Zinc in PDB 6owj: Zn-Mediated Polymerization of Human Sfpq

The structure of Zn-Mediated Polymerization of Human Sfpq, PDB code: 6owj was solved by M.Lee, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.38 / 1.94
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	61.230, 62.450, 67.880, 90.00, 95.74, 90.00
R / Rfree (%)	17.6 / 21.8

The binding sites of Zinc atom in the Zn-Mediated Polymerization of Human Sfpq (pdb code 6owj). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Zn-Mediated Polymerization of Human Sfpq, PDB code: 6owj:

Zinc binding site 1 out of 1 in the Zn-Mediated Polymerization of Human Sfpq


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Zn-Mediated Polymerization of Human Sfpq within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn601 b:22.6 occ:1.00 NE2 A:HIS483 2.0 23.8 1.0 NE2 B:HIS530 2.0 18.7 1.0 CE1 A:HIS483 3.0 24.2 1.0 CD2 B:HIS530 3.0 18.4 1.0 CE1 B:HIS530 3.0 18.0 1.0 CD2 A:HIS483 3.1 23.9 1.0 ND1 A:HIS483 4.2 24.2 1.0 CG B:HIS530 4.2 18.1 1.0 ND1 B:HIS530 4.2 19.9 1.0 CG A:HIS483 4.2 22.8 1.0 O A:HOH796 4.5 25.0 1.0

J.Huang, M.Ringuet, A.Whitten, S.Caria, Y.W.Lim, R.Badhan, V.Anggono, M.Lee. Structural Basis of the Zinc-Induced Cytoplasmic Aggregation of the Rna-Binding Protein Sfpq Nucleic Acids Res. 2020.
ISSN: ESSN 1362-4962
DOI: 10.1093/NAR/GKAA076