3
|
66.5
|
1.0
|
|
CB
|
O:ASP83
|
4.3
|
68.8
|
1.0
|
|
NE2
|
O:HIS63
|
4.3
|
68.5
|
1.0
|
|
NE2
|
O:HIS71
|
4.3
|
77.3
|
1.0
|
|
CD2
|
O:HIS71
|
4.4
|
79.0
|
1.0
|
|
N
|
O:GLY72
|
4.7
|
78.0
|
1.0
|
|
N
|
O:HIS80
|
4.7
|
70.9
|
1.0
|
|
CA
|
O:HIS80
|
4.8
|
68.4
|
1.0
|
|
CA
|
O:HIS63
|
4.8
|
63.5
|
1.0
|
|
C
|
O:HIS71
|
4.9
|
79.5
|
1.0
|
|
CA
|
O:ASP83
|
4.9
|
66.4
|
1.0
|
|
C
|
O:LYS136
|
4.9
|
77.5
|
0.8
|
|
N
|
O:HIS71
|
4.9
|
79.1
|
1.0
|
|
N
|
O:ASP83
|
5.0
|
64.3
|
1.0
|
|
Zinc binding site 9 out
of 12 in 6foi
Go back to
Zinc Binding Sites List in 6foi
Zinc binding site 9 out
of 12 in the Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated.
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 9 of Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated. within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
Q:Zn201
b:26.9
occ:1.00
|
OD1
|
Q:ASP83
|
1.8
|
26.7
|
1.0
|
|
ND1
|
Q:HIS80
|
2.0
|
29.7
|
1.0
|
|
ND1
|
Q:HIS71
|
2.1
|
27.4
|
1.0
|
|
ND1
|
Q:HIS63
|
2.2
|
29.7
|
1.0
|
|
CG
|
Q:ASP83
|
2.7
|
26.4
|
1.0
|
|
OD2
|
Q:ASP83
|
2.9
|
26.2
|
1.0
|
|
CE1
|
Q:HIS80
|
2.9
|
30.3
|
1.0
|
|
CE1
|
Q:HIS71
|
2.9
|
26.8
|
1.0
|
|
CG
|
Q:HIS80
|
3.0
|
30.0
|
1.0
|
|
CG
|
Q:HIS63
|
3.1
|
31.2
|
1.0
|
|
CE1
|
Q:HIS63
|
3.1
|
29.4
|
1.0
|
|
CG
|
Q:HIS71
|
3.2
|
27.4
|
1.0
|
|
CB
|
Q:HIS63
|
3.4
|
32.4
|
1.0
|
|
CB
|
Q:HIS80
|
3.5
|
29.8
|
1.0
|
|
CB
|
Q:HIS71
|
3.7
|
28.4
|
1.0
|
|
O
|
Q:LYS136
|
3.8
|
30.1
|
1.0
|
|
CA
|
Q:HIS71
|
3.9
|
28.6
|
1.0
|
|
NE2
|
Q:HIS80
|
4.0
|
31.1
|
1.0
|
|
CD2
|
Q:HIS80
|
4.1
|
30.9
|
1.0
|
|
CB
|
Q:ASP83
|
4.1
|
26.2
|
1.0
|
|
NE2
|
Q:HIS71
|
4.1
|
26.4
|
1.0
|
|
NE2
|
Q:HIS63
|
4.2
|
30.6
|
1.0
|
|
CD2
|
Q:HIS71
|
4.3
|
26.7
|
1.0
|
|
CD2
|
Q:HIS63
|
4.3
|
31.8
|
1.0
|
|
CA
|
Q:ASP83
|
4.6
|
26.8
|
1.0
|
|
N
|
Q:HIS80
|
4.7
|
28.8
|
1.0
|
|
CA
|
Q:HIS80
|
4.7
|
29.8
|
1.0
|
|
N
|
Q:GLY72
|
4.7
|
26.9
|
1.0
|
|
C
|
Q:LYS136
|
4.8
|
30.2
|
1.0
|
|
N
|
Q:ASP83
|
4.9
|
27.9
|
1.0
|
|
O
|
Q:HOH341
|
4.9
|
29.4
|
1.0
|
|
C
|
Q:HIS71
|
4.9
|
27.6
|
1.0
|
|
N
|
Q:HIS71
|
4.9
|
30.1
|
1.0
|
|
CA
|
Q:HIS63
|
4.9
|
34.5
|
1.0
|
|
CD2
|
Q:HIS46
|
5.0
|
27.6
|
1.0
|
|
Zinc binding site 10 out
of 12 in 6foi
Go back to
Zinc Binding Sites List in 6foi
Zinc binding site 10 out
of 12 in the Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated.
