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Atomistry » Zinc » PDB 5onk-5phh » 5opc » |
Zinc in PDB 5opc: Factor Inhibiting Hif (Fih) in Complex with Zinc and VadadustatEnzymatic activity of Factor Inhibiting Hif (Fih) in Complex with Zinc and Vadadustat
All present enzymatic activity of Factor Inhibiting Hif (Fih) in Complex with Zinc and Vadadustat:
1.14.11.30; Protein crystallography data
The structure of Factor Inhibiting Hif (Fih) in Complex with Zinc and Vadadustat, PDB code: 5opc
was solved by
T.M.Leissing,
C.J.Schofield,
I.J.Clifton,
X.Lu,
D.Zhang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5opc:
The structure of Factor Inhibiting Hif (Fih) in Complex with Zinc and Vadadustat also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Factor Inhibiting Hif (Fih) in Complex with Zinc and Vadadustat
(pdb code 5opc). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Factor Inhibiting Hif (Fih) in Complex with Zinc and Vadadustat, PDB code: 5opc: Zinc binding site 1 out of 1 in 5opcGo back to![]() ![]()
Zinc binding site 1 out
of 1 in the Factor Inhibiting Hif (Fih) in Complex with Zinc and Vadadustat
![]() Mono view ![]() Stereo pair view
Reference:
T.L.Yeh,
T.M.Leissing,
M.I.Abboud,
C.C.Thinnes,
O.Atasoylu,
J.P.Holt-Martyn,
D.Zhang,
A.Tumber,
K.Lippl,
C.T.Lohans,
I.K.H.Leung,
H.Morcrette,
I.J.Clifton,
T.D.W.Claridge,
A.Kawamura,
E.Flashman,
X.Lu,
P.J.Ratcliffe,
R.Chowdhury,
C.W.Pugh,
C.J.Schofield.
Molecular and Cellular Mechanisms of Hif Prolyl Hydroxylase Inhibitors in Clinical Trials. Chem Sci V. 8 7651 2017.
Page generated: Sun Oct 27 23:45:39 2024
ISSN: ISSN 2041-6520 PubMed: 29435217 DOI: 10.1039/C7SC02103H |
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