Zinc in PDB 4w8y: Structure of Full Length CMR2 From Pyrococcus Furiosus (Manganese Bound Form)

The structure of Structure of Full Length CMR2 From Pyrococcus Furiosus (Manganese Bound Form), PDB code: 4w8y was solved by C.Benda, J.Ebert, M.Baumgaertner, E.Conti, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	85.72 / 3.00
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	62.400, 167.925, 100.908, 90.00, 98.91, 90.00
R / Rfree (%)	22.3 / 25.9

The structure of Structure of Full Length CMR2 From Pyrococcus Furiosus (Manganese Bound Form) also contains other interesting chemical elements:

Manganese

(Mn)

8 atoms

The binding sites of Zinc atom in the Structure of Full Length CMR2 From Pyrococcus Furiosus (Manganese Bound Form) (pdb code 4w8y). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of Full Length CMR2 From Pyrococcus Furiosus (Manganese Bound Form), PDB code: 4w8y:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of Full Length CMR2 From Pyrococcus Furiosus (Manganese Bound Form)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Full Length CMR2 From Pyrococcus Furiosus (Manganese Bound Form) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn901 b:64.9 occ:1.00 SG A:CYS451 2.3 82.2 1.0 SG A:CYS481 2.3 74.1 1.0 SG A:CYS448 2.3 66.4 1.0 SG A:CYS478 2.3 73.6 1.0 CB A:CYS448 2.8 72.9 1.0 CB A:CYS481 3.1 63.7 1.0 CB A:CYS451 3.3 76.6 1.0 CB A:CYS478 3.4 64.6 1.0 N A:CYS451 3.7 68.6 1.0 N A:CYS478 4.0 63.8 1.0 CA A:CYS451 4.1 70.5 1.0 CA A:CYS478 4.3 63.8 1.0 CA A:CYS481 4.3 61.5 1.0 CA A:CYS448 4.3 67.5 1.0 N A:CYS481 4.3 60.2 1.0 CB A:VAL450 4.6 77.7 1.0 CB A:ASN454 4.6 80.7 1.0 O A:HOH1016 4.7 63.1 1.0 N A:GLY452 4.7 79.0 1.0 C A:VAL450 4.7 73.8 1.0 C A:CYS448 4.8 68.1 1.0 N A:VAL450 4.9 75.2 1.0 C A:CYS478 4.9 66.7 1.0 C A:CYS451 4.9 77.5 1.0 O A:CYS478 4.9 68.5 1.0 ND2 A:ASN454 4.9 84.5 1.0 CA A:VAL450 5.0 75.0 1.0

Zinc binding site 2 out of 2 in the Structure of Full Length CMR2 From Pyrococcus Furiosus (Manganese Bound Form)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Full Length CMR2 From Pyrococcus Furiosus (Manganese Bound Form) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn901 b:86.0 occ:1.00 SG B:CYS481 2.2 68.4 1.0 SG B:CYS451 2.2 79.1 1.0 SG B:CYS478 2.3 73.2 1.0 SG B:CYS448 2.3 73.1 1.0 CB B:CYS448 2.9 72.3 1.0 CB B:CYS481 3.1 67.7 1.0 CB B:CYS451 3.2 81.3 1.0 CB B:CYS478 3.4 71.5 1.0 N B:CYS451 3.8 72.5 1.0 N B:CYS478 3.9 66.3 1.0 CA B:CYS451 4.1 77.2 1.0 N B:CYS481 4.2 61.1 1.0 CA B:CYS478 4.2 67.6 1.0 CA B:CYS481 4.2 62.3 1.0 CA B:CYS448 4.4 69.5 1.0 CB B:ASN454 4.6 86.2 1.0 CB B:VAL450 4.7 78.9 1.0 N B:GLY452 4.8 80.8 1.0 C B:CYS478 4.8 68.1 1.0 O B:CYS478 4.8 67.1 1.0 C B:VAL450 4.8 76.3 1.0 C B:CYS448 4.9 73.1 1.0 ND2 B:ASN454 4.9 95.8 1.0 C B:CYS451 5.0 83.0 1.0

C.Benda, J.Ebert, R.A.Scheltema, H.B.Schiller, M.Baumgartner, F.Bonneau, M.Mann, E.Conti. Structural Model of A Crispr Rna-Silencing Complex Reveals the Rna-Target Cleavage Activity in CMR4. Mol.Cell V. 56 43 2014.
ISSN: ISSN 1097-2765
PubMed: 25280103
DOI: 10.1016/J.MOLCEL.2014.09.002