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 10 of Human CYS57/156ALA Superoxide Dismutase-1 (SOD1), As Isolated. within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
S:Zn201
b:37.8
occ:0.80
|
OD1
|
S:ASP83
|
2.0
|
47.7
|
1.0
|
|
ND1
|
S:HIS71
|
2.1
|
52.6
|
1.0
|
|
ND1
|
S:HIS80
|
2.1
|
50.7
|
1.0
|
|
ND1
|
S:HIS63
|
2.2
|
50.7
|
1.0
|
|
CG
|
S:ASP83
|
2.8
|
47.9
|
1.0
|
|
OD2
|
S:ASP83
|
2.9
|
48.9
|
1.0
|
|
CE1
|
S:HIS71
|
3.0
|
52.4
|
1.0
|
|
CE1
|
S:HIS80
|
3.0
|
52.6
|
1.0
|
|
CG
|
S:HIS80
|
3.0
|
50.0
|
1.0
|
|
CG
|
S:HIS63
|
3.1
|
50.0
|
1.0
|
|
CG
|
S:HIS71
|
3.2
|
54.5
|
1.0
|
|
CE1
|
S:HIS63
|
3.2
|
51.7
|
1.0
|
|
CB
|
S:HIS63
|
3.4
|
49.1
|
1.0
|
|
CB
|
S:HIS80
|
3.4
|
48.2
|
1.0
|
|
O
|
S:LYS136
|
3.7
|
56.6
|
1.0
|
|
CB
|
S:HIS71
|
3.7
|
55.6
|
1.0
|
|
CA
|
S:HIS71
|
4.0
|
54.9
|
1.0
|
|
NE2
|
S:HIS80
|
4.1
|
53.2
|
1.0
|
|
CD2
|
S:HIS80
|
4.1
|
51.6
|
1.0
|
|
NE2
|
S:HIS71
|
4.1
|
54.0
|
1.0
|
|
CB
|
S:ASP83
|
4.2
|
47.1
|
1.0
|
|
CD2
|
S:HIS71
|
4.3
|
55.4
|
1.0
|
|
CD2
|
S:HIS63
|
4.3
|
50.5
|
1.0
|
|
NE2
|
S:HIS63
|
4.3
|
51.6
|
1.0
|
|
O
|
S:HOH301
|
4.4
|
34.3
|
1.0
|
|
CA
|
S:HIS80
|
4.6
|
48.2
|
1.0
|
|
N
|
S:HIS80
|
4.6
|
49.2
|
1.0
|
|
C
|
S:LYS136
|
4.8
|
58.8
|
1.0
|
|
N
|
S:GLY72
|
4.8
|
53.7
|
1.0
|
|
CA
|
S:ASP83
|
4.8
|
45.9
|
1.0
|
|
CA
|
S:HIS63
|
4.9
|
48.7
|
1.0
|
|
N
|
S:ASP83
|
4.9
|
45.0
|
1.0
|
|
N
|
S:HIS71
|
5.0
|
56.4
|
1.0
|
|
C
|
S:HIS71
|
5.0
|
55.3
|
1.0
|
|
Reference:
F.A.Sala,
G.S.A.Wright,
S.V.Antonyuk,
R.C.Garratt,
S.S.Hasnain.
Molecular Recognition and Maturation of SOD1 By Its Evolutionarily Destabilised Cognate Chaperone Hccs. Plos Biol. V. 17 00141 2019.
ISSN: ESSN 1545-7885
PubMed: 30735496
DOI: 10.1371/JOURNAL.PBIO.3000141
Page generated: Thu Aug 21 14:22:06 2025
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